-
1
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry N.A., Lazebnik Y. Caspases: enemies within. Science. 281:1998;1312-1316
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
3
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
-
Boldin M.P., Goncharov T.M., Goltsev Y.V., Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell. 85:1996;803-815
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
4
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signal complex
-
Muzio M., Chinnaiyan A.M., Kischkell F.C., O'Rourke K., Shevchenko A., Ni J., Scaffidi C., Bretz J.D., Zhang M., Gentz R., Mann M., Krammer P.H., Peter M.E., Dixit V.M. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signal complex. Cell. 85:1996;817-827
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkell, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
Mann, M.11
Krammer, P.H.12
Peter, M.E.13
Dixit, V.M.14
-
5
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema J.P., Scaffidi C., Kischkel F.C., Shevchenko A., Mann M., Krammer P.H., Peter M.E. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16:1997;2794-2804
-
(1997)
EMBO J.
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
Krammer, P.H.6
Peter, M.E.7
-
6
-
-
0032548842
-
Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHα1) death signal
-
Martin D.A., Siegel R.M., Zheng L., Lenardo M.J. Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHα1) death signal. J. Biol. Chem. 273:1998;4345-4349
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 4345-4349
-
-
Martin, D.A.1
Siegel, R.M.2
Zheng, L.3
Lenardo, M.J.4
-
7
-
-
0029905073
-
Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
-
Srinivasula S.M., Ahmad M., Fernandes-Alnemri T., Litwack G., Alnemri E.S. Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc. Natl. Acad. Sci. U. S. A. 93:1996;14486-14491
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 14486-14491
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Litwack, G.4
Alnemri, E.S.5
-
8
-
-
0033580926
-
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
-
Saleh A., Srinivasula S.M., Acharya S., Fishel R., Alnemri E.S. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J. Biol. Chem. 274:1999;17941-17945
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17941-17945
-
-
Saleh, A.1
Srinivasula, S.M.2
Acharya, S.3
Fishel, R.4
Alnemri, E.S.5
-
9
-
-
0037007101
-
Oligomerization and activation of caspase-9, induced by Apaf-1 CARD
-
Shiozaki E.N., Chai J., Shi Y. Oligomerization and activation of caspase-9, induced by Apaf-1 CARD. Proc. Natl. Acad. Sci. U. S. A. 99:2002;4197-4202
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 4197-4202
-
-
Shiozaki, E.N.1
Chai, J.2
Shi, Y.3
-
10
-
-
0029787268
-
Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases
-
Orth K., O'Rourke K., Salvesen G.S., Dixit V.M. Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases. J. Biol. Chem. 271:1996;20977-20980
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20977-20980
-
-
Orth, K.1
O'Rourke, K.2
Salvesen, G.S.3
Dixit, V.M.4
-
11
-
-
0028990125
-
Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M., Quan L.T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81:1995;801-809
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
12
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A., Dixit V.M. Death receptors: signaling and modulation. Science. 281:1998;1305-1308
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
13
-
-
0032575752
-
Mitochondria and apoptosis
-
Green D.R., Reed J.C. Mitochondria and apoptosis. Science. 281:1998;1309-1312
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
14
-
-
0031663369
-
The green fluorescent protein
-
Tsien R.Y. The green fluorescent protein. Annu. Rev. Biochem. 67:1998;509-544
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 509-544
-
-
Tsien, R.Y.1
-
17
-
-
0033622319
-
A genetically encoded, fluorescent indicator for cyclic AMP in living cells
-
Zaccolo M., Giorgi F.D., Cho C.Y., Feng L., Knapp T., Negulescu P.A., Taylor S.S., Tsien R.Y., Pozzan T. A genetically encoded, fluorescent indicator for cyclic AMP in living cells. Nat. Cell Biol. 2:2000;25-29
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 25-29
-
-
Zaccolo, M.1
Giorgi, F.D.2
Cho, C.Y.3
Feng, L.4
Knapp, T.5
Negulescu, P.A.6
Taylor, S.S.7
Tsien, R.Y.8
Pozzan, T.9
-
18
-
-
0034019496
-
A fluorescent indicator for visualizing cAMP-induced phosphorylation in vivo
-
Nagai Y., Miyazaki M., Aoki R., Zama T., Inouye S., Hirose K., Iino M., Hagiwara M. A fluorescent indicator for visualizing cAMP-induced phosphorylation in vivo. Nat. Biotech. 18:2000;313-316
-
(2000)
Nat. Biotech.
