Synthesis of γ-glutamylcysteine as a major low-molecular-weight thiol in lactic acid bacteria Leuconostoc spp.

Biochemical and Biophysical Research Communications

Volumn 369, Issue 4, 2008, Pages 1047-1051

  Kim, Eun Kyoung ^a   Cha, Chang Jun ^b   Cho, Yong Joon ^a   Cho, Yoo Bok ^a   Roe, Jung Hye ^a  

^a Seoul National University   (South Korea)

^b Chung Ang University   (South Korea)

Author keywords

Glutamylcysteine; Lactic acid bacteria; Low molecular weight thiol; Oxidative stress

Indexed keywords

GAMMA GLUTAMYLCYSTEINE; GLUTATHIONE; GLUTATHIONE SYNTHASE; HYDROGEN PEROXIDE; MESSENGER RNA; THIOL;

ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; GENE SEQUENCE; GSHA GENE; GSHB GENE; LACTIC ACID BACTERIUM; LEUCONOSTOC; LEUCONOSTOC KIMCHII; LEUCONOSTOC MESENTEROIDES; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SYNTHESIS; TRANSCRIPTION INITIATION SITE;

ASPERGILLUS NUCLEASE S1; BACTERIAL PROTEINS; DIPEPTIDES; GENE EXPRESSION; GENES, BACTERIAL; GLUTAMATE-CYSTEINE LIGASE; HYDROGEN PEROXIDE; LACTIC ACID; LEUCONOSTOC; MOLECULAR WEIGHT; OXIDATIVE STRESS; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SULFHYDRYL COMPOUNDS; TRANSCRIPTION INITIATION SITE;

LEUCONOSTOC; LEUCONOSTOC KIMCHII; LEUCONOSTOC MESENTEROIDES;

EID: 41149109973     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.02.139     Document Type: Article

References (26)

1. Meister A., and Anderson M.E. Glutathione. Ann. Rev. Biochem. 52 (1983) 711-760
2. Huang C.S., Moore W.R., and Meister A. On the active site thiol of γ-glutamylcysteine synthetase: relationships to catalysis, inhibition, and regulation. Proc. Natl. Acad. Sci. USA 85 (1988) 2464-2468
3. Meister A. Glutathione metabolism and its selective modification. J. Biol. Chem. 263 (1988) 17205-17208
4. Newton G.L., and Fahey R.C. Determination of biothiols by bromobimane labeling and high-performance liquid chromatography. Methods Enzymol. 251 (1995) 148-166
5. Newton G.L., Arnold K., Price M.S., Sherrill C., Delcardayre S.B., Cohen G., Davies J., Fahey R.C., and Davis C. Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes. J. Bacteriol. 178 (1996) 1990-1995
6. Park J.H., Cha C.J., and Roe J.H. Identification of genes for mycothiol biosynthesis in Streptomyces coelicolor A3(2). J. Microbiol. 44 (2006) 121-125
7. Copley S.D., and Dhillon J.K. Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes. Genome Biol. 3 (2002) research0025.1-0025.16
8. Sherrill C., and Fahey R.C. Import and metabolism of glutathione by Streptococcus mutans. J. Bacteriol. 6 (1998) 1454-1459
9. Gopal S., Borovok I., Ofer A., Yanku M., Cohen G., Goebel W., Kreft J., and Aharonowitz Y. A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis. J. Bacteriol. 187 (2005) 3839-3847
10. Janowiak B.E., and Griffith O.W. Glutathione synthesis in Streptococcus agalactiae. J. Biol. Chem. 280 (2005) 11829-11839
11. Kim J., Chun J., and Han H.U. Leucocostoc kimchii sp. nov., a new species from kimchi. Int. J. Syst. Evol. Microbiol. 50 (2000) 1915-1919
12. Altschul S.F., and Koonin E.V. Iterated profile searches with PSI-BLAST-a tool for discovery in protein databases. Trends Biochem. Sci. 23 (1998) 444-447
13. Schmitt M.E., Brown T.A., and Trumpower B.L. A rapid and simple method for preparation RNA for Saccharomyces cerevisiae. Nucleic Acids Res. 18 (1990) 3091-3092
14. Cho Y.H., Lee E.J., Ahn B.E., and Roe J.H. SigB, an RNA polymerase sigma factor required for osmoprotection and proper differentiation of Streptomyces coelicolor. Mol. Microbiol. 42 (2001) 205-214
15. Newton G.L., and Javor C. γ-Glutamylcysteine and thiosulfate are the major low-molecular-weight thiols in halobacteria. J. Bacteriol. 161 (1985) 438-441
16. Sundquist A.R., and Fahey R.C. The function of γ-glutamylcysteine and bis-γ-glutamylcystine reductase in Halobacterium halobium. J. Biol. Chem. 264 (1989) 719-725
17. Apontowell P., and Berends W. Glutathione biosynthesis in Escherichia coli K12. Properties of the enzymes and regulation. Biochim. Biophys. Acta 399 (1975) 1-9
18. Fahey R.C., Brown W.C., Adams W.B., and Worsham M.B. Occurrence of glutathione in bacteria. J. Bacteriol. 133 (1978) 1126-1129
19. Wiggs J.L., Bush J.W., and Chamberlin M.J. Utilization of promoter and terminator sites on bacteriophage T7 DNA by RNA polymerases from a variety of bacterial orders. Cell 16 (1979) 97-109
20. A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA. Nucleic Acids Res. 23 (1995) 2351-2360
21. Neubauer H., Bauche A., and Mollet B. Molecular characterization and expression analysis of the dextransucrase DsrD of Leuconostoc mesenteroides Lcc4 in homologous and heterologous Lactococcus lactis cultures. Microbiology 149 (2003) 973-982
22. Fernandes L., and Steele J.L. Glutathione content of lactic acid bacteria. J. Dairy Sci. 76 (1993) 1233-1242
23. Li Y., Hugenholtz J., Abee T., and Molenaar D. Glutathione protects Lactococcus lactis against oxidative stress. Appl. Environ. Microbiol. 69 (2003) 5739-5745
24. Zhang J., Fu R.Y., Hugenholtz J., Li Y., and Chen J. Glutathione protects Lactococcus lactis against acid stress. Appl. Environ. Microbiol. 73 (2007) 5268-5275
25. Fuchs J.A., and Warner H.R. Isolation of an Escherichia coli mutant deficient in glutathione synthesis. J. Bacteriol. 124 (1975) 140-148
26. Grant C.M., H Maclver F., and Dawes I.W. Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide γ-glutamylcysteine. Mol. Biol. Cell 8 (1997) 1699-1707