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Volumn 34, Issue 3, 2008, Pages 267-278

Precursor system of liquid crystalline phase containing propolis microparticles for the treatment of periodontal disease: Development and characterization

Author keywords

Intra periodontal pocket drug delivery systems; Periodontal disease; Precursor system of liquid crystalline phase; Propolis microparticles; Propolis release

Indexed keywords

GELATIN; HEXADECANOL; MYRISTIC ACID ISOPROPYL ESTER; PROCETYL AWS; PROPOLIS; SURFACTANT; UNCLASSIFIED DRUG;

EID: 41149155926     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040701655911     Document Type: Article
Times cited : (42)

References (63)
  • 1
    • 0021191677 scopus 로고
    • Comparison of the immediate effects on the subgingival microflora of acrylic strips containing 40% chlorhexidine, metronidazole or tetracycline
    • Addy, M., & Langeroudi, M. (1984). Comparison of the immediate effects on the subgingival microflora of acrylic strips containing 40% chlorhexidine, metronidazole or tetracycline. J. Clin. Periodontol., 11, 379-386.
    • (1984) J. Clin. Periodontol , vol.11 , pp. 379-386
    • Addy, M.1    Langeroudi, M.2
  • 2
    • 3242767747 scopus 로고    scopus 로고
    • Rheological characterisation of primary and binary interactive bioadhesive gels composed of cellulose derivatives designed as ophthalmic viscosurgical devices
    • Andrews, G. P., Gorman, S. P., & Jones, D. S. (2005). Rheological characterisation of primary and binary interactive bioadhesive gels composed of cellulose derivatives designed as ophthalmic viscosurgical devices. Biomaterials, 26, 571-580.
    • (2005) Biomaterials , vol.26 , pp. 571-580
    • Andrews, G.P.1    Gorman, S.P.2    Jones, D.S.3
  • 4
    • 0142091819 scopus 로고    scopus 로고
    • Gelatin microparticles containing propolis obtained by spray-drying technique: Preparation and characterization
    • Bruschi, M. L., Cardoso, M. L. C., Lucchesi, M. B., & Gremião, M. P. D. (2003). Gelatin microparticles containing propolis obtained by spray-drying technique: Preparation and characterization. Int. J. Pharm., 264, 45-55.
    • (2003) Int. J. Pharm , vol.264 , pp. 45-55
    • Bruschi, M.L.1    Cardoso, M.L.C.2    Lucchesi, M.B.3    Gremião, M.P.D.4
  • 5
    • 16244377780 scopus 로고    scopus 로고
    • Oral bioadhesive drug delivery systems
    • Bruschi, M. L., & de Freitas, O. (2005). Oral bioadhesive drug delivery systems. Drug Dev. Ind. Pharm., 31, 293-310.
    • (2005) Drug Dev. Ind. Pharm , vol.31 , pp. 293-310
    • Bruschi, M.L.1    de Freitas, O.2
  • 7
    • 27444434566 scopus 로고    scopus 로고
    • In vitro release of propolis from gelatin microparticles prepared by spray-drying technique
    • Bruschi, M. L., Lopes, R. S., Franco, S. L., & Gremião, M. P. D. (2004). In vitro release of propolis from gelatin microparticles prepared by spray-drying technique. Rev. Ciênc. Farm., 25, 79-84.
    • (2004) Rev. Ciênc. Farm , vol.25 , pp. 79-84
    • Bruschi, M.L.1    Lopes, R.S.2    Franco, S.L.3    Gremião, M.P.D.4
  • 8
    • 33645010971 scopus 로고    scopus 로고
    • Preparation and antimicrobial activity of gelatin microparticles containing propolis against oral pathogens
    • Bruschi, M. L., Martins, C. H. G., Vinholis, A. H. C., Casemiro, L. A., Panzeri, H., Gremião, M. P. D., et al. (2006). Preparation and antimicrobial activity of gelatin microparticles containing propolis against oral pathogens. Drug Dev. Ind. Pharm., 32, 229-238.
