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Volumn 55, Issue 2, 2008, Pages 357-376

Advances in Hemophilia: Experimental Aspects and Therapy

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; AMINOCAPROIC ACID; ANTIFIBRINOLYTIC AGENT; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 CONCENTRATE; BLOOD CLOTTING FACTOR 8 INHIBITOR; BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9 COMPLEX; BLOOD CLOTTING FACTOR 9 CONCENTRATE; CYTOKINE; DESMOPRESSIN; FIBRIN GLUE; IRON; LIPOSOME; LYSINE DERIVATIVE; MACROGOL; PHOSPHORUS 32; POLYSIALIC ACID; RADIOISOTOPE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; RECOMBINANT BLOOD CLOTTING FACTOR 8; RECOMBINANT BLOOD CLOTTING FACTOR 9; RECOMBINANT PROTEIN; RITUXIMAB; SULFUR; THROMBIN; TRANEXAMIC ACID; VIRUS VECTOR;

EID: 41149147137     PISSN: 00313955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pcl.2008.01.010     Document Type: Review
Times cited : (15)

References (54)
  • 2
    • 0042411064 scopus 로고    scopus 로고
    • Consensus perspectives on prophylactic therapy for haemophilia: summary statement
    • Berntorp E., Astermark J., Bjorkman S., et al. Consensus perspectives on prophylactic therapy for haemophilia: summary statement. Haemophilia 9 Suppl 1 (2003) 1-4
    • (2003) Haemophilia , vol.9 , Issue.SUPPL. 1 , pp. 1-4
    • Berntorp, E.1    Astermark, J.2    Bjorkman, S.3
  • 3
    • 2942544581 scopus 로고    scopus 로고
    • Comparative analysis of clinical trials and evidence-based treatment algorithm in pulmonary arterial hypertension
    • Galiè N., Seeger W., Naeije R., et al. Comparative analysis of clinical trials and evidence-based treatment algorithm in pulmonary arterial hypertension. J Am Coll Cardiol 43 (2004) 81-88
    • (2004) J Am Coll Cardiol , vol.43 , pp. 81-88
    • Galiè, N.1    Seeger, W.2    Naeije, R.3
  • 4
    • 34547757915 scopus 로고    scopus 로고
    • Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia
    • Manco-Johnson M.J., Abshire T.C., Shapiro A.D., et al. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. N Engl J Med 357 6 (2007) 535-544
    • (2007) N Engl J Med , vol.357 , Issue.6 , pp. 535-544
    • Manco-Johnson, M.J.1    Abshire, T.C.2    Shapiro, A.D.3
  • 5
    • 0033028402 scopus 로고    scopus 로고
    • Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized
    • Astermark J., Petrini P., Tengborn L., et al. Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized. Br J Haematol 105 4 (1999) 1109-1113
    • (1999) Br J Haematol , vol.105 , Issue.4 , pp. 1109-1113
    • Astermark, J.1    Petrini, P.2    Tengborn, L.3
  • 6
    • 0031740076 scopus 로고    scopus 로고
    • Radiological and orthopedic score in pediatric hemophilic patients with early and late prophylaxis
    • Funk M., Schmidt H., Escuriola-Ettingshausen C., et al. Radiological and orthopedic score in pediatric hemophilic patients with early and late prophylaxis. Ann Hematol 77 4 (1998) 171-174
    • (1998) Ann Hematol , vol.77 , Issue.4 , pp. 171-174
    • Funk, M.1    Schmidt, H.2    Escuriola-Ettingshausen, C.3
  • 7
    • 0031876988 scopus 로고    scopus 로고
    • When should prophylactic treatment in patients with haemophilia A and B start?-The German experience