, vol.18
, pp. 313-316
-
-
Nagai, Y.1
Miyazaki, M.2
Aoki, R.3
Zama, T.4
Inouye, S.5
Hirose, K.6
Iino, M.7
Hagiwara, M.8
-
19
-
-
0034023407
-
Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells
-
Dantuma N.P., Lindsten K., Glas R., Jellne M., Masucci M.G. Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells. Nat. Biotechnol. 18:2000;538-543
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 538-543
-
-
Dantuma, N.P.1
Lindsten, K.2
Glas, R.3
Jellne, M.4
Masucci, M.G.5
-
20
-
-
0034671963
-
Fluorescent indicators for cyclic GMP based on cyclic GMP-dependent protein kinase Iα and green fluorescent proteins
-
Sato M., Hida N., Ozawa T., Umezawa Y. Fluorescent indicators for cyclic GMP based on cyclic GMP-dependent protein kinase Iα and green fluorescent proteins. Anal. Chem. 72:2000;5918-5924
-
(2000)
Anal. Chem.
, vol.72
, pp. 5918-5924
-
-
Sato, M.1
Hida, N.2
Ozawa, T.3
Umezawa, Y.4
-
22
-
-
0035903217
-
A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo
-
Kurokawa K., Mochizuki N., Ohba Y., Mizuno H., Miyawaki A., Matsuda M. A pair of fluorescent resonance energy transfer-based probes for tyrosine phosphorylation of the CrkII adaptor protein in vivo. J. Biol. Chem. 276:2001;31305-31310
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31305-31310
-
-
Kurokawa, K.1
Mochizuki, N.2
Ohba, Y.3
Mizuno, H.4
Miyawaki, A.5
Matsuda, M.6
-
23
-
-
0035910074
-
Genetically encoded reporters of proein kinase a activity reveal impact of substrate tethering
-
Zhang J., Ma Y., Taylor S.S., Tsien R.Y. Genetically encoded reporters of proein kinase A activity reveal impact of substrate tethering. Proc. Natl. Acad. Sci. U. S. A. 98:2001;14997-15002
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 14997-15002
-
-
Zhang, J.1
Ma, Y.2
Taylor, S.S.3
Tsien, R.Y.4
-
24
-
-
0035909994
-
Geneically encoded fluorescent reporters of protein kinase activities in living cells
-
Ting A.Y., Kain K.H., Klemke R.L., Tsien R.Y. Geneically encoded fluorescent reporters of protein kinase activities in living cells. Proc. Natl. Acad. Sci. U. S. A. 98:2001;15003-15008
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 15003-15008
-
-
Ting, A.Y.1
Kain, K.H.2
Klemke, R.L.3
Tsien, R.Y.4
-
25
-
-
0036196296
-
Fluorescent indicators for imaging protein phosphorylation in single living cells
-
Sato M., Ozawa T., Inukai K., Asano T., Umezawa Y. Fluorescent indicators for imaging protein phosphorylation in single living cells. Nat. Biotechnol. 20:2002;287-294
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 287-294
-
-
Sato, M.1
Ozawa, T.2
Inukai, K.3
Asano, T.4
Umezawa, Y.5
-
26
-
-
0037780971
-
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
-
Violin J.D., Zhang J., Tsien R.Y., Newton A.C. A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C. J. Cell Biol. 161:2003;899-909
-
(2003)
J. Cell Biol.
, vol.161
, pp. 899-909
-
-
Violin, J.D.1
Zhang, J.2
Tsien, R.Y.3
Newton, A.C.4
-
27
-
-
0035442412
-
The use of FRET imaging microscopy to detect protein-protein interactions and protein conformational changes in vivo
-
Truong K., Ikura M. The use of FRET imaging microscopy to detect protein-protein interactions and protein conformational changes in vivo. Curr. Opin. Struck. Biol. 11:2001;573-578
-
(2001)
Curr. Opin. Struck. Biol.
, vol.11
, pp. 573-578
-
-
Truong, K.1
Ikura, M.2
-
28
-
-
0034280126
-
Rapid caspase-3 activation during apoptosis revealed using fluorescence-resonance energy transfer
-
Tyas L., Brophy V.A., Pope A., Rivett A.J., Tavaré J.M. Rapid caspase-3 activation during apoptosis revealed using fluorescence-resonance energy transfer. EMBO Rep. 1:2000;266-270
-
(2000)
EMBO Rep.
