Leptin and the risk of Barrett's oesophagus

Gut

Volumn 57, Issue 4, 2008, Pages 448-454

  Kendall, B J ^a   Macdonald, G A ^b   Hayward, N K ^a   Prins, J B ^b   Brown, I ^c   Walker, N ^d   Pandeya, N ^a   Green, A C ^a   Webb, P M ^a   Whiteman, D C ^a,e  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c SULLIVAN NICOLAIDES PATHOLOGY   (Australia)

^d QML Pathology   (Australia)

^e ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; LEPTIN; BIOLOGICAL MARKER;

ADULT; AGE DISTRIBUTION; AGED; ANAMNESIS; ARTICLE; AUSTRALIA; BARRETT ESOPHAGUS; BODY MASS; CONFIDENCE INTERVAL; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE ASSOCIATION; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OBESITY; PHENOTYPE; PRIORITY JOURNAL; QUESTIONNAIRE; SEX RATIO; VALIDATION PROCESS; ADOLESCENT; BLOOD; CLINICAL TRIAL; GASTROESOPHAGEAL REFLUX; MIDDLE AGED; MULTICENTER STUDY; PILOT STUDY; SEX DIFFERENCE;

ADIPONECTIN; ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; BARRETT ESOPHAGUS; BIOLOGICAL MARKERS; BODY MASS INDEX; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; LEPTIN; MALE; MIDDLE AGED; PILOT PROJECTS; SEX DISTRIBUTION; SEX FACTORS;

EID: 41149088116     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2007.131243     Document Type: Article

References (47)