    • Kreuz W., Escuriola-Ettingshausen C., Funk M., et al. When should prophylactic treatment in patients with haemophilia A and B start?-The German experience. Haemophilia 4 4 (1998) 413-417
    • (1998) Haemophilia , vol.4 , Issue.4 , pp. 413-417
    • Kreuz, W.1    Escuriola-Ettingshausen, C.2    Funk, M.3
  • 8
    • 0025991991 scopus 로고
    • Prophylaxis with factor concentrates in preventing hemophilic arthropathy
    • Petrini P., Lindvall N., Egberg N., et al. Prophylaxis with factor concentrates in preventing hemophilic arthropathy. Am J Pediatr Hematol Oncol 13 3 (1991) 280-287
    • (1991) Am J Pediatr Hematol Oncol , vol.13 , Issue.3 , pp. 280-287
    • Petrini, P.1    Lindvall, N.2    Egberg, N.3
  • 9
    • 0036529818 scopus 로고    scopus 로고
    • The effects of postponing prophylactic treatment on long-term outcome in patients with severe hemophilia
    • Fischer K., van der Bom J.G., Mauser-Bunschoten E.P., et al. The effects of postponing prophylactic treatment on long-term outcome in patients with severe hemophilia. Blood 99 7 (2002) 2337-2341
    • (2002) Blood , vol.99 , Issue.7 , pp. 2337-2341
    • Fischer, K.1    van der Bom, J.G.2    Mauser-Bunschoten, E.P.3
  • 10
    • 0028004222 scopus 로고
    • A longitudinal study of orthopaedic outcomes for severe factor-VIII-deficient haemophiliacs. The Orthopaedic Outcome Study Group
    • Aledort L.M., Haschmeyer R.H., and Pettersson H. A longitudinal study of orthopaedic outcomes for severe factor-VIII-deficient haemophiliacs. The Orthopaedic Outcome Study Group. J Intern Med 236 4 (1994) 391-399
    • (1994) J Intern Med , vol.236 , Issue.4 , pp. 391-399
    • Aledort, L.M.1    Haschmeyer, R.H.2    Pettersson, H.3
  • 11
    • 0030378002 scopus 로고    scopus 로고
    • Episodic versus prophylactic infusions for hemophilia A: a cost-effectiveness analysis
    • Smith P.S., Teutsch S.M., Shaffer P.A., et al. Episodic versus prophylactic infusions for hemophilia A: a cost-effectiveness analysis. J Pediatr 129 3 (1996) 424-431
    • (1996) J Pediatr , vol.129 , Issue.3 , pp. 424-431
    • Smith, P.S.1    Teutsch, S.M.2    Shaffer, P.A.3
  • 12
    • 0031827002 scopus 로고    scopus 로고
    • Resource utilisation in haemophiliacs treated in Europe: results from the European Study on Socioeconomic Aspects of Haemophilia Care. The European Socioeconomic Study Group
    • Szucs T.D., Offner A., Kroner B., et al. Resource utilisation in haemophiliacs treated in Europe: results from the European Study on Socioeconomic Aspects of Haemophilia Care. The European Socioeconomic Study Group. Haemophilia 4 4 (1998) 498-501
    • (1998) Haemophilia , vol.4 , Issue.4 , pp. 498-501
    • Szucs, T.D.1    Offner, A.2    Kroner, B.3
  • 13
    • 0036862120 scopus 로고    scopus 로고
    • Prophylactic versus on-demand treatment strategies for severe haemophilia: a comparison of costs and long-term outcome
    • Fischer K., van der Bom J.G., Molho P., et al. Prophylactic versus on-demand treatment strategies for severe haemophilia: a comparison of costs and long-term outcome. Haemophilia 8 6 (2002) 745-752
    • (2002) Haemophilia , vol.8 , Issue.6 , pp. 745-752
    • Fischer, K.1    van der Bom, J.G.2    Molho, P.3
  • 14
    • 0034746292 scopus 로고    scopus 로고
    • What factors should influence the dosage and interval of prophylactic treatment in patients with severe haemophilia A and B?
