Comparison of two indirect techniques for local delivery of a high dose of an antimicrobial in the distal portion of forelimbs of horses

American Journal of Veterinary Research

Volumn 69, Issue 3, 2008, Pages 334-342

  Errico, Jason A ^a   Trumble, Troy N ^a,c   Bueno, Aloisio C D ^a   Davis, Jennifer L ^b   Brown, Murray P ^a  

^a University of Florida   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN;

ANIMAL EXPERIMENT; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL ARTHRITIS; BLOOD SAMPLING; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MEGADOSE; DRUG SYNOVIAL FLUID LEVEL; FEMALE; HORSE; INTERMETHOD COMPARISON; INTERPHALANGEAL JOINT; ISOLATED LIMB INFUSION; ISOLATED LIMB RETROGRADE VENOUS INJECTION; MAXIMUM PLASMA CONCENTRATION; METACARPOPHALANGEAL JOINT; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; TOURNIQUET;

AMIKACIN; ANIMALS; ANTI-INFECTIVE AGENTS; CROSS-OVER STUDIES; FEMALE; FORELIMB; HORSES; INFUSIONS, INTRAOSSEOUS; INJECTIONS, INTRAVENOUS; PERFUSION; SYNOVIAL FLUID; TOURNIQUETS;

ANIMALIA; EQUIDAE;

EID: 41049102391     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.69.3.334     Document Type: Article

References (48)

