Evidence that human cartilage and chondrocytes do not express calcitonin receptor

Osteoarthritis and Cartilage

Volumn 16, Issue 4, 2008, Pages 450-457

  Lin, Z ^a   Pavlos, N J ^a   Cake, M A ^b   Wood, D J ^a   Xu, J ^a   Zheng, M H ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b MURDOCH UNIVERSITY   (Australia)

Author keywords

Calcitonin; Cartilage; Chondrocyte; Osteoarthritis; Subchondral bone

Indexed keywords

AGGRECAN; CALCITONIN; CALCITONIN RECEPTOR; COLLAGEN TYPE 2; COLLAGENASE 3; CYCLIC AMP; FORSKOLIN; INTERSTITIAL COLLAGENASE; MESSENGER RNA; SALCATONIN; STROMELYSIN;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL STIMULATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HORMONE ACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; OSTEOCLAST; OSTEOLYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTECTION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BONE DENSITY CONSERVATION AGENTS; CALCITONIN; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; CYCLIC AMP; GENE EXPRESSION; HUMANS; IMMUNOASSAY; RECEPTORS, CALCITONIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SALMON;

EID: 41149093144     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2007.08.003     Document Type: Article

References (32)

1. Friedman J., and Raisz L.G. Thyrocalcitonin: inhibitor of bone resorption in tissue culture. Science 150 (1965) 1465-1467
2. Raisz L.G., and Niemann I. Early effects of parathyroid hormone and thyrocalcitonin on bone in organ culture. Nature 214 (1967) 486-487
3. Warshawsky H., Goltzman D., Rouleau M.F., and Bergeron J.J. Direct in vivo demonstration by radioautography of specific binding sites for calcitonin in skeletal and renal tissues of the rat. J Cell Biol 85 (1980) 682-694
4. Pondel M. Calcitonin and calcitonin receptors: bone and beyond. Int J Exp Pathol 81 (2000) 405-422
5. Manicourt D.H., Devogelaer J.P., Azria M., and Silverman S. Rationale for the potential use of calcitonin in osteoarthritis. J Musculoskelet Neuronal Interact 5 (2005) 285-293
6. Karsdal M.A., Tanko L.B., Riis B.J., Sondergard B.C., Henriksen K., Altman R.D., et al. Calcitonin is involved in cartilage homeostasis: is calcitonin a treatment for OA?. Osteoarthritis Cartilage 14 (2006) 617-624
7. Badurski J., Jeziernicka E., Naruszewicz K., and Racewicz A. Comparative analysis of three treatment regimens for treating gonarthritis with calcitonin, naproxen and flavonoids based on EULAR criteria and visual analogue scale (VAS). Pol Tyg Lek 50 (1995) 37-40
8. Punzi L., Schiavon F., Cavasin F., Ramonda R., Gambari P.F., and Todesco S. The influence of intra-articular hyaluronic acid on PGE2 and cAMP of synovial fluid. Clin Exp Rheumatol 7 (1989) 247-250
9. Bagger Y.Z., Tanko L.B., Alexandersen P., Karsdal M.A., Olson M., Mindeholm L., et al. Oral salmon calcitonin induced suppression of urinary collagen type II degradation in postmenopausal women: a new potential treatment of osteoarthritis. Bone 37 (2005) 425-430
10. Manicourt D.H., Azria M., Mindeholm L., Thonar E.J., and Devogelaer J.P. Oral salmon calcitonin reduces Lequesne's algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. Arthritis Rheum 54 (2006) 3205-3211
11. Papaioannou N.A., Triantafillopoulos I.K., Khaldi L., Krallis N., Galanos A., and Lyritis G.P. Effect of calcitonin in early and late stages of experimentally induced osteoarthritis. A histomorphometric study. Osteoarthritis Cartilage 15 (2007) 386-395
12. Sondergaard B.C., Wulf H., Henriksen K., Schaller S., Oestergaard S., Qvist P., et al. Calcitonin directly attenuates collagen type II degradation by inhibition of matrix metalloproteinase expression and activity in articular chondrocytes. Osteoarthritis Cartilage 14 (2006) 759-768
