Neuronal nicotinic ACH receptor antibody in subacute autonomic neuropathy and cancer-related syndromes

Neurology

Volumn 50, Issue 6, 1998, Pages 1806-1813

  Vernino, Steven ^a   Adamski, Jill ^a   Kryzer, Thomas J ^a   Fealey, Robert D ^a   Lennon, Vanda A ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CHOLINERGIC RECEPTOR; RECEPTOR ANTIBODY;

ADULT; AGED; ARTICLE; AUTOIMMUNITY; AUTONOMIC GANGLION; AUTONOMIC NEUROPATHY; BLADDER CARCINOMA; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; DYSAUTONOMIA; EATON LAMBERT SYNDROME; ENCEPHALOMYOPATHY; FEMALE; HUMAN; LUNG SMALL CELL CANCER; MALE; MYASTHENIA GRAVIS; NEUROBLASTOMA; NEUROMUSCULAR TRANSMISSION; PARANEOPLASTIC SYNDROME; PRIORITY JOURNAL; RECTUM CARCINOMA; THYROID CARCINOMA;

EID: 0031798570     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.50.6.1806     Document Type: Article

References (36)

1. Betz H. Ligand-gated ion channels in the brain: the amino acid receptor superfamily. Neuron 1990;5:383-392.
2. Lindstrom J. Neuronal nicotinic acetylcholine receptors. In: Narahashi T, ed. Ion channels. New York: Plenum Press, 1996:377-450.
3. Jacob MH, Berg DK, Lindstrom JM. Shared antigenic determinant between the Electrophorus acetylcholine receptor and a synaptic component on chick ciliary ganglion neurons. Proc-Natl Acad Sci USA 1984;81:3223-3227.
4. Schoepfer R, Halvorsen SW, Conroy WG, Whiting P, Lindstrom J. Antisera against an acetylcholine receptor α3 fusion protein bind to ganglionic but not to brain nicotinic acetylcholine receptors. FEBS Lett 1989;257:393-399.
5. Orr-Urtreger A, Göldner FM, Saeki M, et al. Mice deficient in the α7 neuronal nicotinic acetylcholine receptor lack α-bungarotoxin binding sites and hippocampal fast nicotinic currents. J Neurosci 1997;17:9165-9171.
6. Sciamanna MA, Griesmann GE, Williams CL, Lennon VA. Nicotinic acetylcholine receptors of muscle and neuronal (α7) types co-expressed in a small cell lung carcinoma. J Neurochem 1997;69:2302-2311.
7. Lindstrom JM, Seybold ME, Lennon VA, Whittingham S, Duane DD. Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value. Neurology 1976;26:1054-1059.
8. Drachman DB. Myasthenia gravis. N Engl J Med 1994;330: 1797-1810.
9. Suarez GA, Fealey RD, Camilleri M, Low PA. Idiopathic autonomic neuropathy: clinical, neurophysiologic, and follow-up studies on 27 patients. Neurology 1994;44:1675-1682.
10. Lennon VA, Sas DF, Busk MF, et al. Enteric neuronal autoantibodies in pseudo-obstruction with small cell lung carcinoma. Gastroenterology 1991;100:137-142.
11. Lucchinetti CF, Kimmel DW, Lennon VA. Paraneoplastic and oncological profiles of patients seropositive for type 1 anti-neuronal nuclear autoantibodies. Neurology 1998;50:652-657.
12. Smit A, Vermeulen M, Koelman J, Wieling W. Unusual recovery from acute panautonomic neuropathy after immunoglobulin therapy. Mayo Clin Proc 1997;72:333-335.
13. Bohnen N, Cheshire WP, Lennon VA, Van Den Berg CJ. Plasma exchange improves function in a patient with ANNA-1 seropositive paraneoplastic autonomic neuropathy. Neurology 1997;48:A131. Abstract.
14. Husebye ES, Winqvist O, Sundkvist G, Kampe O, Karlsson FA. Autoantibodies against adrenal medulla in type 1 and type 2 diabetes mellitus: no evidence for an association with autonomic neuropathy. J Intern Med 1996;239:139-146.
15. Lennon VA, Lambert EH. Myasthenia gravis induced by monoclonal antibodies to acetylcholine receptors. Nature 1980;285:238-240.
