Natural chromenes and chromene derivatives as potential anti-trypanosomal agents

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 3, 2008, Pages 538-540

  Batista Jr , João Marcos ^a   Lopes, Adriana Aparecida ^a   Ambrósio, Daniela Luz ^a   Regasini, Luis Octávio ^a   Kato, Massuo Jorge ^b   Bolzani, Vanderlan Da Silva ^a   Cicarelli, Regina Maria Barretto ^a   Furlan, Maysa ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Chromene; Piper aduncum; Piper gaudichaudianum; Piperaceae; Trypanosoma cruzi

Indexed keywords

ANTITRYPANOSOMAL AGENT; BENZNIDAZOLE; CHROMENE DERIVATIVE; METHYL 2 METHYL 8 (3'' METHYLBUT 2'' ENYL) 2 (4' METHYLPENT 3' ENYL)2H CHROMENE 6 CARBOXYLIC ACID; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; DRUG POTENCY; ELECTRON; IC 50; IN VITRO STUDY; METHYLATION; NONHUMAN; PIPERACEAE; TRYPANOSOMA CRUZI;

ANIMALS; BENZOPYRANS; PARASITIC SENSITIVITY TESTS; PIPER; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 41149159074     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.538     Document Type: Article

References (11)

1. Pozas R., Carballo J., Castro C., Rubio J., Bioorg. Med. Chem. Lett., 15, 1417-1421 (2005).
2. del Olmo E., Garcia-Armas M., Lópes-Pérez J. L., Ruiz G., Vargas F., Giménez A., Deharo E., San Feliciano A., Bioorg. Med. Chem. Lett., 11, 2755-2757 (2001).
3. Cunha W. R., Martins C., Ferreira D. S., Crotti A. E. M., Lopes N. P., Albuquerque S., Planta Med., 69, 468-470 (2003).
4. Lago J. H. G., Ramos C. S., Casanova D. C. C., Morandim A. A., Bergamo D. C. B., Cavalheiro A. J., Bolzani V. S., Furlan M., Guimarães E. F., Young M. C. M., Kato M. J., J. Nat. Prod., 67, 1783-1788 (2004).
5. Baldoqui D. C., Kato M. J., Cavalheiro A. J., Bolzani V. S., Young M. C. M., Furlan M., Phytochemistry, 51, 899-902 (1999).
6. Urbansky E. T., Bashe W. J., J. Chromatogr. A, 867, 143-149 (2000).
7. Nozoe T., Tanimoto K., Takemitsu T., Kitamura T., Harada T., Osawa T., Takayasu O., Solid State Ionics, 141, 695-700 (2001).
8. Duan H., Takaishi Y., Momota H., Ohmoto Y., Taki T., Jia Y., Li D., J. Nat. Prod., 64, 582-587 (2001).
9. Orjala J., Eldelmeier C. A. J., Wright A. D., Rali T., Sticher O., Phytochemistry, 34, 813-818 (1993).
10. Diaz P. P., Arias T., Nathan P. J., Phytochemistry, 26, 809-811 (1987).
11. Moreira D. L., Guimarães E. F., Kaplan M. A. C., Phytochemistry, 48, 1075-1077 (1998).