Cardiovascular pharmacological characterization of novel 2,3-dimethyl-2-butylamine derivatives in rats

Life Sciences

Volumn 75, Issue 17, 2004, Pages 2131-2142

  Chen, Yu Ping ^b   Qiu, Cai Rong ^b   Wang, Hai ^a  

^a BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^b NONE

Author keywords

2,3 Dimethyl 2 butylamine derivatives; K + channel opener; Smooth muscle cells; Tail artery

Indexed keywords

ALKYL GROUP; BUTYLAMINE; CARBON; FUNCTIONAL GROUP; GLIBENCLAMIDE; PINACIDIL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; PYRIDINE;

ANESTHESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CARDIOVASCULAR EFFECT; CARDIOVASCULAR PARAMETERS; CARDIOVASCULAR RESPONSE; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; DIASTOLE; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ELECTROPHYSIOLOGY; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HEART RATE; HEMODYNAMIC PARAMETERS; IN VITRO STUDY; IN VIVO STUDY; MALE; MEAN ARTERIAL PRESSURE; MUSCLE FIBER MEMBRANE; NONHUMAN; POTASSIUM CURRENT; RAT; SMOOTH MUSCLE FIBER; STATISTICAL SIGNIFICANCE; TAIL ARTERY;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ARTERIES; BLOOD PRESSURE; BUTYLAMINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYBURIDE; HEART RATE; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCARDIAL CONTRACTION; PATCH-CLAMP TECHNIQUES; POTASSIUM; POTASSIUM CHANNELS; RATS; RATS, WISTAR; TAIL; TIME FACTORS;

EID: 4143103522     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.06.003     Document Type: Article

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