1. Blot WJ, McLaughlin JK. The changing epidemiology of esophageal cancer. Semin Oncol 1999;26(5 Suppl 15):2-8.
2. Botterweck AA, Schouten LJ, Volovics A, et al. Trends in incidence of adenocarcinoma of the oesophagus and gastric cardia in ten European countries. Int J Epidemiol 2000;29:645-54.
3. Lord RV, Law MG, Ward RL, et al. Rising incidence of oesophageal adenocarcinoma in men in Australia. J Gastroenterol Hepatol 1998;13:356-62.
4. Vizcaino AP, Moreno V, Lambert R, et al. Time trends incidence of both major histologic types of esophageal carcinomas in selected countries, 1973-1995. Int J Cancer 2002;99:860-8.
5. Conio M, Cameron AJ, Romero Y, et al. Secular trends in the epidemiology and outcome of Barrett's oesophagus in Olmsted County, Minnesota. Gut 2001;48:304-9.
6. Kendall BJ, Whiteman DC. Temporal changes in the endoscopic frequency of new cases of Barrett's esophagus in an Australian health region. Am J Gastroenterol 2006;101:1178-82.
7. Post PN, Siersema PD, Van Dekken H. Rising incidence of clinically evident Barrett's oesophagus in the Netherlands: a nation-wide registry of pathology reports. Scand J Gastroenterol 2007;42:17-22.
8. Prach AT, MacDonald TA, Hopwood DA, et al. Increasing incidence of Barrett's oesophagus: education, enthusiasm, or epidemiology? Lancet 1997;350:933.
9. Shaheen NJ. Advances in Barrett's esophagus and esophageal adenocarcinoma. Gastroenterology 2005;128:1554-66.
10. Lagergren J, Bergstrom R, Lindgren A, et al. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. N Engl J Med 1999;340:825-31.
11. Smith KJ, O'Brien SM, Smithers BM, et al. Interactions among smoking, obesity, and symptoms of acid reflux in Barrett's esophagus. Cancer Epidemiol Biomarkers Prev 2005;14:2481-6.
12. Wu AH, Tseng CC, Bernstein L. Hiatal hernia, reflux symptoms, body size, and risk of esophageal and gastric adenocarcinoma. Cancer 2003;98:940-8.
13. Corley DA, Kubo A, Zhao W. Abdominal obesity, ethnicity and gastro-oesophageal reflux symptoms. Gut 2007;56:756-62.
14. Dent J, El-Serag HB, Wallander MA, et al. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005;54:710-17.
15. El-Serag HB, Ergun GA, Pandolfino J, et al. Obesity increases oesophageal acid exposure. Gut 2007;56:749-55.
16. El-Serag HB, Graham DY, Satia JA, et al. Obesity is an independent risk factor for GERD symptoms and erosive esophagitis. Am J Gastroenterol 2005;100:1243-50.
17. Lagergren J. Body measures in relation to gastro-oesophageal reflux. Gut 2007;56:741-2.
18. Chow WH, Blot WJ, Vaughan TL, et al. Body mass index and risk of adenocarcinomas of the esophagus and gastric cardia. J Natl Cancer Inst 1998;90:150-5.
19. Kubo A, Corley DA. Body mass index and adenocarcinomas of the esophagus or gastric cardia: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev 2006;15:872-8.
20. Whiteman DC, Sadeghi S, Pandeya N, et al. Combined effects of obesity, acid reflux and smoking on the risks of adenocarcinoma of the oesophagus. Gut 2008;57:173-80.
21. Corley DA, Kubo A, Levin TR, et al. Abdominal obesity and body mass index as risk factors for Barrett's esophagus. Gastroenterology 2007;133:34-41; quiz 311.
22. Edelstein ZR, Farrow DC, Bronner MP, et al. Central adiposity and risk of Barrett's esophagus. Gastroenterology 2007;133:403-11.
23. Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 2004;4:579-91.
24. Garofalo C, Surmacz E. Leptin and cancer. J Cell Physiol 2006;207:12-22.
25. Considine RV. Regulation of leptin production. Rev Endocr Metab Disord 2001;2:357-63.
26. Hardwick JC, Van Den Brink GR, Offerhaus GJ, et al. Leptin is a growth factor for colonic epithelial cells. Gastroenterology 2001;121:79-90.
27. Ogunwobi O, Mutungi G, Beales IL. Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activation. Endocrinology 2006;147:4505-16.
28. Stattin P, Palmqvist R, Soderberg S, et al. Plasma leptin and colorectal cancer risk: a prospective study in Northern Sweden. Oncol Rep 2003;10:2015-21.
29. Tessitore L, Vizio B, Jenkins O, et al. Leptin expression in colorectal and breast cancer patients. Int J Mol Med 2000;5:421-6.
30. Kelesidis I, Kelesidis T, Mantzoros CS. Adiponectin and cancer: a systematic review. Br J Cancer 2006;94:1221-5.
31. Ogunwobi OO, Beales IL. Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regul Pept 2006;134:105-13.
32. Ishikawa NI, Kitayama J, Kazama S, et al. Plasma adiponectin and gastric cancer. Clin Cancer Res 2005;11:466-72.
33. Sampliner RE. Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus. Am J Gastroenterol 2002;97:1888-95.
34. Westbrook JI, Talley NJ. Empiric clustering of dyspepsia into symptom subgroups: a population-based study. Scand J Gastroenterol 2002;37:917-23.
35. Westbrook JI, Talley NJ, Westbrook MT. Gender differences in the symptoms and physical and mental well-being of dyspeptics: a population based study. Qual Life Res 2002;11:283-91.
36. Chow WH, Finkle WD, McLaughlin JK, et al. The relation of gastroesophageal reflux disease and its treatment to adenocarcinomas of the esophagus and gastric cardia. JAMA 1995;274:474-7.
37. El-Serag HB, Kvapil P, Hacken-Bitar J, et al. Abdominal obesity and the risk of Barrett's esophagus. Am J Gastroenterol 2005;100:2151-6.
38. Stein DJ, El-Serag HB, Kuczynski J, et al. The association of body mass index with Barrett's oesophagus. Aliment Pharmacol Ther 2005;22:1005-10.
39. El-Serag HB, Tran T, Richardson P, et al. Anthropometric correlates of intragastric pressure. Scand J Gastroenterol 2006;41:887-91.
40. Pandolfino JE, El-Serag HB, Zhang Q, et al. Obesity: a challenge to esophagogastric junction integrity. Gastroenterology 2006;130:639-49.
41. Wu JC, Mui LM, Cheung CM, et al. Obesity is associated with increased transient lower esophageal sphincter relaxation. Gastroenterology 2007;132:883-9.
42. Watanabe S, Hojo M, Nagahara A. Metabolic syndrome and gastrointestinal diseases. J Gastroenterol 2007;42:267-74.
43. Liu Z, Uesaka T, Watanabe H, et al. High fat diet enhances colonic cell proliferation and carcinogenesis in rats by elevating serum leptin. Int J Oncol 2001;19:1009-14.
44. Beales IL, Ogunwobi OO. Leptin synergistically enhances the anti-apoptotic and growth-promoting effects of acid in OE33 oesophageal adenocarcinoma cells in culture. Mol Cell Endocrinol 2007;274:60- 8.
45. Beales IL, Ogunwobi O, Cameron E, et al. Activation of Akt is increased in the dysplasia-carcinoma sequence in Barrett's oesophagus and contributes to increased proliferation and inhibition of apoptosis: a histopathological and functional study. BMC Cancer 2007;7:97.
46. Francois F, Roper J, Goodman A, et al. The association of gastric leptin with esophageal inflammation and metaplasia. Gut 2008;57:16-24.
47. Williams LB, Fawcett RL, Waechter AS, et al. Leptin production in adipocytes from morbidly obese subjects: stimulation by dexamethasone, inhibition with troglitazone, and influence of gender. J Clin Endocrinol Metab 2000;85:2678-84.