13. Deshmukh K., Kline W.G., and Sawyer B.D. Effects of calcitonin and parathyroid hormone on the metabolism of chondrocytes in culture. Biochim Biophys Acta 499 (1977) 28-35
14. Lyritis G., and Boscainos P.J. Calcitonin effects on cartilage and fracture healing. J Musculoskelet Neuronal Interact 2 (2001) 137-142
15. Ishikawa Y., Wu L.N., Genge B.R., Mwale F., and Wuthier R.E. Effects of calcitonin and parathyroid hormone on calcification of primary cultures of chicken growth plate chondrocytes. J Bone Miner Res 12 (1997) 356-366
16. Franchimont P., Bassleer C., Henrotin Y., Gysen P., and Bassleer R. Effects of human and salmon calcitonin on human articular chondrocytes cultivated in clusters. J Clin Endocrinol Metab 69 (1989) 259-266
17. Di Nino D.L., and Linsenmayer T.F. Positive regulation of endochondral cartilage growth by perichondrial and periosteal calcitonin. Endocrinology 144 (2003) 1979-1983
18. Burch W.M., and Corda G. Calcitonin stimulates maturation of mammalian growth plate cartilage. Endocrinology 116 (1985) 1724-1728
19. Burch W.M. Calcitonin stimulates growth and maturation of embryonic chick pelvic cartilage in vitro. Endocrinology 114 (1984) 1196-1202
20. Hellio M.P., Peschard M.J., Cohen C., Richard M., and Vignon E. Calcitonin inhibits phospholipase A2 and collagenase activity of human osteoarthritic chondrocytes. Osteoarthritis Cartilage 5 (1997) 121-128
21. Huang L., Xu J., Wood D.J., and Zheng M.H. Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formation. Am J Pathol 156 (2000) 761-767
22. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 (2001) 402-408
23. Kuestner R.E., Elrod R.D., Grant F.J., Hagen F.S., Kuijper J.L., Matthewes S.L., et al. Cloning and characterization of an abundant subtype of the human calcitonin receptor. Mol Pharmacol 46 (1994) 246-255
24. Gorn A.H., Lin H.Y., Yamin M., Auron P.E., Flannery M.R., Tapp D.R., et al. Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line. J Clin Invest 90 (1992) 1726-1735
25. Xu J., Wang C., Han R., Pavlos N., Phan T., Steer J.H., et al. Evidence of reciprocal regulation between the high extracellular calcium and RANKL signal transduction pathways in RAW cell derived osteoclasts. J Cell Physiol 202 (2005) 554-562
26. Jones D.G., and Smith R.L. Stimulation of adult chondrocyte metabolism by a thyroid-derived factor. J Orthop Res 8 (1990) 227-233
27. McLatchie L.M., Fraser N.J., Main M.J., Wise A., Brown J., Thompson N., et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393 (1998) 333-339
28. Badurski J.E., Schwamm W., Popko J., Zimnoch L., Rogowski F., and Pawlica J. Chondroprotective action of salmon calcitonin in experimental arthropathies. Calcif Tissue Int 49 (1991) 27-34
29. Behets C., Williams J.M., Chappard D., Devogelaer J.P., and Manicourt D.H. Effects of calcitonin on subchondral trabecular bone changes and on osteoarthritic cartilage lesions after acute anterior cruciate ligament deficiency. J Bone Miner Res 19 (2004) 1821-1826
30. El Hajjaji H., Williams J.M., Devogelaer J.P., Lenz M.E., Thonar E.J., and Manicourt D.H. Treatment with calcitonin prevents the net loss of collagen, hyaluronan and proteoglycan aggregates from cartilage in the early stages of canine experimental osteoarthritis. Osteoarthritis Cartilage 12 (2004) 904-911
31. Manicourt D.H., Altman R.D., Williams J.M., Devogelaer J.P., Druetz-Van Egeren A., Lenz M.E., et al. Treatment with calcitonin suppresses the responses of bone, cartilage, and synovium in the early stages of canine experimental osteoarthritis and significantly reduces the severity of the cartilage lesions. Arthritis Rheum 42 (1999) 1159-1167
32. Felson D.T., and Neogi T. Osteoarthritis: is it a disease of cartilage or of bone?. Arthritis Rheum 50 (2004) 341-344