Feasibility of sonophoretic delivery for effective skin optical clearing

IEEE Transactions on Biomedical Engineering

Volumn 55, Issue 4, 2008, Pages 1432-1437

  Xu, Xiangqun ^a   Zhu, Qiuhong ^a  

^a ZHEJIANG SCI TECH UNIVERSITY   (China)

Author keywords

Enhancement of epidermal permeability; Skin optical learing; Sonophoresis; Ultrasound

Indexed keywords

OPACITY; SKIN; ULTRASONIC REFLECTION; ULTRASONICS; ULTRAVIOLET SPECTROPHOTOMETERS;

EPIDERMAL PERMEABILITY; OPTICAL CLEARING AGENTS; SKIN OPTICAL LEARING; SONOPHORESIS; SONOPHORETIC DELIVERY;

NONINVASIVE MEDICAL PROCEDURES;

GLYCEROL; PROPYLENE GLYCOL;

ARTICLE; FEASIBILITY STUDY; IN VITRO STUDY; LIGHT SCATTERING; NEAR INFRARED SPECTROSCOPY; OPTICS; SKIN FUNCTION; ULTRASOUND; ULTRAVIOLET SPECTROSCOPY;

ANIMALS; DRUG DELIVERY SYSTEMS; ELECTROPORATION; FEASIBILITY STUDIES; LIGHT; PHOTOMETRY; PROPYLENE GLYCOL; SCATTERING, RADIATION; SKIN PHYSIOLOGY; SONICATION; SWINE;

EID: 41149175416     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/TBME.2007.912416     Document Type: Article

References (28)