, vol.1
, pp. 266-270
-
-
Tyas, L.1
Brophy, V.A.2
Pope, A.3
Rivett, A.J.4
Tavaré, J.M.5
-
29
-
-
0037025346
-
Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process: Role of caspase-3
-
Rehm M., Düßmann H., Jänicke R.U., Tavaré J.M., Kögel D., Prehn J.H.M. Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process: role of caspase-3. J. Biol. Chem. 277:2002;24506-24514
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24506-24514
-
-
Rehm, M.1
Düßmann, H.2
Jänicke, R.U.3
Tavaré, J.M.4
Kögel, D.5
Prehn, J.H.M.6
-
30
-
-
0034801529
-
Application of the fluorescence resonance energy transfer method for studying the dynamics of caspase-3 activation during UV-induced apoptosis in living HeLa cells
-
Luo K.Q., Yu V.C., Pu Y., Chang D.C. Application of the fluorescence resonance energy transfer method for studying the dynamics of caspase-3 activation during UV-induced apoptosis in living HeLa cells. Biochem. Biophys. Res. Commun. 283:2001;1054-1060
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.283
, pp. 1054-1060
-
-
Luo, K.Q.1
Yu, V.C.2
Pu, Y.3
Chang, D.C.4
-
31
-
-
0035135471
-
Measurement of caspase activity in individual cells reveals differences in the kinetics of caspase activation between cells
-
Morgan M.J., Thorburn A. Measurement of caspase activity in individual cells reveals differences in the kinetics of caspase activation between cells. Cell Death Differ. 8:2001;38-43
-
(2001)
Cell Death Differ.
, vol.8
, pp. 38-43
-
-
Morgan, M.J.1
Thorburn, A.2
-
32
-
-
0037069360
-
Confirmation by FRET in individual living cells of the absence of significant amyloid β-mediated caspase 8 activation
-
Ohnuki R., Nagasaki A., Kawasaki H., Baba T., Uyeda T.Q.P., Taira K. Confirmation by FRET in individual living cells of the absence of significant amyloid β-mediated caspase 8 activation. Proc. Natl. Acad. Sci. U. S. A. 99:2002;14716-14721
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 14716-14721
-
-
Ohnuki, R.1
Nagasaki, A.2
Kawasaki, H.3
Baba, T.4
Uyeda, T.Q.P.5
Taira, K.6
-
33
-
-
0037455553
-
Spatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effects
-
Takemoto K., Nagai T., Miyawaki A., Miura M. Spatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effects. J. Cell Biol. 160:2003;235-243
-
(2003)
J. Cell Biol.
, vol.160
, pp. 235-243
-
-
Takemoto, K.1
Nagai, T.2
Miyawaki, A.3
Miura, M.4
-
34
-
-
0037414451
-
Measuring dynamics of caspase-8 activation in a single living HeLa cell during TNFalpha-induced apoptosis
-
Luo K.Q., Yu V.C., Pu Y., Chang D.C. Measuring dynamics of caspase-8 activation in a single living HeLa cell during TNFalpha-induced apoptosis. Biochem. Biophys. Res. Commun. 304:2003;217-222
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 217-222
-
-
Luo, K.Q.1
Yu, V.C.2
Pu, Y.3
Chang, D.C.4
-
35
-
-
0027973061
-
CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme
-
Fernandes-Alnemri T., Litwack G., Alnemri E.S. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J. Biol. Chem. 269:1994;30761-30764
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30761-30764
-
-
Fernandes-Alnemri, T.1
Litwack, G.2
Alnemri, E.S.3
-
36
-
-
0023186234
-
Molecular cloning of cDNA for human poly(ADP-rybose) polymerase and expression of its gene during HL-60 cell differentiation
-
Suzuki H., Uchida K., Shima H., Sato T., Okamoto T., Kimura T., Miwa M. Molecular cloning of cDNA for human poly(ADP-rybose) polymerase and expression of its gene during HL-60 cell differentiation. Biochem. Biophys. Res. Commun. 146:1987;403-409
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.146
, pp. 403-409
-
-
Suzuki, H.1
Uchida, K.2
Shima, H.3
Sato, T.4
Okamoto, T.5
Kimura, T.6
Miwa, M.7
-
37
-
-
0345120940
-
Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives
-
Scaduto R.C. Jr., Grotyohann L.W. Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys. J. 76:1999;469-477
-
(1999)
Biophys. J.
