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Volumn 51, Issue 4, 2008, Pages 694-695

Diabetes therapy by lentiviral hepatic insulin gene expression without transformation of liver

Author keywords

Gene therapy; Hepatocytes; Insulin production; Lentiviral vector; Rat; Type 1 diabetes

Indexed keywords

GLUCAGON; HISTIDINE; HOMEODOMAIN PROTEIN; INSULIN DERIVATIVE; INSULIN[B10 ASPARTIC ACID]; LENTIVIRUS VECTOR; NEUROGENIC DIFFERENTIATION FACTOR; SOMATOSTATIN; STREPTOZOCIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

EID: 41149143064     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-008-0931-1     Document Type: Letter
Times cited : (8)

References (7)
  • 1
    • 34547701718 scopus 로고    scopus 로고
    • Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy
    • Ren B, O'Brien BA, Swan MA et al (2007) Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy. Diabetologia 50:1910-1920
    • (2007) Diabetologia , vol.50 , pp. 1910-1920
    • Ren, B.1    O'Brien, B.A.2    Swan, M.A.3
  • 2
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • Dull T, Zufferey R, Kelly M et al (1998) A third-generation lentivirus vector with a conditional packaging system. J Virol 72:8463-8471
    • (1998) J Virol , vol.72 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3
  • 3
    • 0031743608 scopus 로고    scopus 로고
    • Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
    • Zufferey R, Dull T, Mandel RJ et al (1998) Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 72:9873-9880
    • (1998) J Virol , vol.72 , pp. 9873-9880
    • Zufferey, R.1    Dull, T.2    Mandel, R.J.3
  • 4
    • 0028064783 scopus 로고
    • Genetically engineered proinsulin constitutively processed and secreted as mature, active insulin
    • Groskreutz DJ, Sliwkowski MX, Gorman CM (1994) Genetically engineered proinsulin constitutively processed and secreted as mature, active insulin. J Biol Chem 269:6241-6245
    • (1994) J Biol Chem , vol.269 , pp. 6241-6245
    • Groskreutz, D.J.1    Sliwkowski, M.X.2    Gorman, C.M.3
  • 5
    • 0025990972 scopus 로고
    • Receptor binding and tyrosine kinase activation by insulin analogues with extreme affinities studied in human hepatoma HepG2 cells
    • Drejer K, Kruse V, Larsen UD, Hougaard P, Bjorn S, Gammeltoft S (1991) Receptor binding and tyrosine kinase activation by insulin analogues with extreme affinities studied in human hepatoma HepG2 cells. Diabetes 40:1488-1495
    • (1991) Diabetes , vol.40 , pp. 1488-1495
    • Drejer, K.1    Kruse, V.2    Larsen, U.D.3    Hougaard, P.4    Bjorn, S.5    Gammeltoft, S.6
  • 6
    • 0030614323 scopus 로고    scopus 로고
    • ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: Evidence for enhanced interactions with the insulin-like growth factor-I receptor
    • Milazzo G, Sciacca L, Papa V, Goldfine ID, Vigneri R (1997) ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: evidence for enhanced interactions with the insulin-like growth factor-I receptor. Mol Carcinog 18:19-25
    • (1997) Mol Carcinog , vol.18 , pp. 19-25
    • Milazzo, G.1    Sciacca, L.2    Papa, V.3    Goldfine, I.D.4    Vigneri, R.5
  • 7
    • 0029074618 scopus 로고
    • A transgene coding for a human insulin analog has a mitogenic effect on murine embryonic beta cells
    • Vincent MT, Carroll RJ, Hammer RE et al (1995) A transgene coding for a human insulin analog has a mitogenic effect on murine embryonic beta cells. Proc Natl Acad Sci USA 92:6239-6243
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6239-6243
    • Vincent, M.T.1    Carroll, R.J.2    Hammer, R.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.