Class effects of several ACEIs on cadiocyte apoptosis and expression of caspase-3 and Fas/Fasl genes in experimental diabetic rats

Medical Journal of Wuhan University

Volumn 29, Issue 1, 2008, Pages 24-27

  Song, Chenfang ^a   Xiong, Shixi ^a   Yin, Xuéen ^b   Wang, Hairong ^a   Gong, Fei ^a  

^a WUHAN UNIVERSITY   (China)

^b Central Hospital of Ezhou   (China)

Author keywords

ACEI; Cadiocyte apoptosis; Caspase 3; Class effects; Diabetic; Fas FasL; Gene expression

Indexed keywords

EID: 41149146521     PISSN: 16718852     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Li CY, Cao LS, Zeng QT, et al. Taurine may prevent diabetic rats from developing cardiomyopathy also by downregulating angiotensin II type 2 receptor expression [J]. Cardiovascular Drugs and Therapy,2005,19 (2) : 105-112 .
2. Chinese source
3. Vaur L, Gueret P, Lievre M, et al. Development of congestive heart failure in type 2 diabetic patients with microalbuminuria or proteinuria: observations from the DIABHYCAR(type 2 Diabetes, Hypertension, Cardiovascular Events and Ramipril) study[J]. Diabetes Care, 2003, 26 : 855-860.
4. Fiordaliso F, Li B, Latini R, et al. Myocyte death in streptozotocin-induce diabetes in rats angiotensin II dependent[J]. Laboratory Investigation, 2000,80 : 513-527.
5. Frustaci A, Kajstura J, Chimenti Cet al. Myocardial cell death in human diabetes [J]. Circ Res, 2000, 87 (12) : 1 123-1 132.
6. Xie ZL, Loyama T, Abe K. Effects of an angiotensin-converting enzyme inhibition on the expression of Fas protein and on apoptosis in rat ventricles subjected to reperfusion after ischemia[J]. Curr Ther Res,2000,61 (6) : 358-362.
7. Kobara M,Tatsumi T, Kambayashi D,et al. Effects of ACE inhibition on myocardial apoptosis in an ischemia-reperfusion rat heart mode[J]. Cardiovascular Pharmacol, 2003,41(6) : 880-883.