Evaluation of safety and pharmacokinetics of vancomycin after intravenous regional limb perfusion in horses

American Journal of Veterinary Research

Volumn 66, Issue 12, 2005, Pages 2107-2113

  Rubio Martínez, Luis M ^a,b   López Sanromán, Javier ^a   Cruz, Antonio M ^b   Santos, Martín ^a   San Andrés, Manuel ^a   San Román, Fidel ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; SODIUM CHLORIDE; UREA; VANCOMYCIN;

ANIMAL EXPERIMENT; ANIMAL LAMENESS; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SAFETY; FEMALE; FORELIMB; HORSE; INFECTION; INTERPHALANGEAL JOINT; KIDNEY FUNCTION; LIMB PERFUSION; MALE; METACARPOPHALANGEAL JOINT; NONHUMAN; REGIONAL PERFUSION; SYNOVIAL FLUID LEVEL; UREA BLOOD LEVEL;

ANALYSIS OF VARIANCE; ANIMALS; CREATINE; FORELIMB; GAIT; HORSES; INFUSIONS, INTRAVENOUS; SYNOVIAL FLUID; TIME FACTORS; UREA; VANCOMYCIN;

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 33644799243     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2005.66.2107     Document Type: Article

References (57)

1. Barber M. Methicillin-resistant staphylococci. J Clin Pathol 1961;14:385-393.
2. Panlilio AL, Culver DH, Gaynes RP, et al. Methicillin-resistant Staphylococcus aureus in U.S. hospitals, 1975-1991. Infect Control Hosp Epidemiol 1992;13:582-586.
3. Emori TG, Gaynes RP. An overview of nosocomial infections, including the role of the microbiology laboratory. Clin Microbiol Rev 1993;6:428-442.
4. Devriese LA, Van Damme LR, Fameree L. Methicillin (cloxacillin)-resistant Staphylococcus aureus strains isolated from bovine mastitis cases. Zentralbl Veterinarmed [B] 1972;19:598-605.
5. Tomlin J, Pead MJ, Lloyd DH, et al. Methicillin-resistant Staphylococcus aureus infections in 11 dogs. Vet Rec 1999;144:60-64.
6. Anzai T, Kamada M, Kanemaru T, et al. Isolation of methicillin-resistant Staphylococcus aureus (MRSA) from mares with metritis and its zooepidemiology. J Equine Sci 1996;7:7-11.
7. Seguin JC, Walker RD, Caron JP, et al. Methicillin-resistant Staphylococcus aureus outbreak in a veterinary teaching hospital: potential human-to-animal transmission. J Clin Microbiol 1999;37:1459-1463.
8. Hartmann FA, Trostle SS, Klohnen AA. Isolation of methicillin-resistant Staphylococcus aureus from a postoperative wound infection in a horse. J Am Vet Med Assoc 1997;211:590-592.
9. Trostle SS, Peavey CL, King DS, et al. Treatment of methicillin-resistant Staphylococcus epidermidis infection following repair of an ulnar fracture and humeroradial joint luxation in a horse. J Am Vet Med Assoc 2001;218:554-559.
10. Aldridge KE, Gelfand MS, Schiro DD, et al. The rapid emergence of fluoroquinolone-methicillin-resistant Staphylococcus aureus infections in a community hospital. An in vitro look at alternative antimicrobial agents. Diagn Microbiol Infect Dis 1992;15:601-608.
11. Oguri T. Incidence and antimicrobial susceptibility of clinical isolates of MRSA from 1988 to 1990, from the results of 26 clinical laboratories in Tokyo and the surrounding area [in Japanese]. Nippon Rinsho 1992;50:952-960.
12. Snavely SR, Hodges GR. The neurotoxicity of antibacterial agents. Ann Intern Med 1984;101:92-104.
13. Levine JF. Vancomycin: a review. Med Clin North Am 1987;71:1135-1145.
14. Orsini JA, Ramberg CF Jr, Benson CE, et al. Vancomycin kinetics in plasma and synovial fluid following intravenous administration in horses. J Vet Pharmacol Ther 1992;15:351-363.
15. Fitzgerald RH Jr. Antimicrobial therapy for the musculoskeletal system. Instr Course Lect 1982;31:1-9.