    • (2006) Drug Dev. Ind. Pharm , vol.32 , pp. 229-238
    • Bruschi, M.L.1    Martins, C.H.G.2    Vinholis, A.H.C.3    Casemiro, L.A.4    Panzeri, H.5    Gremião, M.P.D.6
  • 9
    • 34548039758 scopus 로고    scopus 로고
    • Recent progress in research of propolis use in periodontology
    • Bruschi, M. L., Panzeri, H., & Lara, E. H. G. (2005). Recent progress in research of propolis use in periodontology. Rev. ABO Nac., 13, 86-91.
    • (2005) Rev. ABO Nac , vol.13 , pp. 86-91
    • Bruschi, M.L.1    Panzeri, H.2    Lara, E.H.G.3
  • 10
    • 0032489791 scopus 로고    scopus 로고
    • Review of the biological properties and toxicity of bee propolis (Propolis)
    • Burdock, G. A. (1998). Review of the biological properties and toxicity of bee propolis (Propolis). Food Chem. Toxicol., 36, 347-363.
    • (1998) Food Chem. Toxicol , vol.36 , pp. 347-363
    • Burdock, G.A.1
  • 11
    • 0029802772 scopus 로고    scopus 로고
    • Medication as risk factors for periodontal disease
    • Ciancio, S. G. (1996). Medication as risk factors for periodontal disease. J. Periodontol., 67(10 suppl.), 1055-1059.
    • (1996) J. Periodontol , vol.67 , Issue.10 SUPPL. , pp. 1055-1059
    • Ciancio, S.G.1
  • 13
    • 0030271509 scopus 로고    scopus 로고
    • Gelatin microspheres: Influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties
    • Esposito, E., Cortesi, R., & Nastruzzi, C. (1996). Gelatin microspheres: Influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties. Biomaterials, 17, 2009-2020.
    • (1996) Biomaterials , vol.17 , pp. 2009-2020
    • Esposito, E.1    Cortesi, R.2    Nastruzzi, C.3
  • 14
    • 0343558535 scopus 로고    scopus 로고
    • Theory of suspensions
    • H. A. Lieberman, M. M. Rieger, & G. S. Banker Eds, New York: Marcel Dekker, Inc
    • Falkiewicz, M. J. (1996). Theory of suspensions. In H. A. Lieberman, M. M. Rieger, & G. S. Banker (Eds.) Pharmaceutical dosage forms: Disperse systems (pp. 17-52). New York: Marcel Dekker, Inc.
    • (1996) Pharmaceutical dosage forms: Disperse systems , pp. 17-52
    • Falkiewicz, M.J.1
  • 15
    • 0026831371 scopus 로고
    • The potential role of controlled-release delivery systems for chemotherapeutic agents in periodontics
    • Fiorellini, J. P., & Paquette, D. W. (1992). The potential role of controlled-release delivery systems for chemotherapeutic agents in periodontics. Curr. Opin. Dent., 2, 63-79.
    • (1992) Curr. Opin. Dent , vol.2 , pp. 63-79
    • Fiorellini, J.P.1    Paquette, D.W.2
  • 16
    • 4444233506 scopus 로고    scopus 로고
    • Experimental designed optimisation and stability evaluation of dry suspensions with artemisinin derivatives for pediatric use
    • Gabriëls, M., & Plaizier-Vercammen, J. (2004). Experimental designed optimisation and stability evaluation of dry suspensions with artemisinin derivatives for pediatric use. Int. J. Pharm., 283, 19-34.
    • (2004) Int. J. Pharm , vol.283 , pp. 19-34
    • Gabriëls, M.1    Plaizier-Vercammen, J.2
  • 17
    • 0141680654 scopus 로고    scopus 로고
    • Buccal delivery systems
    • Hao, J., & Heng, W. S. (2003). Buccal delivery systems. Drug Dev. Ind. Pharm., 29, 821-832.
