Effects of novelty on rats' responses to CO2 exposure

Applied Animal Behaviour Science

Volumn 111, Issue 1-2, 2008, Pages 183-194

  Niel, Lee ^a   Kirkden, Richard D ^a   Weary, Daniel M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Avoidance; Carbon dioxide; Euthanasia; Novelty; Preference; Rats

Indexed keywords

CARBON DIOXIDE; ESCAPE BEHAVIOR; POLLUTION EXPOSURE; RODENT;

MENTHA X PIPERITA; RATTUS; RATTUS NORVEGICUS;

EID: 41149135798     PISSN: 01681591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.applanim.2007.06.004     Document Type: Article

References (28)

1. Ambrose N., Wadham J., and Morton D. Refinement in Euthanasia. In: Balls M., van Zeller A.M., and Halder M.E. (Eds). Progress in the Reduction, Refinement and Replacement of Animal Experimentation (2000), Elsevier Science, Amsterdam 1159-1169
2. CO2 in ventilated humans. J. Appl. Physiol. 81 (1996) 949-956
3. Cain W.S., and Murphy C.L. Interaction between chemoreceptive modalities of odour and irritation. Nature 284 (1980) 255-257
4. 2 stimulation of the cornea: a comparison between human sensation and nerve activity in polymodal nociceptive afferents of the cat. Eur. J. Neurosci. 7 (1995) 1154-1163
5. Coenen A.M., Drinkenburg W.H., Hoenderken R., and van Luijtelaar G.L. Carbon dioxide euthanasia in rats: oxygen supplementation minimizes signs of agitation and asphyxia. Lab. Anim. 29 (1995) 262-268
6. Cooper J., Mason G., and Raj M. Determination of the aversion of farmed mink (Mustela vison) to carbon dioxide. Vet. Rec. 143 (1998) 359-361
7. 2 and maximal voluntary hyperventilation. Am. J. Physiol. 149 (1947) 43-51
8. Dubovicky M., Skultetyova I., and Jezova D. Neonatal stress alters habituation of exploratory behaviour in adult male but not female rats. Pharmacol. Biochem. Behav. 64 (1999) 681-686
9. 2. Invest. Ophthmol. Vis. Sci. 44 (2003) 529-532
10. Gerritzen M.A., Lambooij E., Hillebrand S.J.W., Lanhaar J.A.C., and Pieterse C. Behavioral responses of broilers to different gaseous atmospheres. Poult. Sci. 79 (2000) 928-933
11. Lai Y.L., Lamm W.J.E., and Hildebrandt J. Ventilation during prolonged hypercapnia in the rat. J. Appl. Physiol. 51 (1981) 78-83
12. Leach M.C., Bowell V.A., Allan T.F., and Morton D.B. Aversion to gaseous euthanasia agents in rats and mice. Comparative Med. 52 (2002) 249-257
13. Liotti M., Brannan S., Egan G., Shade R., Madden L., Abplanalp B., Robillard R., Lancaster J., Zamarripa F.E., Fox P.T., and Denton D. Brain responses associated with consciousness of breathlessness (air hunger). Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 2035-2040
14. Mitchell G.S., and Johnson S.M. Neuroplasticity in respiratory motor control. J. Appl. Physiol. 94 (2003) 358-374
15. Montgomery K.C. The relation between fear induced by novel stimulation and exploratory behavior. J. Comp. Physiol. Psychol. 48 (1955) 254-260
16. Niel L., and Weary D.M. Behavioural responses of rats to gradual-fill carbon dioxide euthanasia and reduced oxygen concentrations. Appl. Anim. Behav. Sci. 100 (2006) 295-308
17. Niel L., and Weary D.M. Rats avoid exposure to carbon dioxide and argon. Appl. Anim. Behav. Sci. 107 (2007) 100-109
18. Peppel P., and Anton F. Responses of rat medullary dorsal horn neurons following intranasal noxious chemical stimulation: effects of stimulus intensity, duration, and interstimulus interval. J. Neurophysiol. 70 (1993) 2260-2275
19. Raj A.B.M. Aversive reactions of turkeys to argon, carbon dioxide and a mixture of carbon dioxide and argon. Vet. Rec. 138 (1996) 592-593
20. Raj A.B.M., and Gregory N.G. Welfare implications of the gas stunning of pigs 1. Determination of aversion to initial inhalation of carbon dioxide or argon. Anim. Welfare 4 (1995) 273-280
21. Smith W., and Harrap S.B. Behavioural and cardiovascular responses of rats to euthanasia using carbon dioxide gas. Lab. Anim. 31 (1997) 337-346
22. Sokal R.R., and Rohlf F.J. Biometry: the principles and practice of statistics in biological research (1995), Freeman, New York pp. 728-732
23. 2. Brain Res. 942 (2002) 79-86
24. Wallace K.J., and Rosen J.B. Predator odor as an unconditioned fear stimulus in rats: elicitation of freezing by trimethylthiazoline, a component of fox feces. Behav. Neurosci. 114 (2000) 912-922
25. Waters K.A., and Tinworth K.D. Depression of ventilatory responses after daily cyclic hypercapnic hypoxia in piglets. J. Appl. Physiol. 90 (2001) 1065-1073
26. Webster A.B., and Fletcher D.L. Assessment of the aversion of hens to different gas atmospheres using an approach-avoidance test. Appl. Anim. Behav. Sci. 88 (2004) 275-287
27. Youngentob S.L., Hornung D.E., and Mozell M.M. Determination of carbon dioxide detection thresholds in trained rats. Physiol. Behav. 49 (1991) 21-26
28. Zangrossi H., and File S.E. Behavioral consequences in animal tests of anxiety and exploration of exposure to cat odor. Brain Res. Bull. 29 (1992) 381-388