1. Streppa HK, Singer MJ, Budsberg SC. Applications of local antimicrobial delivery systems in veterinary medicine. J Am Vet Med Assoc 2001;219:40-48.
2. Hanssen AD, Osmon DR, Patel R. Local antibiotic delivery systems: where are we and where are we going? Clin Orthop Relat Res 2005;437:111-114.
3. Craig WA. Choosing an antibiotic on the basis of pharmacodynamics. Ear Nose Throat J 1998;77:7-11.
4. Craig WA. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 1998; 26:1-10.
5. Stratton CW. Dead bugs don't mutate: susceptibility issues in the emergence of bacterial resistance. Emerg Infect Dis 2003;9:10-16.
6. Rubio-Martínez LM, Cruz AM. Antimicrobial regional limb perfusion in horses. J Am Vet Med Assoc 2006;228:706-712.
7. Whithair KJ, Bowersock TL, Blevins WE, et al. Regional limb perfusion for antibiotic treatment of experimentally induced septic arthritis. Vet Surg 1992;21:367-373.
8. Santschi EM, Adams SB, Murphy ED. How to perform equine intravenous digital perfusion, in Proceedings. 44th Annu Meet Am Assoc Equine Pract 1998;198-201.
9. Palmer SE, Hogan PM. How to perform regional limb perfusion in the standing horse, in Proceedings. 45th Annu Meet Am Assoc Equine Pract 1999;124-127.
10. Whitehair KJ, Blevins WE, Fessler JF, et al. Regional perfusion of the equine carpus for antibiotic delivery. Vet Surg 1992;21:279-285.
11. Whitehair KJ, Adams SB, Parker JE, et al. Regional limb perfusion with antibiotics in three horses. Vet Surg 1992;21:286-292.
12. Murphey ED, Santschi EM, Papich MG. Regional intravenous perfusion of the distal limb of horses with amikacin sulfate. J Vet Pharmacol Ther 1999;22:68-71.
13. Butt TD, Bailey JV, Dowling PM, et al. Comparison of 2 techniques for regional antibiotic delivery to the equine forelimb: intraosseous perfusion vs. intravenous perfusion. Can Vet J 2001;42:617-622.
14. Mattson S, Boure L, Pearce S, et al. Intraosseous; gentamicin perfusion of the distal metacarpus in standing horse. Vet Surg 2004;33:180-186.
15. Parra-Sanchez A, Lugo J, Boothe DM, et al. Pharmacokinetics and pharmacodynamics of enrofloxacin and a low dose of amikacin administered via regional intravenous limb perfusion in standing horses. Am J Vet Res 2006;67:1687-1695.
16. Navarre CB, Zhang L, Sunkara G, et al. Ceftiofur distribution in plasma and joint fluid following regional limb injection in cattle. J Vet Pharmacol Ther 1999;22:13-19.
17. Gagnon H, Ferguson JG, Papich MG, et al. Single-dose pharmacokinetics of cefazolin in bovine synovial fluid after intravenous regional injection. J Vet Pharmacol Ther 1994;17:31-37.
18. Langer K, Seidler C, Partsch H. Ultrastructural study of the dermal microvasculature in patients undergoing retrograde intravenous pressure infusions. Dermatology 1996;192:103-109.
19. Schaadt J, Crowley R, Miller D, et al. Isolated limb perfusion: a literature review. J Extra Corpor Technol 2002;34:130-143.
20. Ariyan S. Regional isolated perfusion of extremities for melanoma: now a 26-year experience with drugs other than L-phenylalanine mustard. Plast Reconstr Surg 2003;111:1257-1261.
21. Fraser M, Marentay P, Bertha R. A collaborative approach to isolated limb perfusion. Aorn J 1999;70:642-653.
22. Thompson JF, Kam PC, Waugh RC, et al. isolated limb infusion with cytotoxic agents: a simple alternative to isolated limb perfusion. Semin Surg Oncol 1998;14:238-247.
23. Mian R, Henderson MA, Speakman D, et al. Isolated limb infusion for melanoma: a simple alternative to isolated limb perfusion. Can J Surg 2001;44:189-192.
24. Bonenkamp JJ, Thompson JF, de Wilt JH, et al. Isolated limb infusion with fotemustine after dacarbazine chemosensitisation for inoperable loco-regional melanoma recurrence. Eur J Surg Oncol 2004;30:1107-1112.
25. Werner LA, Hardy J, Bertone AL. Bone gentamicin concentration after intra-articular injection or regional intravenous perfusion in the horse. Vet Surg 2003;32:559-565.
26. Scheuch BC, Van Hoogmoed LM, Wilson WD, et al. Comparison of intraosseous or intravenous infusion for delivery of amikacin sulfate to the tibiotarsal joint of horses. Am J Vet Res 2002;63:374-380.
27. Rubio-Martínez LM, López-Sanroman J, Cruz AM, et al. Evaluation of safety and pharmacokinetics of vancomycin after intravenous regional limb perfusion in horses. Am J Vet Res 2005; 66:2107-2113.
28. Adamson PJ, Wilson WD, Hirsh DC, et al. Susceptibility of equine bacterial isolates to antimicrobial agents. Am J Vet Res 1985;46:447-450.
29. Hirsh DC, Jang SS. Antimicrobic susceptibility of bacterial pathogens from horses. Vet Clin North Am Equine Pract 1987;3:181-190.
30. NCCL standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. 4th ed. NCCLS document M7-A4. Wayne, Pa: National Committee for Clinical Laboratory Standards, 1997.
31. Schneider RK. Common bacteria encountered in septic arthritis, in Proceedings. 44th Annu Meet Am Assoc Equine Pract 1998;152-158.
32. Swanson T. Guide for veterinary service and judging of equestrian events. 3rd ed. Golden, Colo: American Association of Equine Practitioners, 1984.
33. Nicolau DP, Quintiliani R, Nightingale CH. Antibiotic kinetics and dynamics for the clinician. Med Clin North Am 1995;79:477-495.
34. Moore RD, Lietman PS, Smith CR. Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration. J Infect Dis 1987;155:93-99.
35. Anderson BH, Firth EC, Whittem T. The disposition of gentamicin in equine plasma, synovial fluid and lymph. J Vet Pharmacol Ther 1995;18:124-131.
36. Rubio-Martínez LM, López-Sanroman J, Cruz AM, et al. Evaluation of safety and pharmacokinetics of vancomycin after intraosseous regional limb perfusion and comparison of results with those obtained after intravenous regional limb perfusion in horses. Am J Vet Res 2006;67:1701-1707.
37. Grice SC, Morell RC, Balestrieri FJ, et al. Intravenous regional anesthesia: evaluation and prevention of leakage under the tourniquet. Anesthesiology 1986;65:316-320.
38. McLaren AC, Rorabeck CH. The pressure distribution under tourniquets. J Bone Joint Surg Am 1985;67A:433-438.
39. Grebing BR, Coughlin MJ. Evaluation of the Esmark bandage as a tourniquet for forefoot surgery. Foot Ankle Int 2004;25:397-405.
40. Abraham E, Amirouche FML. Pressure controlled Esmarch bandage used as a tourniquet. Foot Ankle Int 2000;21:686-689.
41. Mattson SE, Pearce SG, Boure LP, et al. Comparison of intraosseous and intravenous infusion of technetium Tc99m pertechnate in the distal portion of forelimbs in standing horses by use of scintigraphic imaging. Am J Vet Res 2005;66:1267-1272.
42. Kettner NU, Parker JE, Watrous BJ. Intraosseous regional perfusion for treatment of septic physitis in a two-week-old foal. J Am Vet Med Assoc 2003;222:346-350.
43. Rubio-Martínez L, López-Sanroman J, Cruz AM, et al. Medullary plasma pharmacokinetics of vancomycin after intravenous and intraosseous perfusion of the proximal phalanx in horses. Vet Surg 2005;34:618-624.
44. Gilleland LB, Gilleland HE, Gibson JA, et al. Adaptive resistance to aminoglycoside antibiotics in Pseudomonas aeruginosa. J Med Microbiol 1989;29:41-50.
45. Begg EJ, Peddie BA, Chambers ST, et al. Comparison of gentamicin dosing regimens using an in-vitro model. J Antimicrob Chemother 1992;29:427-433.
46. Bryan LE, Van Den Elzen HM. Effects of membrane-energy mutations and cations on streptomycin and gentamicin accumulation by bacteria: a model for entry of streptomycin and gentamicin in susceptible and resistant bacteria. Antimicrob Agents Chemother 1977;12:163-177.
47. McGrath BJ, Lamp KC, Rybak MJ. Pharmacodynamic effects of extended dosing intervals of imipenem alone and in combination with amikacin against Pseudomonas aeruginosa in an in vitro model. Antimicrob Agents Chemother 1993;37:1931-1937.
48. Pille F, De Baere S, Ceelen L, et al. Synovial fluid and plasma concentrations of ceftiofur after regional intravenous perfusion in the horse. Vet Surg 2005;34:610-617.