    • Petrini P. What factors should influence the dosage and interval of prophylactic treatment in patients with severe haemophilia A and B?. Haemophilia 7 1 (2001) 99-102
    • (2001) Haemophilia , vol.7 , Issue.1 , pp. 99-102
    • Petrini, P.1
  • 15
    • 0035106558 scopus 로고    scopus 로고
    • Long-term outcome of individualized prophylactic treatment of children with severe haemophilia
    • van den Berg H.M., Fischer K., Mauser-Bunschoten E.P., et al. Long-term outcome of individualized prophylactic treatment of children with severe haemophilia. Br J Haematol 112 3 (2001) 561-565
    • (2001) Br J Haematol , vol.112 , Issue.3 , pp. 561-565
    • van den Berg, H.M.1    Fischer, K.2    Mauser-Bunschoten, E.P.3
  • 16
    • 33646759553 scopus 로고    scopus 로고
    • Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study
    • Feldman B.M., Pai M., Rivard G.E., et al. Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study. J Thromb Haemost 4 6 (2006) 1228-1236
    • (2006) J Thromb Haemost , vol.4 , Issue.6 , pp. 1228-1236
    • Feldman, B.M.1    Pai, M.2    Rivard, G.E.3
  • 17
    • 0036588696 scopus 로고    scopus 로고
    • The use of haemostatic drugs in haemophilia: desmopressin and antifibrinolytic agents
    • Villar A., Jimenez-Yuste V., Quintana M., et al. The use of haemostatic drugs in haemophilia: desmopressin and antifibrinolytic agents. Haemophilia 8 (2002) 189-193
    • (2002) Haemophilia , vol.8 , pp. 189-193
    • Villar, A.1    Jimenez-Yuste, V.2    Quintana, M.3
  • 18
    • 1842300439 scopus 로고    scopus 로고
    • Desmopressin (DDAVP) enhances platelet adhesion to the extracellular matrix of cultured human endothelial cells through increased expression of tissue factor
    • Galves A., Gomez-Ortiz G., Diaz-Ricart M., et al. Desmopressin (DDAVP) enhances platelet adhesion to the extracellular matrix of cultured human endothelial cells through increased expression of tissue factor. Thromb Haemost 77 (1997) 975-980
    • (1997) Thromb Haemost , vol.77 , pp. 975-980
    • Galves, A.1    Gomez-Ortiz, G.2    Diaz-Ricart, M.3
  • 19
    • 33646488990 scopus 로고    scopus 로고
    • Antigenic responses to bovine thrombin exposure during surgery: a prospective study of 309 patients
    • Winterbottom N., Kuo J.M., Nguyen K., et al. Antigenic responses to bovine thrombin exposure during surgery: a prospective study of 309 patients. Journal of Applied Research 2 (2002) 1-11
    • (2002) Journal of Applied Research , vol.2 , pp. 1-11
    • Winterbottom, N.1    Kuo, J.M.2    Nguyen, K.3
  • 20
    • 0030775632 scopus 로고    scopus 로고
    • Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent
    • Bruce M.E., Will R.G., Ironside J.W., et al. Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 389 6650 (1997) 498-501
    • (1997) Nature , vol.389 , Issue.6650 , pp. 498-501
    • Bruce, M.E.1    Will, R.G.2    Ironside, J.W.3
  • 21
    • 34447629499 scopus 로고    scopus 로고
    • A phase 3, randomized, double-blind comparative study of the efficacy and safety of topical recombinant human thrombin and bovine thrombin in surgical hemostasis
    • Chapman W.C., Singla N., Genyk Y., et al. A phase 3, randomized, double-blind comparative study of the efficacy and safety of topical recombinant human thrombin and bovine thrombin in surgical hemostasis. J Am Coll Surg 205 2 (2007 Aug) 256-265
    • (2007) J Am Coll Surg , vol.205 , Issue.2 , pp. 256-265
