Endothelial dysfunction as a cause of erectile dysfunction - Misdiagnosis or misnomer?

Urology

Volumn 64, Issue 2, 2004, Pages 193-194

  Rajfer, Jacob ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTERY DILATATION; CARDIOVASCULAR SYSTEM; DIAGNOSTIC ERROR; EDITORIAL; ERECTILE DYSFUNCTION; HEMODYNAMICS; HUMAN; MYOPATHY; NOMENCLATURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SMOOTH MUSCLE; VASCULAR ENDOTHELIUM;

AGING; ENDOTHELIUM, VASCULAR; HEMORHEOLOGY; HUMANS; HYPERTENSION; IMPOTENCE; MALE; MODELS, BIOLOGICAL; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; PENIS; VASODILATION;

EID: 4143060515     PISSN: 00904295     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.urology.2004.04.048     Document Type: Editorial

References (16)

1. Feldman H.A., Goldstein I., Hatzichristou D.G., et al. Impotence and it medical and psychosocial correlates results of the Massachusetts Male Aging Study. J Urol. 151:1994;54-61
2. Laumann E.O., Paik A., Rosen R.C. Sexual dysfunction in the United States prevalence and predictors. JAMA. 281:1999;537-544
3. Furchgott R.F., Zawadzki J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 288:1980;373-376
4. Cai H., Harrison D.G. Endothelial dysfunction in cardiovascular disease the role of oxidant stress. Circ Res. 87:2000;840-844
5. Behrendt D., Ganz P. Endothelial function from vascular biology to clinical applications. Am J Cardiol. 90:2002;40L-48L
6. Maxwell A.J. Mechanisms of dysfunction of the nitric oxide pathway in vascular diseases. Nitric Oxide. 6:2002;101-124
7. Cartledge J.J., Eardley I., Morrison J.F. Nitric oxide-mediated corpus cavernosal smooth muscle relaxation is impaired in ageing and diabetes. BJU Int. 87:2001;394-401
8. Kim S.C., Kim I.K., Seo K.K., et al. Involvement of superoxide radical in the impaired endothelium-dependent relaxation of cavernous smooth muscle in hypercholesterolemic rabbits. Urol Res. 25:1997;341-346
9. Vernet D., Cai L., Garban H., et al. Reduction of penile nitric oxide synthase in diabetic BB/WOR and BBZ/WOR rats with erectile dysfunction. Endocrinology. 136:1995;5709-5717
10. Kaiser D.R., Billups K., Mason C., et al. Impaired brachial artery endothelium-dependent and -independent vasodilation in men with erectile dysfunction and no other clinical cardiovascular disease. J Am Coll Cardiol. 43:2004;179-184
11. Bank A.J., Kaiser D.R., Rajala S., et al. In vivo human brachial artery elastic mechanics effects of smooth muscle relaxation. Circulation. 100:1999;41-47
12. Intengan H.D., Schiffrin E.L. Structure and mechanical properties of resistance arteries in hypertension role of adhesion molecules and extracellular matrix determinants. Hypertension. 36:2000;312-318
13. Intengan H.D., Schiffrin E.L. Vascular remodeling in hypertension role of apoptosis, inflammation and fibrosis. Hypertension. 38:2001;581-587
14. Jevitch M.J., Khawand N.Y., Vidic B. Clinical significance of ultrastructural findings in the corpora cavernosa of normal and impotent men. J Urol. 143:1990;289-293
15. Ferrini M., Magee T.R., Vernet D., et al. Aging-related expression of inducible nitric oxide synthase and markers of tissue damage in the rat penis. Biol Reprod. 64:2001;974-982
16. Ferrini M.G., Davila H.H., Valente E.G., et al. Aging related induction of inducible nitric oxide synthase is vasculo-protective to the arterial media. Cardiovasc Res. 61:2004;796-805