    • (2003) Drug Dev. Ind. Pharm , vol.29 , pp. 821-832
    • Hao, J.1    Heng, W.S.2
  • 19
    • 0035213275 scopus 로고    scopus 로고
    • Rheological characterization of bioadhesive, antimicrobial, semisolids designed for the treatment of periodontal diseases: Transient and dynamic viscoelastic and continuous shear analysis
    • Jones, D. S., Brown, A. F., & Woolfson, A. D. (2001). Rheological characterization of bioadhesive, antimicrobial, semisolids designed for the treatment of periodontal diseases: Transient and dynamic viscoelastic and continuous shear analysis. J. Pharm. Sci., 90, 1978-1990.
    • (2001) J. Pharm. Sci , vol.90 , pp. 1978-1990
    • Jones, D.S.1    Brown, A.F.2    Woolfson, A.D.3
  • 20
    • 0033050183 scopus 로고    scopus 로고
    • Physicochemical characterization and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis
    • Jones, D. S., Irwin, C. R., Woolfson, A. D., Djokic, J., & Adams, V. (1999). Physicochemical characterization and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis. J. Pharm. Sci., 88, 592-598.
    • (1999) J. Pharm. Sci , vol.88 , pp. 592-598
    • Jones, D.S.1    Irwin, C.R.2    Woolfson, A.D.3    Djokic, J.4    Adams, V.5
  • 21
    • 0036771083 scopus 로고    scopus 로고
    • Examination of the flow rheological and textural properties of polymer gels composed of poly(methylvinylether-co-maleic anhydride) and poly(vinylpyrrolidone): Rheological and mathematical interpretation of textural parameters
    • Jones, D. S., Lawlor, M. S., & Woolfson, A. D. (2002). Examination of the flow rheological and textural properties of polymer gels composed of poly(methylvinylether-co-maleic anhydride) and poly(vinylpyrrolidone): Rheological and mathematical interpretation of textural parameters. J. Pharm. Sci., 91, 2090-2101.
    • (2002) J. Pharm. Sci , vol.91 , pp. 2090-2101
    • Jones, D.S.1    Lawlor, M.S.2    Woolfson, A.D.3
  • 22
    • 0030913693 scopus 로고    scopus 로고
    • Textural analysis and flow rheometry of bioadhesive, antimicrobial oral gels
    • Jones, D. S., Woolfson, A. D., & Brown, A. F. (1997a). Textural analysis and flow rheometry of bioadhesive, antimicrobial oral gels. Pharm. Res., 14, 450-457.
    • (1997) Pharm. Res , vol.14 , pp. 450-457
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3
  • 23
    • 0030955984 scopus 로고    scopus 로고
    • Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers
    • Jones, D. S., Woolfson, A. D., Brown, A. F. (1997b). Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers. Int. J. Pharm., 151, 223-233.
    • (1997) Int. J. Pharm , vol.151 , pp. 223-233
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3
  • 24
    • 0034601173 scopus 로고    scopus 로고
    • Design, characterisation and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease
    • Jones, D. S., Woolfson, A. D., Brown, A. F., Coulter, W. A., Mcclelland, C., & Irwin, C. R. (2000). Design, characterisation and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease. J. Control. Release, 67, 357-368.
    • (2000) J. Control. Release , vol.67 , pp. 357-368
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3    Coulter, W.A.4    Mcclelland, C.5    Irwin, C.R.6
  • 25
    • 0030766318 scopus 로고    scopus 로고
    • Mucoadhesive, syringeable drug delivery systems for controlled application of metronidazole to the periodontal pocket: In vitro release kinetics, syringeability, mechanical and mucoadhesive properties
    • Jones, D. S., Woolfson, A. D., Brown, A. F., & O'Neill, M. J. (1997c). Mucoadhesive, syringeable drug delivery systems for controlled application of metronidazole to the periodontal pocket: In vitro release kinetics, syringeability, mechanical and mucoadhesive properties. J. Control. Release, 49, 71-79.
    • (1997) J. Control. Release , vol.49 , pp. 71-79
    • Jones, D.S.1    Woolfson, A.D.2    Brown, A.F.3    O'Neill, M.J.4
  • 26
    • 0030241089 scopus 로고    scopus 로고
    • Texture profile analysis of bioadhesive polymeric semisolids: Mechanical characterization and investigation of interactions between formulation components
    • Jones, D. S., Woolfson, A. D., & Djokic, J. (1996a). Texture profile analysis of bioadhesive polymeric semisolids: Mechanical characterization and investigation of interactions between formulation components. J. App. Pol. Sci., 61, 2229-2234.