16. Streppa HK, Singer MJ, Budsberg SC. Applications of local antimicrobial delivery systems in veterinary medicine. J Am Vet Med Assoc 2001;219:40-48.
17. Suller MT, Lloyd D. The antibacterial activity of vancomycin towards Staphylococcus aureus under aerobic and anaerobic conditions. J Appl Microbiol 2002;92:866-872.
18. Murphey ED, Santschi EM, Papich MG. Regional intravenous perfusion of the distal limb of horses with amikacin sulfate. J Vet Pharmacol Ther 1999;22:68-71.
19. Navarre CB, Zhang L, Sunkara G, et al. Ceftiofur distribution in plasma and joint fluid following regional limb injection in cattle. J Vet Pharmacol Ther 1999;22:13-19.
20. Butt TD, Bailey JV, Dowling PM, et al. Comparison of 2 techniques for regional antibiotic delivery to the equine forelimb: intraosseous perfusion vs. intravenous perfusion. Can Vet J 2001;42:617-622.
21. Whitehair KJ, Adams SB, Parker JE, et al. Regional limb perfusion with antibiotics in three horses. Vet Surg 1992;21:286-292.
22. Santschi EM, Adams SB, Murphey ED. How to perform equine intravenous digital perfusion, in Proceedings. 44th Annu Conv Am Assoc Equine Pract 1998;44:198-201.
23. Prescott JF. Peptide antibiotics: polymixins, glycopeptides, streptogramins and bacitracin. In: Prescott JF, Baggot JD, Walker RD, eds. Antimicrobial therapy in veterinary medicine. 3rd ed. Ames, Iowa: Iowa University Press, 2000;177-189.
24. Chambers HF. Antimicrobial agents: protein synthesis inhibitors and miscellaneous antibacterial agents. In: Hardman JG, Limbird LE, eds. Goodman & Gilman's the pharmacological basis of therapeutics. 10th ed. New York: McGraw-Hill Book Co, 2001;1240-1272.
25. Farber BF, Moellering RC Jr. Retrospective study of the toxicity of preparations of vancomycin from 1974 to 1981. Antimicrob Agents Chemother 1983;23:138-141.
26. Mellor JA, Kingdom J, Cafferkey M, et al. Vancomycin ototoxicity in patients with normal renal function. Br J Audiol 1984;18:179-180.
27. Pfausler B, Spiss H, Beer R, et al. Treatment of staphylococcal ventriculitis associated with external cerebrospinal fluid drains: a prospective randomized trial of intravenous compared with intraventricular vancomycin therapy. J Neurosurg 2003;98:1040-1044.
28. Baxter GM. Instrumentation and techniques for treating orthopedic infections in horses. Vet Clin North Am Equine Pract 1996;12:303-335.
29. Appel GB, Given DB, Levine LR, et al. Vancomycin and the kidney. Am J Kidney Dis 1986;8:75-80.
30. Nishino Y, Takemura S, Minamiyama Y, et al. Targeting superoxide dismutase to renal proximal tubule cells attenuates vancomycin-induced nephrotoxicity in rats. Free Radic Res 2003;37:373-379.
31. Hodoshima N, Nakano Y, Izumi M, et al. Protective effect of inactive ingredients against nephrotoxicity of vancomycin hydrochloride in rats. Drug Metab Pharmacokinet 2004;19:68-75.
32. Toyoguchi T, Takahashi S, Hosoya J, et al. Nephrotoxicity of vancomycin and drug interaction study with cilastatin in rabbits. Antimicrob Agents Chemother 1997;41:1985-1990.
33. Machado JK, Feferbaum R, Diniz EM, et al. Monitoring the treatment of sepsis with vancomycin in term newborn infants. Rev Hosp Clin Fac Med Sao Paulo 2001;56:17-24.
34. Iwamoto T, Kagawa Y, Kojima M. Clinical efficacy of therapeutic drug monitoring in patients receiving vancomycin. Biol Pharm Bull 2003;26:876-879.
35. de Lalla F, Novelli A, Pellizzer G, et al. Regional and systemic prophylaxis with teicoplanin in monolateral and bilateral total knee replacement procedures: study of pharmacokinetics and tissue penetration. Antimicrob Agents Chemother 1993;37:2693-2698.