1. V. V. Tuchin, Optical Clearing of Tissues and Blood. Bellingham, WA: SPIE, 2005, vol. PM 154.
2. R. K. Wang, V. V. Tuchin, X. Xu, and J. B. Elder, "Concurrent enhancement of imaging depth and contrast for optical coherence tomography by hyperosmotic agents," J. Opt. Soc. Amer. B, vol. 18, pp. 948-953, 2001.
3. X. Xu, S. G. Proskurin, R. K. Wang, and J. B. Elder, "Optical clearing in vivo of human skin with hyperosmotic chemicals investigated by optical coherence tomography and near infrared spectroscopy," Proc. SPIE, vol. 5486, pp. 129-135, 2004.
4. M. Khan, B. Choi, and S. Chess et al., "Optical clearing of in vivo human skin: Implications for light-based diagnostic imaging and therapeutics," Lasers Surg. Med., vol. 34, pp. 83-85, 2004.
5. B. Choi, L. Tsu, and E. Chen et al., "Determination of chemical agent optical clearing potential using in vitro human skin," Lasers Surg. Med., vol. 36, pp. 72-75, 2005.
6. P. B. Wells, A. T. Yeh, and J. D. Humphrey, "Influence of glycerol on the mechanical behavior and thermal damage susceptibility of collagenous tissues," IEEE Trans. Biomed. Eng., vol. 53, no. 4, pp. 747-753, Apr. 2006.
7. V. V. Tuchin, "Optical clearing of tissues and blood using the immersion method," J. Phys. D: Appl. Phys., vol. 38, pp. 2497-2518, 2005.
8. P. Karande, A. Jain, and S. Mitragotri, "Discovery of transdermal penetration enhancers by high-throughput screening," Nat. Biotechnol., vol. 22, pp. 192-197, 2004.
9. G. Vargas, F. K. Chan, S. L. Thomsen, and A. J. Welsh, "Use of osmotically active agents to alter optical properties of tissue: Effects on the detected fluorescence signal measured through skin," Lasers Surg. Med., vol. 29, pp. 213-220, 2001.
10. E. I. Galanzha, V. V. Tuchin, A. V. Solovieva, T. V. Stepanova, Q. Luo, and H. Cheng, "Skin backreflectance and microvascular system functioning at the action of osmotic agents," J. Phys. D: Appl. Phys., vol. 36, pp. 1739-1746, 2003.
11. X. Xu and R. K. Wang, "Synergistic effect of hyperosmotic agents on optical clearing of gastric tissue studied with near infrared spectroscopy," Phys. Med. Biol., vol. 49, pp. 457-468, 2004.
12. M. Khan, S. Chess, and B. Choi et al., "Can topically applied optical clearing agents increase the epidermal damage threshold and enhance therapeutic efficacy?," Lasers Surg. Med., vol. 35, pp. 93-95, 2004.
13. J. Jiang and R. K. Wang, "Comparing the synergistic effects of oleic acid and dimethyl sulfoxide as vehicles for optical clearing of skin tissue in vitro," Phys. Med. Biol., vol. 49, pp. 5283-5294, 2004.
14. X. Xu and Q. Zhu, "Evaluation of skin optical clearing enhancement with azone as a penetration enhancer," Opt. Commun., vol. 279, pp. 223-228, 2007.
15. O Stumpp, A. J. Welch, and J. Neev, "Enhancement of transdermal skin clearing agent delivery using a 980 nm diode laser," Lasers Surg. Med., vol. 37, pp. 278-285, 2005.
16. V. V. Tuchin, G. B. Altshuler, and A. A. Gavrilova et al., "Optical clearing of skin using flashlamp-induced enhancement of epidermal permeability," Lasers Surg. Med., vol. 38, pp. 824-836, 2006.
17. T. C. K. Chan, "Percutaneous penetration enhancers: An update," in Proc. 9th Biennial Int. Conf. Percutaneous Penetration, La Grand Motte, France, 2004, pp. 18-22.
18. S. Mitragotri, "Sonophoresis: A 50-year journey," DDT, vol. 9, pp. 735-736, 2004.
19. R. K. Wang, X. Xu, Y. He, and J. B. Elder, "Investigation of optical clearing of gastric tissue immersed with hyperosmotic agents," IEEE J. Sel. Topics Quant. Electron., vol. 9, no. 2, pp. 234-242, Mar./Apr. 2003.
20. X. Xu and L. Wu, "Influence of permeation characteristics of hyperosmotic agents on optical clearing of gastric tissue studied with near-infrared spectroscopy," Chin. J. Lasers, vol. 32, pp. 717-722, 2005.
21. X. Xu and R. K. Wang, "The role of water desorption on optical clearing of biotissues: Studied with near infrared reflectance spectroscopy," Med. Phys., vol. 30, pp. 1246-1253, 2003.
22. X. Xu, R. K. Wang, and J. B. Elder, "Optical clearing effect on gastric tissues immersed with biocompatible chemical agents investigated by near infrared reflectance spectroscopy," J. Phys. D: Appl. Phys., vol. 36, pp. 1707-1713, 2003.
23. I. Lavon, N. Grossman, and J. Kost, "The nature of ultrasound-SLS synergism during enhanced transdermal transport," J. Control. Rel., vol. 107, pp. 484-494, 2005.
24. A. T. Yeh and J. Hirshburg, "Molecular interactions of exogenous chemical agents with collagen-implications for tissue optical clearing," J. Biomed. Opt., vol. 11, p. 014003, 2006.
25. J. Hirshburg, B. Choi, and J. S. Nelson et al., "Collagen solubility correlates with skin optical clearing," J. Biomed. Opt., vol. 11, p. 040501, 2006.
26. C. G. Rylander, O. F. Stumpp, T. E. Milner, N. J. Kemp, J. M. Mendenhall, K. R. Diller, and A. J. Welch, "Dehydration mechanism of optical clearing in tissue," J. Biomed. Opt., vol. 11, p. 041117-1, 2006.
27. S. Mitragotri, "Synergistic effect of enhancers for transdermal drug delivery," Pharm. Res., vol. 17, pp. 1354-1359, 2000.
28. S. Mitragotri and J. Kost, "Low-frequency sonophoresis: A noninvasive method of drug delivery and diagnostics," Biotechnol. Progr., vol. 16, pp. 488-492, 2000.