    • (1996) J. App. Pol. Sci , vol.61 , pp. 2229-2234
    • Jones, D.S.1    Woolfson, A.D.2    Djokic, J.3
  • 27
    • 0030469411 scopus 로고    scopus 로고
    • Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases
    • Jones, D. S., Woolfson, A. D., Djokic, J., & Coulter, W. A. (1996b). Development and mechanical characterization of bioadhesive semi-solid, polymeric systems containing tetracycline for the treatment of periodontal diseases. Pharm. Res., 13, 1734-1738.
    • (1996) Pharm. Res , vol.13 , pp. 1734-1738
    • Jones, D.S.1    Woolfson, A.D.2    Djokic, J.3    Coulter, W.A.4
  • 28
    • 1842505298 scopus 로고    scopus 로고
    • Formulation and preliminary in vivo dog studies of a novel drug delivery system for the treatment of periodontitis
    • Kelly, H. M., Deasy, P. B., Ziaka, E., & Claffey, N. (2004). Formulation and preliminary in vivo dog studies of a novel drug delivery system for the treatment of periodontitis. Int. J. Pharm., 274, 167-183.
    • (2004) Int. J. Pharm , vol.274 , pp. 167-183
    • Kelly, H.M.1    Deasy, P.B.2    Ziaka, E.3    Claffey, N.4
  • 29
    • 0034142062 scopus 로고    scopus 로고
    • In vitro antimicrobial activity of propolis and Arnica montana against oral pathogens
    • Koo, H., Gomes, B. P. F. A., Rosalen, P. L., Ambrosano, G. M. B., Park, Y. K., & Cury, J. A. (2000). In vitro antimicrobial activity of propolis and Arnica montana against oral pathogens. Arch. Oral Biol., 45, 141-148.
    • (2000) Arch. Oral Biol , vol.45 , pp. 141-148
    • Koo, H.1    Gomes, B.P.F.A.2    Rosalen, P.L.3    Ambrosano, G.M.B.4    Park, Y.K.5    Cury, J.A.6
  • 31
  • 32
    • 0034999158 scopus 로고    scopus 로고
    • Water quantitatively induces the mucoadhesion of liquid crystalline phases of glyceryl monooleate
    • Lee, J., Young, S. A., & Kellaway, W. (2001). Water quantitatively induces the mucoadhesion of liquid crystalline phases of glyceryl monooleate. J. Pharm. Pharmacol., 53, 629-636.
    • (2001) J. Pharm. Pharmacol , vol.53 , pp. 629-636
    • Lee, J.1    Young, S.A.2    Kellaway, W.3
  • 33
    • 0020595176 scopus 로고
    • Progression of periodontal disease in adult subjects in the absence of periodontal therapy
    • Lindhe, J., Haffajee, A. J., & Socransky, S. S. (1983). Progression of periodontal disease in adult subjects in the absence of periodontal therapy. J. Clin. Periodontol., 10, 433-442.
    • (1983) J. Clin. Periodontol , vol.10 , pp. 433-442
    • Lindhe, J.1    Haffajee, A.J.2    Socransky, S.S.3
  • 34
    • 0021489813 scopus 로고
    • Long-term maintenance of patients treated for advanced periodontal disease
    • Lindhe, J., & Nyman, S. (1984). Long-term maintenance of patients treated for advanced periodontal disease. J. Clin. Periodontol., 11, 504-514.
    • (1984) J. Clin. Periodontol , vol.11 , pp. 504-514
    • Lindhe, J.1    Nyman, S.2
  • 35
    • 0023338640 scopus 로고
    • Nature of periodontal disease: Pathogenic mechanisms
    • Listgarten, M. A. (1987). Nature of periodontal disease: Pathogenic mechanisms. J. Periodontol. Res., 22, 172-178.