16. Sano M, Lennon VA. Enzyme immunoassay of anti-human acetylcholine receptor autoantibodies in patients with myasthenia gravis reveals correlation with striational autoantibodies. Neurology 1993;43:573-578.
17. Lukas RJ. Expression of ganglia-type nicotinic acetylcholine receptors and nicotinic ligand binding sites by cells of the IMR-32 human neuroblastoma clonal line. J Pharmacol Exp Ther 1993;265:294-302.
18. Sine SM. Functional properties of human skeletal muscle acetylcholine receptors expressed by the TE671 cell line. J Biol Chem 1988;263:18052-18062.
19. Bruns R, Lawson-Wendling K, Pugsley T. A rapid filtration assay for soluble receptors using polyethylenimine-treated filters. Anal Biochem 1983;132:74-81.
20. Griesmann GE, Lennon VA. Detection of autoantibodies in myasthenia gravis and Lambert-Eaton myasthenic syndrome. In: Rose NR, de Macario EC, Folds JD, Lane HC, Nakamura RM, eds. Manual of clinical and laboratory immunology, 5th ed., ch. 123. Washington, DC: ASM Press, 1997:983-988.
21. Lennon VA. Calcium channel and related paraneoplastic disease autoantibodies. In: Peter JB, Schoenfeld Y, eds. Textbook of autoantibodies. The Netherlands: Elsevier Science Publishers, 1996:139-147.
22. Gerzanich V, Peng X, Wang F, et al. Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors. Mol Pharmacol 1995;48:774-782.
23. Low PA, Caskey PE, Tuck RR, Fealey RD, Dyck PJ. Quantitative sudomotor axon reflex test in normal and neuropathic subjects. Ann Neurol 1983;14:573-580.
24. Isaacs H. A syndrome of continuous muscle-fibre activity. J Neurol Neurosurg Psychiatry 1961;24:319-325.
25. Newsom-Davis J, Mills KR. Immunological associations of acquired neuromyotonia (Isaacs' syndrome). Report of five cases and literature review. Brain 1993;116:453-469.
26. Riche G, Trouillas P, Bady B. Improvement of Isaacs' syndrome after treatment with azathioprine. J Neurol Neurosurg Psychiatry 1995;59:448. Letter.
27. Hart IK, Waters C, Vincent A, et al. Autoantibodies detected to expressed potassium channels are implicated in neuromyotonia. Ann Neurol 1997;41:238-246.
28. Arimura K, Watanabe O, Kitajima I, et al. Antibodies to potassium channels of PC12 in serum of Isaacs' syndrome: Western blot and immunohistochemical studies. Muscle Nerve 1997;20:299-305.
29. Lennon VA. Serological profile of myasthenia gravis and distinction from the Lambert-Eaton myasthenic syndrome. Neurology 1997;48(suppl 5):S23-S27.
30. Lennon VA, Lindstrom JM, Seybold ME. Experimental autoimmune myasthenia: a model of myasthenia gravis in rats and guinea pigs. J Exp Med 1975;141:1365-1375.
31. Appel SH, Almon RR, Levy N. Acetylcholine receptor antibodies in myasthenia gravis. N Engl J Med 1975;293:760-761.
32. Tsuneki H, Kimura I, Dezaki K, et al. Immunohistochemical localization of neuronal nicotinic receptor subtypes at the pre- and postjunctional sites in mouse diaphragm muscle. Neurosci Lett 1995;196:13-16.
33. Lennon VA, Kryzer TJ, Griesmann GE, et al. Calcium-channel antibodies in Lambert-Eaton myasthenic syndrome and other paraneoplastic syndromes. N Engl J Med 1995;332: 1467-1474.
34. Lennon VA, Kryzer TJ. Neuronal calcium channel autoantibodies coexisting with type 1 Purkinje cell cytoplasmic autoantibodies (PCA-1 or "anti-Yo"). Neurology 1998 (in press). Letter.
35. Tzartos SJ, Seybold ME, Lindstrom JM. Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies. Proc Natl Acad Sci USA 1982;79:188-192.
36. Lennon VA, Griesmann GE. Evidence against acetylcholine receptor having a main immunogenic region as target for autoantibodies in myasthenia gravis. Neurology 1989;39:1069-1076.