A Novel Single Nucleotide Polymorphism (SNP) of the CYP2CI9 Gene in a Japanese Subject with Lowered Capacity of Mephobarbital 4'-Hydroxylation

Drug Metabolism And Pharmacokinetics

Volumn 19, Issue 3, 2004, Pages 236-238

  Morita, Jun ^a   Kobayashi, Kaoru ^a   Wanibuchi, Atsuko ^b   Kimura, Miyuki ^b   Irie, Shin ^b   Ishizaki, Takashi ^c   Chiba, Kan ^a  

^a CHIBA UNIVERSITY   (Japan)

^b Kyushu Clinical Pharmacology Research Clinic   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

amino acid substitution; CYP2C19; Japanese; novel SNP

Indexed keywords

ARGININE; CYP2C19 PROTEIN, HUMAN; CYSTEINE; METHYLPHENOBARBITAL; MIXED FUNCTION OXIDASE; UNSPECIFIC MONOOXYGENASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; ASIAN; CASE REPORT; ENZYME ACTIVATION; GENETICS; HETEROZYGOTE DETECTION; HUMAN; HYDROXYLATION; MALE; METABOLISM; MOLECULAR GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARGININE; ARYL HYDROCARBON HYDROXYLASES; ASIAN CONTINENTAL ANCESTRY GROUP; CYSTEINE; ENZYME ACTIVATION; HETEROZYGOTE DETECTION; HUMANS; HYDROXYLATION; MALE; MEPHOBARBITAL; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 4143089796     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.19.236     Document Type: Article

References (4)

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