    • (1987) J. Periodontol. Res , vol.22 , pp. 172-178
    • Listgarten, M.A.1
  • 36
  • 39
    • 23944435698 scopus 로고    scopus 로고
    • Assessment of the antioxidant activities of Brazilian extracts of propolis alone and in topical pharmaceutical formulations
    • Marquele, F. D., Di Mambro, M., Georgetti, S. R., Casagrande, R., Valim, Y. M. L., & Fonseca, M. J. V. (2005). Assessment of the antioxidant activities of Brazilian extracts of propolis alone and in topical pharmaceutical formulations. J. Pharm. Biom. Anal., 39, 455-462.
    • (2005) J. Pharm. Biom. Anal , vol.39 , pp. 455-462
    • Marquele, F.D.1    Di Mambro, M.2    Georgetti, S.R.3    Casagrande, R.4    Valim, Y.M.L.5    Fonseca, M.J.V.6
  • 41
    • 0028137798 scopus 로고
    • Delivery systems for the administration of drugs to the periodontal pocket
    • Medlicott, N. J., Rathbone, M. J., Tucker, I. G., & Holborow, D. W. (1994). Delivery systems for the administration of drugs to the periodontal pocket. Adv. Drug Deliv. Rev., 13, 181-203.
    • (1994) Adv. Drug Deliv. Rev , vol.13 , pp. 181-203
    • Medlicott, N.J.1    Rathbone, M.J.2    Tucker, I.G.3    Holborow, D.W.4
  • 42
    • 0005041429 scopus 로고    scopus 로고
    • Screening of antibacterial activity of Amaicha del Valle (Tucumán, Argentina) propolis
    • Moreno, M. I. N., Isla, M. I., Cudmani, N. G., Vattuone, M. A., & Sampietro, A. R. (1999). Screening of antibacterial activity of Amaicha del Valle (Tucumán, Argentina) propolis. J. Ethnopharmacol., 68, 97-102.
    • (1999) J. Ethnopharmacol , vol.68 , pp. 97-102
    • Moreno, M.I.N.1    Isla, M.I.2    Cudmani, N.G.3    Vattuone, M.A.4    Sampietro, A.R.5
  • 43
    • 0034807304 scopus 로고    scopus 로고
    • Antioxidative activities of some commercial honeys, royal jelly, and propolis
    • Nagai, T., Sakai, M., Inoue, R., Inoue, H., & Suzuki, N. (2001). Antioxidative activities of some commercial honeys, royal jelly, and propolis. Food Chem., 75, 237-240.
    • (2001) Food Chem , vol.75 , pp. 237-240
    • Nagai, T.1    Sakai, M.2    Inoue, R.3    Inoue, H.4    Suzuki, N.5
  • 44
    • 0018546283 scopus 로고
    • Use of saliva substitute in post-radiation xerostomia
    • Nakamoto, R. Y. (1979). Use of saliva substitute in post-radiation xerostomia. J. Prosthetic. Dent., 42, 539-542.
    • (1979) J. Prosthetic. Dent , vol.42 , pp. 539-542
    • Nakamoto, R.Y.1
  • 45
    • 0026641726 scopus 로고
    • Formulation of a drug delivery system based on a mixture of monoglycerides and triglycerides for use in the treatment of periodontal disease
    • Norling, T., Lading, P., Engstron, S., Larsson, K., Krog, N., & Missen, S. S. (1992). Formulation of a drug delivery system based on a mixture of monoglycerides and triglycerides for use in the treatment of periodontal disease. J. Clin. Periodontol., 19, 687-692.
    • (1992) J. Clin. Periodontol , vol.19 , pp. 687-692
    • Norling, T.1    Lading, P.2    Engstron, S.3    Larsson, K.4    Krog, N.5    Missen, S.S.6
  • 46
    • 3342899402 scopus 로고    scopus 로고
    • Development of local injectable dental gel: The influence of certain additives on physicochemical properties of glycerylmonooleate-based formulations
    • Okonogi, S., Khongkhunthain, S., Bunyaratavej, P., Thusaphorn, T., & Umpriwan, R. (2004). Development of local injectable dental gel: The influence of certain additives on physicochemical properties of glycerylmonooleate-based formulations. Drug Dev. Ind. Pharm., 30, 347-357.
