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22
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4143143325
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note
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A control experiment performed in the absence of Pd provided <5% of 2.
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23
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4143114788
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note
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2 = 38% ee.
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24
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4143127955
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note
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The absolute configuration of 2 is as shown and was determined by X-ray analysis of the corresponding iodolactonized ketone; all other compounds are assigned by analogy: see Supporting Information.
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25
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0025780257
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The negligible effect of temperature on enantioselectivtiy has been observed in other systems; Buschmann, H.; Scharf, H.-D.; Hoffmann, N.; Esser, P. Angew. Chem., Int. Ed. Engl. 1991, 30, 477-515.
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26
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0032927129
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We have observed dramatic effects of styrenic promoters in the nickel-catalyzed anhydride alkylation; see: ref 6. For use of olefins as reductive elimination promoters, see: Giovannini, R.; Studemann, T.; Devasagayaraj, A.; Dussin, G.; Knochel, P. J. Org. Chem. 1999, 64, 3544-3553.
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