    • Chapman, W.C.1    Singla, N.2    Genyk, Y.3
  • 22
    • 0036008495 scopus 로고    scopus 로고
    • Recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high responding inhibitors
    • O'Connell N., Mc Mahon C., Smith J., et al. Recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high responding inhibitors. Br J Haematol 116 3 (2002) 632-635
    • (2002) Br J Haematol , vol.116 , Issue.3 , pp. 632-635
    • O'Connell, N.1    Mc Mahon, C.2    Smith, J.3
  • 23
    • 0032725116 scopus 로고    scopus 로고
    • Treatment of patients with factor VIII and IX inhibitors with special focus on the use of recombinant factor VIIa
    • Hedner U. Treatment of patients with factor VIII and IX inhibitors with special focus on the use of recombinant factor VIIa. Thromb Haemost 82 2 (1999) 531-539
    • (1999) Thromb Haemost , vol.82 , Issue.2 , pp. 531-539
    • Hedner, U.1
  • 24
    • 0029946576 scopus 로고    scopus 로고
    • Effects of hemophilia on articulations of children and adults
    • Rodriguez-Merchan E.C. Effects of hemophilia on articulations of children and adults. Clin Orthop Relat Res 328 (1996) 7-13
    • (1996) Clin Orthop Relat Res , Issue.328 , pp. 7-13
    • Rodriguez-Merchan, E.C.1
  • 25
    • 0036125777 scopus 로고    scopus 로고
    • Radionuclide synovectomy for hemophilic arthropathy: a comprehensive review of safety and efficacy and recommendation for a standarized treatment protocol
    • Dunn A.L., Busch M.T., Wyly J.B., et al. Radionuclide synovectomy for hemophilic arthropathy: a comprehensive review of safety and efficacy and recommendation for a standarized treatment protocol. Thromb Haemost 87 (2002) 383-393
    • (2002) Thromb Haemost , vol.87 , pp. 383-393
    • Dunn, A.L.1    Busch, M.T.2    Wyly, J.B.3
  • 26
    • 0036771773 scopus 로고    scopus 로고
    • 32P radiosynoviorthesis in children with hemophilia
    • Manco-Johnson M.J., Nuss R., Lear J., et al. 32P radiosynoviorthesis in children with hemophilia. J Pediatr Hematol Oncol 24 (2002) 534-539
    • (2002) J Pediatr Hematol Oncol , vol.24 , pp. 534-539
    • Manco-Johnson, M.J.1    Nuss, R.2    Lear, J.3
  • 27
    • 41149097587 scopus 로고    scopus 로고
    • Is there an increased risk of cancer associated with radiosynoviorthesis?
    • [abstract 18FP539]
    • Infante-Rivard C., Rivard G., Winikoff R., et al. Is there an increased risk of cancer associated with radiosynoviorthesis?. Haemophilia 12 2 (2006) [abstract 18FP539]
    • (2006) Haemophilia , vol.12 , Issue.2
    • Infante-Rivard, C.1    Rivard, G.2    Winikoff, R.3
  • 28
    • 33750983966 scopus 로고    scopus 로고
    • Basic aspects of inhibitors to factors VIII and IX and the influence of non-genetic risk factors
    • Astermark J. Basic aspects of inhibitors to factors VIII and IX and the influence of non-genetic risk factors. Haemophilia 12 6 (2006) 8-14
    • (2006) Haemophilia , vol.12 , Issue.6 , pp. 8-14
    • Astermark, J.1
  • 29
    • 0032787813 scopus 로고    scopus 로고
    • Incidence of inhibitors in haemophilia A patients-a review of recent studies of recombinant and plasma-derived factor VIII concentrates
    • Scharrer I., Bray G.L., and Neutzling O. Incidence of inhibitors in haemophilia A patients-a review of recent studies of recombinant and plasma-derived factor VIII concentrates. Haemophilia 5 (1999) 145-154
    • (1999) Haemophilia , vol.5 , pp. 145-154
    • Scharrer, I.1    Bray, G.L.2    Neutzling, O.3
  • 30
    • 30344434999 scopus 로고    scopus 로고
    • Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A
    • Goudemand J., Rothschild C., Demiguel V., et al. Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A. Blood 107 1 (2006) 46-51
    • (2006) Blood , vol.107 , Issue.1 , pp. 46-51
    • Goudemand, J.1    Rothschild, C.2    Demiguel, V.3
  • 31
    • 34249711370 scopus 로고    scopus 로고
    • Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study
    • Gouw S.C., van der Bom J.G., Auerswald G., et al. Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study. Blood 109 11 (2007) 4693-4697
    • (2007) Blood , vol.109 , Issue.11 , pp. 4693-4697
    • Gouw, S.C.1    van der Bom, J.G.2    Auerswald, G.3
  • 32
    • 0344776562 scopus 로고
    • Epitope mapping of human FVIII inhibitor antibodies by deletion analysis of FVIII fragments expressed in Escherichia coli
    • Scandella D., de Graaf Mahoney S., Mattingly M., et al. Epitope mapping of human FVIII inhibitor antibodies by deletion analysis of FVIII fragments expressed in Escherichia coli. Proc Natl Acad Sci U S A 85 (1988) 6152-6156
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 6152-6156
    • Scandella, D.1    de Graaf Mahoney, S.2    Mattingly, M.3
  • 33
    • 2542560221 scopus 로고    scopus 로고
    • The role of plasma-derived factor VIII/von Willebrand factor concentrates in the treatment of hemophilia A patients
    • Auerswald G., Spranger T., and Brackmann H.H. The role of plasma-derived factor VIII/von Willebrand factor concentrates in the treatment of hemophilia A patients. Haematologica 88 9 (2003) 16-20
    • (2003) Haematologica , vol.88 , Issue.9 , pp. 16-20
    • Auerswald, G.1    Spranger, T.2    Brackmann, H.H.3
  • 34
    • 0029910889 scopus 로고    scopus 로고
    • Factor VIII inhibitor antibodies with C2 domain specificity are less inhibitory to factor VIII complexed with von Willebrand factor
    • Suzuki T., Arai M., Amano K., et al. Factor VIII inhibitor antibodies with C2 domain specificity are less inhibitory to factor VIII complexed with von Willebrand factor. Thromb Haemost 76 (1996) 749-754
    • (1996) Thromb Haemost , vol.76 , pp. 749-754
    • Suzuki, T.1    Arai, M.2    Amano, K.3
  • 35
    • 0034913420 scopus 로고    scopus 로고
    • Influence of von Willebrand factor on the reactivity of human factor VIII inhibitors with factor VIII
    • Gensana M., Altisent C., Aznar J.A., et al. Influence of von Willebrand factor on the reactivity of human factor VIII inhibitors with factor VIII. Haemophilia 7 (2001) 369-374
    • (2001) Haemophilia , vol.7 , pp. 369-374
    • Gensana, M.1    Altisent, C.2    Aznar, J.A.3
  • 36
    • 0036332175 scopus 로고    scopus 로고
    • von Willebrand factor modulates factor VIII immunogenicity: comparative study of different factor VIII concentrates in a haemophilia A mouse model
    • Behrmann M., Pasi J., Saint-Remy J.M., et al. von Willebrand factor modulates factor VIII immunogenicity: comparative study of different factor VIII concentrates in a haemophilia A mouse model. Thromb Haemost 88 (2002) 221-229
    • (2002) Thromb Haemost , vol.88 , pp. 221-229
    • Behrmann, M.1    Pasi, J.2    Saint-Remy, J.M.3
  • 37
    • 33645986129 scopus 로고    scopus 로고
    • Occurrence of inhibitors in previously untreated or minimally treated patients with haemophilia A after exposure to a plasma-derived solvent-detergent factor VIII concentrate
