Antigen cocktails: valid hypothesis or unsubstantiated hope?

Trends in Parasitology

Volumn 24, Issue 4, 2008, Pages 164-167

  Willadsen, Peter ^a  

^a CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN 4D8; ANTIGEN BM86; ANTIGEN BM91; ANTIGEN DBPA; ANTIGEN PFS25; ANTIGEN PFS28; ANTIGEN RS86; CATHEPSIN L; CYTOSOL AMINOPEPTIDASE; OUTER SURFACE PROTEIN OSPA; PARASITE ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; DRUG EFFICACY; DRUG POTENCY; DRUG RESEARCH; FASCIOLIASIS; HUMAN; IMMUNOGENICITY; NONHUMAN; PARASITEMIA; PARASITOSIS; PROTEIN ANALYSIS; VACCINATION; VACCINE PRODUCTION;

ANIMALS; ANTIGENS, PROTOZOAN; HUMANS; PROTOZOAN INFECTIONS; PROTOZOAN INFECTIONS, ANIMAL; PROTOZOAN VACCINES; TREATMENT OUTCOME; VACCINES, SYNTHETIC;

EID: 41349110373     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2008.01.005     Document Type: Article

References (34)

1. Bethony J.M., et al. Vaccines against blood-feeding nematodes of humans and livestock. Parasitology 133 (2006) S63-S79
2. Kedzierski L., et al. Leishmania vaccines: progress and problems. Parasitology 133 (2006) S87-S112
3. McManus D.P.M., and Dalton J.P. Vaccines against the zoonotic trematodes Schistosoma japonicum, Fasciola hepatica and Fasciola gigantica. Parasitology 133 (2006) S43-S61
4. Richie T. High road, low road? Choices and challenges on the pathway to a malaria vaccine. Parasitology 133 (2006) S113-S144
5. Willadsen P. Vaccination against ectoparasites. Parasitology 133 (2006) S9-S25
6. Lightowlers M.W., and Gauci C. Vaccines against cysticercosis and hydatidosis. Vet. Parasitol. 101 (2001) 337-352
7. Lightowlers M.W. Vaccines for the prevention of cysticercosis. Acta Trop. 87 (2003) 129-135
8. Willadsen P., et al. Commercialisation of a recombinant vaccine against Boophilus microplus. Parasitology 110 (1995) S43-S50
9. Valle M.R., et al. Integrated control of Boophilus microplus stocks in Cuba based on vaccination with the anti-tick vaccine Gavac™. Exp. Appl. Acarol. 34 (2004) 375-382
10. Willadsen P. Anti-tick vaccines. Parasitology 129 (2004) S367-S387
11. Emery D.L. Vaccination against worm parasites of animals. Vet. Parasitol. 64 (1996) 31-45
12. Sugino M., et al. A serine proteinase inhibitor (serpin) from ixodid tick Haemaphysalis longicornis: cloning and preliminary assessment of its suitability as a candidate for a tick vaccine. Vaccine 21 (2003) 2844-2851
13. Imamura S., et al. A serine protease inhibitor (serpin) from Haemaphysalis longicornis as an anti-tick vaccine. Vaccine 23 (2005) 1301-1311
14. de la Fuente J., and Kocan K.M. Strategies for development of vaccines for control of ixodid tick species. Parasite Immunol. 28 (2006) 275-283
15. Lightowlers M.W., et al. Taenia saginata: vaccination against cysticercosis in cattle with recombinant oncosphere antigens. Exp. Parasitol. 84 (1996) 330-338
16. Willadsen P., et al. Comparative vaccination of cattle against Boophilus microplus with recombinant antigen Bm86 alone or in combination with recombinant Bm91. Parasite Immunol. 18 (1996) 241-246
17. Duffy P.E., and Kaslow D.C. A novel malaria protein, Pfs28, and Pfs25 are genetially linked and synergistic as falcipaum malaria transmission-blocking vaccines. Infect. Immun. 65 (1997) 1109-1113
18. Darghouth M.A., et al. Vaccination of calves with an attenuated cell line of Theileria annulata and the sporozoite antigen SPAG-1 produces a synergistic effect. Vet. Parasitol. 142 (2006) 54-62
19. Hanson M.S., et al. Evidence for vaccine synergy between Borrelia burgdorferi decorin binding protein A and outer surface protein A in the mouse model of Lyme borreliosis. Infect. Immun. 68 (2000) 6457-6460
20. Rogers W.O. Protection of Rhesus macaques against lethal Plasmodium knowlesi malaria by a heterologous DNA priming and poxvirus boosting immunization regimen. Infect. Immun. 70 (2002) 4329-4335
21. Loukas A., et al. Hookworm vaccines: past, present, and future. Lancet Infect. Dis. 6 (2006) 733-741
22. Imamura S., et al. Two serine protease inhibitors (serpins) that induce a bovine protective immune response against Rhipicephalus appendiculatus ticks. Vaccine 24 (2006) 2230-2237
23. Molano I., et al. A Leishmania infantum multi-component antigenic protein mixed with live BCG confers protection to dogs experimentally infected with L. infantum. Vet. Immunol. Immunopathol. 92 (2003) 1-13
24. Almazán C., et al. Vaccination with recombinant tick antigens for the control of Ixodes scapularis adult infestations. Vaccine 23 (2005) 5294-5298
25. de la Fuente J., et al. Synergistic effect of silencing the expression of tick protective antigens 4D8 and Rs86 in Rhipicephalus sanguineus by RNA interference. Parasitol. Res. 99 (2006) 108-113
26. Piacenza L., et al. Vaccination with cathepsin L proteinases and with leucine aminopeptidase induces high levels of protection against fascioliasis in sheep. Infect. Immun. 67 (1999) 1954-1961
27. Abraham D., et al. Development of a recombinant antigen vaccine against infection with the filarial worm Onchocerca volvulus. Infect. Immun. 69 (2001) 262-270
28. Mendez S., et al. Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine 23 (2005) 3123-3130
29. Wright I.G., et al. The development of a recombinant Babesia vaccine. Vet. Parasitol. 44 (1992) 3-13
30. Hope M., et al. Potential for recombinant Babesia bovis antigens to protect against a highly virulent isolate. Parasite Immunol. 27 (2005) 439-445
31. Tellam R.L., and Bowles W.M. Control of blowfly strike on sheep: current strategies and future prospects. Int. J. Parasitol. 27 (1997) 261-273
32. Willadsen P., and Kemp D.H. Vaccination with 'concealed' antigens for tick control. Parasitol. Today 4 (1988) 196-198
33. Tracey-Patte P.D., et al. Boophilus microplus: passage of bovine immunoglobulins and albumin across the gut of cattle ticks feeding on normal or vaccinated cattle. Res. Vet. Sci. 43 (1987) 287-290
34. Casu R., et al. Antibody-mediated inhibition of the growth of larvae from an insect causing cutaneous myiasis in a mammalian host. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 8939-8944