    • (2004) Drug Dev. Ind. Pharm , vol.30 , pp. 347-357
    • Okonogi, S.1    Khongkhunthain, S.2    Bunyaratavej, P.3    Thusaphorn, T.4    Umpriwan, R.5
  • 47
    • 41149100956 scopus 로고    scopus 로고
    • Suspensões
    • L. Lachman, H. A. Lieberman, & J. L. Kanig Eds, Lisbon, Portugal: Calouste Gulbekian Fundation
    • Patel, N. K., Kennon, L., & Levinson, R. S. (2001). Suspensões. In L. Lachman, H. A. Lieberman, & J. L. Kanig (Eds.) Teoria e Prática na Indústria Farmacêutica (pp. 819-854). Lisbon, Portugal: Calouste Gulbekian Fundation.
    • (2001) Teoria e Prática na Indústria Farmacêutica , pp. 819-854
    • Patel, N.K.1    Kennon, L.2    Levinson, R.S.3
  • 48
    • 1542614043 scopus 로고    scopus 로고
    • Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease
    • Perioli, L., Ambrogi, V., Rubini, D., Giovagnoli, S., Ricci, M., Blasi, P., et al. (2004). Novel mucoadhesive buccal formulation containing metronidazole for the treatment of periodontal disease. J. Control. Release, 95, 521-533.
    • (2004) J. Control. Release , vol.95 , pp. 521-533
    • Perioli, L.1    Ambrogi, V.2    Rubini, D.3    Giovagnoli, S.4    Ricci, M.5    Blasi, P.6
  • 49
    • 0042347581 scopus 로고    scopus 로고
    • Production of hot-melt extruded films containing clotrimazole
    • Repka, M. A., Prodduturi, S., & Stodhill, S. P. (2003). Production of hot-melt extruded films containing clotrimazole. Drug Dev. Ind. Pharm, 29, 757-765.
    • (2003) Drug Dev. Ind. Pharm , vol.29 , pp. 757-765
    • Repka, M.A.1    Prodduturi, S.2    Stodhill, S.P.3
  • 50
    • 0023196815 scopus 로고
    • A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices
    • Ritger, P. L., & Peppas, N. A. (1987). A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices. J. Control. Release, 5, 37-42.
    • (1987) J. Control. Release , vol.5 , pp. 37-42
    • Ritger, P.L.1    Peppas, N.A.2
  • 51
    • 0036307198 scopus 로고    scopus 로고
    • Susceptibility of Prevotella intermedia/Prevotella nigrescens (and Porphyromonas gingivalis) to propolis (bee glue) and other antimicrobial agents
    • Santos, F. A., Bastos, E. M. A., Rodrigues, P. H., Uzeda, M., de Carvalho, M. A. R., Farias, L. M., et al. (2002a). Susceptibility of Prevotella intermedia/Prevotella nigrescens (and Porphyromonas gingivalis) to propolis (bee glue) and other antimicrobial agents. Anaerobe, 8, 9-15.
    • (2002) Anaerobe , vol.8 , pp. 9-15
    • Santos, F.A.1    Bastos, E.M.A.2    Rodrigues, P.H.3    Uzeda, M.4    de Carvalho, M.A.R.5    Farias, L.M.6
  • 54
    • 0018596023 scopus 로고
    • Subgingival microflora and periodontal disease
    • Slots, J. (1979). Subgingival microflora and periodontal disease. J. Clin. Periodontol., 6, 351-382.
    • (1979) J. Clin. Periodontol , vol.6 , pp. 351-382
    • Slots, J.1
  • 55
    • 0037049887 scopus 로고    scopus 로고
    • Caffeic acid phenethyl ester inhibits nitric oxide synthase gene expression and enzyme activity
    • Song, Y. S., Park, E., Hur, G. M., Ryu, Y. S., Lee, Y. S., Lee, J.Y., et al. (2002a). Caffeic acid phenethyl ester inhibits nitric oxide synthase gene expression and enzyme activity. Cancer Lett., 175, 53-61.