    • Gringeri A., Monzini M., Tagariello G., et al. Occurrence of inhibitors in previously untreated or minimally treated patients with haemophilia A after exposure to a plasma-derived solvent-detergent factor VIII concentrate. Haemophilia 12 (2006) 128-132
    • (2006) Haemophilia , vol.12 , pp. 128-132
    • Gringeri, A.1    Monzini, M.2    Tagariello, G.3
  • 38
    • 34447287337 scopus 로고    scopus 로고
    • Immune tolerance induction with a high purity von Willebrand factor/VIII complex concentrate in haemophilia A patients with inhibitors at high risk of a poor response
    • Gringeri A., Musso R., Mazzucconi G., et al. Immune tolerance induction with a high purity von Willebrand factor/VIII complex concentrate in haemophilia A patients with inhibitors at high risk of a poor response. Haemophilia 13 (2007) 373-379
    • (2007) Haemophilia , vol.13 , pp. 373-379
    • Gringeri, A.1    Musso, R.2    Mazzucconi, G.3
  • 39
    • 0033230622 scopus 로고    scopus 로고
    • Clinical applications of anti CD 20 antibodies
    • Gopal A.K., and Press O.W. Clinical applications of anti CD 20 antibodies. J Lab Clin Med 134 (1999) 445-450
    • (1999) J Lab Clin Med , vol.134 , pp. 445-450
    • Gopal, A.K.1    Press, O.W.2
  • 40
    • 0035883071 scopus 로고    scopus 로고
    • Rituximab chimeric anti-CD 20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura
    • Stasi R., Pagano A., Stipa E., et al. Rituximab chimeric anti-CD 20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura. Blood 98 (2001) 952-957
    • (2001) Blood , vol.98 , pp. 952-957
    • Stasi, R.1    Pagano, A.2    Stipa, E.3
  • 41
    • 0037926853 scopus 로고    scopus 로고
    • Rituximab for the treatment of refractory autoimmune hemolytic anemia in children
    • Zecca M., Nobili B., Ramenghi U., et al. Rituximab for the treatment of refractory autoimmune hemolytic anemia in children. Blood 101 (2003) 3857-3861
    • (2003) Blood , vol.101 , pp. 3857-3861
    • Zecca, M.1    Nobili, B.2    Ramenghi, U.3
  • 42
    • 33645981947 scopus 로고    scopus 로고
    • Rituximab for congenital haemophiliacs with inhibitors: a Canadian experience
    • Carcao M., St. Louis J., Poon M.C., et al. Rituximab for congenital haemophiliacs with inhibitors: a Canadian experience. Haemophilia 12 (2006) 7-18
    • (2006) Haemophilia , vol.12 , pp. 7-18
    • Carcao, M.1    St. Louis, J.2    Poon, M.C.3
  • 43
    • 33645980622 scopus 로고    scopus 로고
    • Rituximab for adolescents with haemophilia and high titre inhibitors
    • Fox R.A., Neufeld E.J., and Bennett C.M. Rituximab for adolescents with haemophilia and high titre inhibitors. Haemophilia 12 (2006) 218-222
    • (2006) Haemophilia , vol.12 , pp. 218-222
    • Fox, R.A.1    Neufeld, E.J.2    Bennett, C.M.3
  • 44
    • 0022129810 scopus 로고
    • The molecular genetics of hemophilia: blood clotting factors VIII and IX
    • Lawn R.M. The molecular genetics of hemophilia: blood clotting factors VIII and IX. Cell 42 (1985) 405-406
    • (1985) Cell , vol.42 , pp. 405-406
    • Lawn, R.M.1
  • 45
    • 0037330233 scopus 로고    scopus 로고
    • The molecular basis of hemophilia A: genotype-phenotype relationships and inhibitor development
    • Goodeve A.C., and Peake I.R. The molecular basis of hemophilia A: genotype-phenotype relationships and inhibitor development. Semin Thromb Hemost 29 1 (2003) 23-30
    • (2003) Semin Thromb Hemost , vol.29 , Issue.1 , pp. 23-30
    • Goodeve, A.C.1    Peake, I.R.2
  • 46
    • 34247862426 scopus 로고    scopus 로고
