Permeability changes in response to NONOate and NONOate prodrug derived nitric oxide in a blood-brain barrier model formed by primary porcine endothelial cells

Nitric Oxide - Biology and Chemistry

Volumn 18, Issue 3, 2008, Pages 229-239

  Winter, Sven ^a   Konter, Joerg ^a   Scheler, Stefan ^a   Lehmann, Jochen ^a   Fahr, Alfred ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Blood brain barrier; Diazeniumdiolate; NO donor; NONOate; Permeability; Primary porcine endothelial cells

Indexed keywords

AMINO ACID DERIVATIVE; CARBOXYFLUORESCEIN; METHYLENE BLUE; NITRIC OXIDE; NITRIC OXIDE DONOR; O 2 (4 METHYLBENZEN SULFONYL) 1 (PYRROLIDIN 1 YL)DIAZEN 1 IUM 1,2 DIOLATE; O 2 ETHYL 1 (BUTYLPIPERAZIN 1 YL)DIAZEN 1 IUM 1,2 DIOLATE; O 2 ETHYL 1 (PHENYLPIPERAZIN 1 YL)DIAZEN 1 IUM 1,2 DIOLATE; PRODRUG; SODIUM 1 (N,N DIBUTYLAMINO)DIAZEN 1 IUM 1,2 DIOLATE; SODIUM 1 (PHENYLPIPERAZIN 1 YL)DIAZEN 1 IUM 1,2 DIOLATE; SODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SYNTHESIS; ENDOTHELIUM CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; AZO COMPOUNDS; BLOOD-BRAIN BARRIER; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FLUORESCENT DYES; METHYLENE BLUE; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; NITRIC OXIDE; NITRIC OXIDE DONORS; PERMEABILITY; PRODRUGS; SWINE; TIME FACTORS;

SUS;

EID: 41149164577     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2008.01.006     Document Type: Article

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