    • (2002) Cancer Lett , vol.175 , pp. 53-61
    • Song, Y.S.1    Park, E.2    Hur, G.M.3    Ryu, Y.S.4    Lee, Y.S.5    Lee, J.Y.6
  • 56
    • 0036240197 scopus 로고    scopus 로고
    • Ethanol extract of propolis inhibits nitric oxide synthase gene expression and enzyme activity
    • Song, Y. S., Park, E., Hur, G. M., Ryu, Y. S., Kim, Y. M., & Jin, C. (2002b). Ethanol extract of propolis inhibits nitric oxide synthase gene expression and enzyme activity. J. Ethnopharmacol., 80, 155-161.
    • (2002) J. Ethnopharmacol , vol.80 , pp. 155-161
    • Song, Y.S.1    Park, E.2    Hur, G.M.3    Ryu, Y.S.4    Kim, Y.M.5    Jin, C.6
  • 57
    • 0012772121 scopus 로고    scopus 로고
    • Intra-periodontal pocket drug delivery systems
    • M. J. Rathbone Ed, New York: Marcel Dekker, Inc
    • Soskolone, W. A., & Freidman, M. F. (1996). Intra-periodontal pocket drug delivery systems. In M. J. Rathbone (Ed.), Oral mucosal drug delivery (pp. 359-379). New York: Marcel Dekker, Inc.
    • (1996) Oral mucosal drug delivery , pp. 359-379
    • Soskolone, W.A.1    Freidman, M.F.2
  • 58
    • 0026707926 scopus 로고
    • Systemic absorption of metronidazole after application of a metronidazole 25% dental gel
    • Stoltze, K., & Stellfed, M. (1992). Systemic absorption of metronidazole after application of a metronidazole 25% dental gel. J. Clin. Periodontol., 19, 693.
    • (1992) J. Clin. Periodontol , vol.19 , pp. 693
    • Stoltze, K.1    Stellfed, M.2
  • 59
    • 41149133208 scopus 로고    scopus 로고
    • Urban, M. C. C., Bruschi, M. L., Chiavacci, L. A., & Gremião, M. P. D. (2004). Development and physical characterization of non-ionic microemulsions containing PPG-5-Ceteth-20. Surfactants In Solution Symposium, 15.
    • Urban, M. C. C., Bruschi, M. L., Chiavacci, L. A., & Gremião, M. P. D. (2004). Development and physical characterization of non-ionic microemulsions containing PPG-5-Ceteth-20. Surfactants In Solution Symposium, 15.
  • 60
    • 0025794270 scopus 로고
    • Anti-plaque agents: Rationale and prospects for prevention of gingivitis and periodontal disease
    • Van Der Ouderaa, F. J. G. (1991). Anti-plaque agents: Rationale and prospects for prevention of gingivitis and periodontal disease. J. Clin. Periodontol., 18, 447-454.
    • (1991) J. Clin. Periodontol , vol.18 , pp. 447-454
    • Van Der Ouderaa, F.J.G.1
  • 62
    • 0028431621 scopus 로고
    • Bacteria as risk markers for periodontitis
    • Wolff, L., Dahlen, G., & Aeppli, D. (1994). Bacteria as risk markers for periodontitis. J. Periodontol., 65(5 suppl.), 498-510.
    • (1994) J. Periodontol , vol.65 , Issue.5 SUPPL. , pp. 498-510
    • Wolff, L.1    Dahlen, G.2    Aeppli, D.3
  • 63
    • 0034601178 scopus 로고    scopus 로고
    • Rheological, mechanical and membrane penetration properties of novel dual drug systems for percutaneous delivery
    • Woolfson, A. D., Malcon, R. K., Campbell, K., Jones, D. S., & Russell, J. A. (2000). Rheological, mechanical and membrane penetration properties of novel dual drug systems for percutaneous delivery. J. Control. Release, 67, 395-408.
    • (2000) J. Control. Release , vol.67 , pp. 395-408
    • Woolfson, A.D.1    Malcon, R.K.2    Campbell, K.3    Jones, D.S.4    Russell, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.