    • Gene therapy, bioengineered clotting factors and novel technologies for hemophilia treatment
    • Pierce G.F., Lillicrap D., Pipe S.W., et al. Gene therapy, bioengineered clotting factors and novel technologies for hemophilia treatment. J Thromb Haemost 5 (2007) 901-906
    • (2007) J Thromb Haemost , vol.5 , pp. 901-906
    • Pierce, G.F.1    Lillicrap, D.2    Pipe, S.W.3
  • 47
    • 33746733616 scopus 로고    scopus 로고
    • Gene therapy for hemophilia
    • Ponder K.P. Gene therapy for hemophilia. Curr Opin Hematol 13 5 (2006) 301-307
    • (2006) Curr Opin Hematol , vol.13 , Issue.5 , pp. 301-307
    • Ponder, K.P.1
  • 48
    • 1942521325 scopus 로고    scopus 로고
    • Bioengineering of coagulation factor VIII for improved secretion
    • Miao H.Z., Sirachainan N., Palmer L., et al. Bioengineering of coagulation factor VIII for improved secretion. Blood 103 (2004) 3412-3419
    • (2004) Blood , vol.103 , pp. 3412-3419
    • Miao, H.Z.1    Sirachainan, N.2    Palmer, L.3
  • 49
    • 28244484911 scopus 로고    scopus 로고
    • The promise and challenges of bioengineered recombinant clotting factors
    • Pipe S.W. The promise and challenges of bioengineered recombinant clotting factors. J Thromb Haemost 3 (2005) 1692-1701
    • (2005) J Thromb Haemost , vol.3 , pp. 1692-1701
    • Pipe, S.W.1
  • 50
    • 0017701219 scopus 로고
    • Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol
    • Abuchowski A., van Es T., Palczuk N.C., et al. Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. J Biol Chem 252 (1977) 3578-3581
    • (1977) J Biol Chem , vol.252 , pp. 3578-3581
    • Abuchowski, A.1    van Es, T.2    Palczuk, N.C.3
  • 51
    • 0043261498 scopus 로고    scopus 로고
    • Pegylation: engineering improved biopharmaceuticals for oncology
    • Molineaux G. Pegylation: engineering improved biopharmaceuticals for oncology. Pharmacotherapy 23 (2003) 3S-8S
    • (2003) Pharmacotherapy , vol.23
    • Molineaux, G.1
  • 52
    • 20444503381 scopus 로고    scopus 로고
    • Factor VIII efficient and specific non-covalent binding to PEGylated liposomes enables prolongation of its circulation time and haemostatic efficacy
    • Baru M., Carmel-Goren L., Barenholz Y., et al. Factor VIII efficient and specific non-covalent binding to PEGylated liposomes enables prolongation of its circulation time and haemostatic efficacy. Thromb Haemost 93 (2005) 1061-1068
    • (2005) Thromb Haemost , vol.93 , pp. 1061-1068
    • Baru, M.1    Carmel-Goren, L.2    Barenholz, Y.3
  • 53
    • 17644391325 scopus 로고    scopus 로고
    • Liposomal drug delivery systems-clinical applications
    • Goyal P., Goyal K., Vijaya Kumar S.G., et al. Liposomal drug delivery systems-clinical applications. Acta Pharm 55 (2005) 1-25
    • (2005) Acta Pharm , vol.55 , pp. 1-25
    • Goyal, P.1    Goyal, K.2    Vijaya Kumar, S.G.3
  • 54
    • 33845241302 scopus 로고    scopus 로고
    • Prolonged bleeding-free period following prophylactic infusion of recombinant factor VIII (Kogenate (R) FS) reconstituted with pegylated liposomes
    • Spira J., Ply Ushch O.P., Andreeva T.A., et al. Prolonged bleeding-free period following prophylactic infusion of recombinant factor VIII (Kogenate (R) FS) reconstituted with pegylated liposomes. Blood 108 (2006) 3668-3673
    • (2006) Blood , vol.108 , pp. 3668-3673
    • Spira, J.1    Ply Ushch, O.P.2    Andreeva, T.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.