Producing transglutaminases by molecular farming in plants: Minireview article

Amino Acids

Volumn 26, Issue 4, 2004, Pages 419-423

  Capell, T ^a   Claparols, I ^b   Del Duca, S ^c   Bassie, L ^a   Miro, B ^a   Rodriguez Montesinos, J ^a   Christou, P ^a   Serafini Fracassini, D ^c  

^a FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^b INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Biotechnology; Molecular farming; Plants; Recombinant protein; Transglutaminase

Indexed keywords

PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; RECOMBINANT ENZYME;

CATALYSIS; CONFERENCE PAPER; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SYNTHESIS; FARMING SYSTEM; MOLECULAR BIOLOGY; NONHUMAN; PLANT BIOTECHNOLOGY; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN MODIFICATION; RICE; SUPRAMOLECULAR CHEMISTRY; TRANSGENIC PLANT; TRANSLATION REGULATION;

MAMMALIA;

EID: 4143061287     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-004-0086-4     Document Type: Conference Paper

References (27)

1. Aeschlimann D, Thomazy V (2000) Protein crosslinking in assembly and remodelling of extracellular matrices: the role of transglutaminases. Connect Tiss Res 41: 1-27
2. Chu L, Robinson DK (2001) Industrial choices for protein production by large-scale cell culture. Curr Opin Biotechnol 12: 180-187
3. Claparols IM, Bassie L, Miro B, Del Duca S, Rodrigulz-Montesinos J, Christou P, Serafini-Fracassini D, Capell T (2004) Transgenic rice as a vehicle for the production of the industrial enzyme transglutaminase, Transgenic Res 13: 195-199
4. Collighan R, Cortez J, Griffin M (2002) The biotechnological applications of transglutaminases. Minerva Biotec 14: 143-148
5. De Laurenzi V, Melino G (2001) Gene disruption of tissue transglutaminase. Mol Cell Biol 21: 148-155
6. Del Duca S, Tidu V, Bassi R, Serafini-Fracassini D, Esposito C (1994) Identification of transglutaminase activity and its substrates in isolated chloroplast of Helianthus tuberosus. Planta 193: 283-289
7. Del Duca S, Bergoli AM, Bergamini C, Serafini-Fracassini D (1997) Transglutaminase-catalyzed modification of cytoskeletal proteins by polyamines during the germination of Malus domestica pollen. Sex Plant Reprod 10: 89-95
8. Del Duca S, Allué Creus J, D'Orazi D, Dondini L, Bregoli AM, SerafiniFracassini D (2000) Tuber vegetative stages and cell cycle in Helianthus tuberosus: protein pattern and their modification by spermidine. J Plant Physiol 156: 17-25
9. Del Duca S, Dondini L, Delia Mea M, Muñoz de Rueda P, Serafini-Fracassini D (2000) Factors affecting transglutaminase activity catalysing polyamine conjugation to endogenous substrates in the entire chloroplast. Plant Physiol Biochem 38: 429-439
10. Dondini L, Del Duca S, Dall'Agata L, Bassi R, Gastaldelli M, Della Mea M, Di Sandro A, Claparols I, Serafini-Fracassini D (2003) Suborganellar localisation and effect of light on Helianthus tuberosus chloroplast transglutaminases and their substrates. Planta 217: 84-95
11. Fesus L, Thomazy V, Falus A (1987) Induction and activation of tissue transglutaminase during programmed cell death. FEBS Lett 224: 104-108
12. Fischer R, Emans NJ, Twyman RM, Schillberg S (2003) Molecular farming of industrial proteins in plants. In: Fingerman M, Nagabhushanam R (eds) Recent advances in marine biotechnology, vol 9 (Biomaterials and bioprocessing). Science Publishers Inc., Enfield, NH, pp 279-313
13. Grabarek J, Ardelt B, Kunicki J, Darzynkiewicz Z (2002) Detection of in situ activation of transglutaminase during apoptosis: correlation with the cell cycle phase by multiparameter flow and laser scanning cytometry. Cytometry 49: 83-89
14. Griffin M, Casadio R, Bergamini CM (2002) Transglutaminases: Nature's biological glues. Biochem J 368: 377-396
15. Ho KCh, Quarmby VE, French FS, Wilson EM (1992) Molecular cloning of rat prostate transglutaminase complementary DNA. The major androgen-regulated protein DPI of rat dorsal prostate and coagulating gland. J Biol Chem 267: 12660-12667
16. Kuraishi C, Sakamoto J, Yamazaki K, Susa Y, Kuhura C, Soeda T (1997) Production of restructured meat using microbial transglutaminase without salt or cooking. J Food Sci 62: 488-490
17. 2+-dependent transglutaminase activity in root and leaf tissue of monocotyledoneous and dicotyledoneous plants. Plant Physiol 117: 1115-1123
18. Lorand L, Graham RM (2003) Transglutaminases: cross-linking enzymes with pleiotropic functions. Nature Rev Cell Biol 4: 140-156
19. Margosiak SA, Dharma A, Bruce-Carver MR, Gonzales AP, Louie D, Kuehn GD (1990) Identification of the large subunit of ribulose 1,5-bisphosphate carboxylase/oxygenase as a substrate for transglutaminase in Medicago sativa L. (alfalfa). Plant Physiol 92: 88-96
20. Melino G, Annichiarico-Petruzzelli M, Piredda L, Candi E, Gentile V, Davies PJ, Piacentini M (1994) Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells. Mol Cell Biol 14: 6584-6589
21. Nemes Z, Demeny M, Marekov LN, Fesus L, Steiner PM (2000) Cholesterol-3-sulfate interferes with cornified envelope assembly by diverting transglutaminase 1 activity from the formation of cross links and esters to the hydrolysis of glutamine. J Biol Chem 275: 2636-2646
22. Serafini-Fracassini D, Del Duca S (2002) Biochemistry and function of plant transglutaminases. Minerva Biotech 14: 135-141
23. Serafini-Fracassini D, Del Duca S, Beninati S (1995) Plant transglutaminases. Phytochem 40: 355-365
24. Serafini-Fracassini D, Del Duca S, Monti F, Poli F, Sacchetti G, Bregoli AM, Biondi S, Della Mea M (2000) Transglutaminase activity during senescence and programmed cell death in the corolla of tobacco (Nicotiana tabacum) flowers. Cell Death Diff 9: 309-321
25. Stöger E, Sack M, Perrin Y, Vaquero C, Torres E, Twyman RM, Christou P, Fischer R (2002) Practical considerations for pharmaceutical antibody production in different crop systems. Mol Breeding 9: 149-158
26. Twyman RM, Stöger E, Schillberg S, Christou P, Fischer R (2003) Molecular farming in plants: a technology coming of age? Trends Biotechnol 21: 570-578
27. Votyakova VT, Wallace HM, Dunbar B, Wilson SB (1999) The covalent attachment of polyamines to proteins in plant mitochondria. Eur J Biochem 260: 250-257