NPPB block of the intermediate-conductance Ca 2+-activated K + channel

European Journal of Pharmacology

Volumn 497, Issue 1, 2004, Pages 1-6

  Fioretti, Bernard ^a   Castigli, Emilia ^a   Calzuola, Isabella ^a   Harper, Alexander A ^b   Franciolini, Fabio ^a   Catacuzzeno, Luigi ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Cl current; GL 15 cell; HL 60 cell; Intermediate conductance Ca 2+ activated K + channel; NPPB; Patch clamp recording

Indexed keywords

1 (2 HYDROXY 5 TRIFLUOROMETHYLPHENYL) 5 TRIFLUOROMETHYL 2(3H) BENZIMIDAZOLONE; 1 ETHYL 2 BENZIMIDAZOLINONE; 5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CHARYBDOTOXIN; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CLOTRIMAZOLE; IONOMYCIN; NITRENDIPINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; TETRYLAMMONIUM; TUBOCURARINE CHLORIDE;

ARTICLE; CELL LINE; CELL STRAIN HL 60; CHLORIDE CURRENT; CONTROLLED STUDY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IC 50; ION CONDUCTANCE; ION CURRENT; PRIORITY JOURNAL; RECORDING;

CELL LINE, TUMOR; CHLORIDE CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; NITROBENZOATES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED;

EID: 4143100513     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.06.034     Document Type: Article

References (24)

1. V. Bocchini, R. Casalone, P. Collini, G. Rebel, and F. Lo Curto Changes in glial fibrillary acidic protein and karyotype during culturing of two cell lines established from human glioblastoma multiforme Cell Tissue Res. 265 1991 73 81
2. N.A. Castle Recent advances in the biology of small conductance calcium-activated potassium channels Perspect. Drug Discov. Des. 15 1999 131 154
3. J.M. Doughty, A.L. Miller, and P.D. Langton Non-specificity of chloride channel blockers in rat cerebral arteries: block of the L-type calcium channel J. Physiol. 507 1998 433 439
4. S. Eskandari, G.A. Zampighi, D.W. Leung, E.M. Wright, and D.D. Loo Inhibition of gap junction hemichannels by chloride channel blockers J. Membr. Biol. 185 2002 93 102
5. 2+-activated K channels in glioblastoma GL-15 human cell line and their distinct modulation by ERK1/2 Pflugers Arch. 2004 (Abstr, in press)
6. O. Gavrilova-Ruch, K. Schonherr, G. Gessner, R. Schonherr, T. Klapperstuck, W. Wohlrab, and S.H. Heinemann Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells J. Membr. Biol. 188 2002 137 149
7. S. Ghanshani, H. Wulff, M.J. Miller, H. Rohm, A. Neben, G.A. Gutman, M.D. Cahalan, and K.G. Chandy Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences J. Biol. Chem. 275 2000 37137 37149
8. V.K. Gribkoff, J.T. Lum-Ragan, C.G. Boissard, D.J. Post-Munson, N.A. Meanwell, J.E. Starrett Jr., E.S. Kozlowski, J.L. Romine, J.T. Trojnacki, M.C. Mckay, J. Zhong, and S.I. Dworetzky Effects of channel modulators on cloned large-conductance calcium-activated potassium channels Mol. Pharmacol. 50 1996 206 217
9. 2+ Am. J. Physiol. 263 1992 C674 C683
10. + channel Am. J. Physiol. 275 1998 C848 C856
11. + channel of intermediate conductance: a molecular target for novel treatments? Curr. Drugs, Targets 2 2001 401 422
12. T.J. Jentsch, V. Stein, F. Weinreich, and A.A. Zdebik Molecular structure and physiological function of chloride channels Physiol. Rev. 82 2002 503 568
13. + channels and the microglial respiratory burst Am. J. Physiol., Cell Physiol. 280 2001 C796 C806
14. R. Kohler, H. Wulff, I. Eichler, M. Kneifel, D. Neumann, A. Knorr, I. Grgic, D. Kampfe, H. Si, J. Wibawa, R. Real, K. Borner, S. Brakemeier, H.D. Orzechowski, H.P. Reusch, M. Paul, K.G. Chandy, and J. Hoyer Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis Circulation 108 2003 1119 1125
15. 2+ channel block by 5-nitro-2-(3-phenylpropylamino)-benzoic acid in Jurkat cells Eur. J. Pharmacol. 394 2000 171 179
16. Y. Okada, E. Maeno, T. Shimizu, K. Dezaki, J. Wang, and S. Morishima Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD) J. Physiol. 532 2001 3 16
17. C.B. Ransom, J.T. O'Neal, and H. Sontheimer Volume-activated chloride currents contribute to the resting conductance and invasive migration of human glioma cells J. Neurosci. 21 2001 7674 7683
18. +-conducting channels by diphenylamine-2-carboxylate in turtle colon epithelial cells J. Physiol. 462 1993 715 734
19. B.D. Schultz, A.K. Singh, D.C. Devor, and R.J. Bridges Pharmacology of CFTR chloride channel activity Physiol. Rev. 79 1999 S109 S144
20. A. Schwab Ion channels and transporters on the move News Physiol. Sci. 16 2001 29 33
21. C. Vergara, R. Latorre, N.V. Marrion, and J.P. Adelman Calcium-activated potassium channels Curr. Opin. Neurobiol. 8 1998 321 329
22. J. Wang, S. Morishima, and Y. Okada IK channels are involved in the regulatory volume decrease in human epithelial cells Am. J. Physiol., Cell Physiol. 284 2003 C77 C84
23. + channel (rSK4) of colonic crypts Pflugers Arch. 438 1999 437 444
24. + conductance in HL-60 cells Biol. Chem. 267 1992 15426 15431