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Volumn , Issue 10, 2004, Pages 1826-1828

Ethyl propiolate: A simple and convenient peptide coupling reagent

Author keywords

Coupling reagent; Peptide; Sodium bisulfite

Indexed keywords

ALKYNE DERIVATIVE; PROPIONIC ACID ETHYL ESTER; UNCLASSIFIED DRUG;

EID: 4143095905     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-829553     Document Type: Article
Times cited : (6)

References (23)
  • 12
    • 80051638714 scopus 로고    scopus 로고
    • Goodman, M., Ed.; Georg Thieme Verlag: Stuttgart
    • Reviews: (a) Albericio, F.; Chinchilla, R.; Dodsworth, D. J.; Nájera, C. Org. Prep. Proc. Int. 2001, 33, 203. (b) Methods in Organic Chemistry (Houben-Weyl), Vol. E22a; Goodman, M., Ed.; Georg Thieme Verlag: Stuttgart, 2002.
    • (2002) Methods in Organic Chemistry (Houben-Weyl) , vol.E22A
  • 13
    • 0026418434 scopus 로고
    • (a) Trost, B. M. Science 1991, 254, 1471.
    • (1991) Science , vol.254 , pp. 1471
    • Trost, B.M.1
  • 20
    • 0034867881 scopus 로고    scopus 로고
    • and references cited therein
    • For a review on the activation of conjugated alkynes with phosphines, see: Lu, X.; Zhang, C.; Xu, Z. Acc. Chem. Res. 2001, 34, 535; and references cited therein.
    • (2001) Acc. Chem. Res. , vol.34 , pp. 535
    • Lu, X.1    Zhang, C.2    Xu, Z.3
  • 21
    • 4143058620 scopus 로고    scopus 로고
    • note
    • The mechanism is believed to imply the catalysis of the tertiary amine (Scheme 1) and not a direct Michael addition of the carboxylate since no reaction is observed in the presence of various inorganic bases.
  • 22
    • 4143101957 scopus 로고    scopus 로고
    • note
    • 1H NMR on the crude mixture.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.