36. Robibaro B, Vorbach H, Weigel G, et al. Endothelial cell compatibility of glycopeptide antibiotics for intravenous use. J Antimicrob Chemother 1998;41:297-300.
37. DiPiro JT, Edmiston CE Jr, Bohnen JM. Pharmacodynamics of antimicrobial therapy in surgery. Am J Surg 1996;171:615-622.
38. Laurencin CT, Horan RF, Senatus PB, et al. Stevens-Johnson-type reaction with vancomycin treatment. Ann Pharmacother 1992;26:1520-1521.
39. Vidal C, González Quintela A, Fuente R, et al. Toxic epidermal necrolysis due to vancomycin. Ann Allergy 1992;68:345-347.
40. Stanek C, Fessl L, Awad-Masalmeh M. Penicillin and ampicillin levels in pathologically altered tissue following regional intravenous administration of antibiotics in cattle legs [in German]. Berl Munch Tierarztl Wochenschr 1984;97:162-166.
41. Whitehair KJ, Blevins WE, Fessler JF, et al. Regional perfusion of the equine carpus for antibiotic delivery. Vet Surg 1992;21:279-285.
42. Gagnon H, Ferguson JG, Papich MG, et al. Single-dose pharmacokinetics of cefazolin in bovine synovial fluid after intravenous regional injection. J Vet Pharmacol Ther 1994;17:31-37.
43. Scheuch BC, Van Hoogmoed LM, Wilson WD, et al. Comparison of intraosseous or intravenous infusion for delivery of amikacin sulfate to the tibiotarsal joint of horses. Am J Vet Res 2002;63:374-380.
44. Grice SC, Morell RC, Balestrieri FJ, et al. Intravenous regional anesthesia: evaluation and prevention of leakage under the tourniquet. Anesthesiology 1986;65:316-320.
45. Finsterbush A, Weinberg H. Venous perfusion of the limb with antibiotics for osteomyelitis and other chronic infections. J Bone Joint Surg Am 1972;54:1227-1234.
46. Whitehair KJ, Bowersock TL, Blevins WE, et al. Regional perfusion for antibiotic treatment of experimentally induced septic arthritis. Vet Surg 1992;21:367-373.
47. Mattson SE, Bouré LP, Pearce SG, et al. Intraosseous gentamicin perfusion of the distal metacarpus in standing horses. Vet Surg 2004;33:180-186.
48. Nelson JD. Antibiotic concentrations in septic joint effusions. N Engl J Med 1971;284:349-353.
49. Katzug BG. Basic principles. In: Katzug BG, ed. Basic & clinical pharmacology. 8th ed. New York: McGraw-Hill Book Co, 2001;3-70.
50. Löwdin F, Odenholt I, Cars O. In vitro studies of pharmacodynamic properties of vancomycin against Staphylococcus aureus and Staphylococcus epidermidis. Antimicrob Agents Chemother 1998;42:2739-2744.
51. Zhanel GG. Influence of pharmacokinetic and pharmacodynamic principles on antibiotic selection. Curr Infect Dis Rep 2001;3:29-34.
52. Greenberg RN, Benes CA. Time-kill studies with oxacillin, vancomycin, and teicoplanin versus Staphylococcus aureus. J Infect Dis 1990;161:1036-1037.
53. Knudsen JD, Fuursted K, Raber S, et al. Pharmacodynamics of glycopeptides in the mouse peritonitis model of Streptococcus pneumoniae or Staphylococcus aureus infection. Antimicrob Agents Chemother 2000;44:1247-1254.
54. Lowy FD. Antimicrobial resistance: the example of Staphylococcus aureus. J Clin Invest 2003;111:1265-1273.
55. Burgess DS. Pharmacodynamic principles of antimicrobial therapy in the prevention of resistance. Chest 1999;115(suppl 3):19S-23S.
56. Firth EC, Klein WR, Nouws JF, et al. Effect of induced synovial inflammation on pharmacokinetics and synovial concentration of sodium ampicillin and kanamycin sulfate after systemic administration in ponies. J Vet Pharmacol Ther 1988;11:56-62.
57. AliAbadi FS, Lees P. Antibiotic treatment for animals: effect on bacterial population and dosage regimen optimization. Int J Antimicrob Agents 2000;14:307-313.