, vol.76
, pp. 469-477
-
-
Scaduto Jr., R.C.1
Grotyohann, L.W.2
-
38
-
-
0035504737
-
Correlating cell cycle with apoptosis in a cell line expressing a tandem green fluorescent protein substrate specific for group II caspases
-
Donahue C.J., Santoro M., Hupe D., Jones J.M., Pollok B., Heim R., Giegel D. Correlating cell cycle with apoptosis in a cell line expressing a tandem green fluorescent protein substrate specific for group II caspases. Cytometry. 45:2001;225-234
-
(2001)
Cytometry
, vol.45
, pp. 225-234
-
-
Donahue, C.J.1
Santoro, M.2
Hupe, D.3
Jones, J.M.4
Pollok, B.5
Heim, R.6
Giegel, D.7
-
39
-
-
0038239643
-
Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line
-
Yamasaki F., Hama S., Yoshioka H., Kajiwara Y., Yahara K., Sugiyama K., Heike Y., Arita K., Kurisu K. Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line. Cancer Chemother. Pharmacol. 51:2003;271-283
-
(2003)
Cancer Chemother. Pharmacol.
, vol.51
, pp. 271-283
-
-
Yamasaki, F.1
Hama, S.2
Yoshioka, H.3
Kajiwara, Y.4
Yahara, K.5
Sugiyama, K.6
Heike, Y.7
Arita, K.8
Kurisu, K.9
-
40
-
-
0034759102
-
Multiple kinetics of mitochondrial cytochrome c release in drug-induced apoptosis
-
Luetjens C.M., Kögel D., Reimertz C., Dübmann H., Renz A., Schulze-Osthoff K., Nieminen A.-L., Poppe M., Prehn J.H.M. Multiple kinetics of mitochondrial cytochrome c release in drug-induced apoptosis. Mol. Pharmacol. 60:2001;1008-1019
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 1008-1019
-
-
Luetjens, C.M.1
Kögel, D.2
Reimertz, C.3
Dübmann, H.4
Renz, A.5
Schulze-Osthoff, K.6
Nieminen, A.-L.7
Poppe, M.8
Prehn, J.H.M.9
-
41
-
-
0142049202
-
Mitochondrial membrane permeabilization and superoxide production during apoptosis: A single-cell analysis
-
Düssmann H., Kögel D., Rehm M., Prehn J.H.M. Mitochondrial membrane permeabilization and superoxide production during apoptosis: a single-cell analysis. J. Biol. Chem. 278:2003;12645-12649
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12645-12649
-
-
Düssmann, H.1
Kögel, D.2
Rehm, M.3
Prehn, J.H.M.4
-
42
-
-
0036423710
-
On the release of cytochrome c from mitochondria during cell death signaling
-
Lim M.L.R., Lum M.-G., Hansen T.M., Roucou X., Nagley P. On the release of cytochrome c from mitochondria during cell death signaling. J. Biomed. Sci. 9:2002;488-506
-
(2002)
J. Biomed. Sci.
, vol.9
, pp. 488-506
-
-
Lim, M.L.R.1
Lum, M.-G.2
Hansen, T.M.3
Roucou, X.4
Nagley, P.5
-
43
-
-
0033781027
-
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
-
Goldstein J.C., Waterhouse N.J., Juin P., Evan G.I., Green D.R. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat. Cell Biol. 2:2000;156-162
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 156-162
-
-
Goldstein, J.C.1
Waterhouse, N.J.2
Juin, P.3
Evan, G.I.4
Green, D.R.5
-
44
-
-
0037085380
-
Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization
-
Madesh M., Antonsson B., Srinivasula S.M., Alenemri E.S., Hajnóczky G. Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization. J. Biol. Chem. 277:2002;5651-5659
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5651-5659
-
-
Madesh, M.1
Antonsson, B.2
Srinivasula, S.M.3
Alenemri, E.S.4
Hajnóczky, G.5
-
45
-
-
0036548511
-
The permeability transition pore signals apoptosis by directing Bax translocation and multimerization
-
De Giorgi F., Lartigue L., Baure M.K.A., Schubert A., Grimm S., Hanson G.T., Remington S.J., Youle R.J., Ichas F. The permeability transition pore signals apoptosis by directing Bax translocation and multimerization. FASEB J. 16:2002;607-609
-
(2002)
FASEB J.
, vol.16
, pp. 607-609
-
-
De Giorgi, F.1
Lartigue, L.2
Baure, M.K.A.3
Schubert, A.4
Grimm, S.5
Hanson, G.T.6
Remington, S.J.7
Youle, R.J.8
Ichas, F.9
|