Suppression of Bcl-xL expression by a novel tumor-specific RNA interference system inhibits proliferation and enhances radiosensitivity in prostatic carcinoma cells

Cancer Chemotherapy and Pharmacology

Volumn 61, Issue 6, 2008, Pages 943-952

  Wang, Rui ^a   Lin, Fang ^a   Wang, Xi ^a   Gao, Ping ^a   Dong, Ke ^b   Wei, San Hua ^b   Cheng, Shi Yin ^a   Zhang, Hui Zhong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bcl xL; Gene therapy; Inhibitors of apoptosis; PC3; Prostatic carcinoma; Radiosensitivity; RNA interference; Survivin promoter

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; FIREFLY LUCIFERASE; PROTEIN BCL XL; SURVIVIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CARCINOGENICITY; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE OVEREXPRESSION; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MOUSE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CARCINOMA; PROTEIN EXPRESSION; RADIOSENSITIVITY; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

APOPTOSIS; BCL-X PROTEIN; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HUMANS; IN SITU NICK-END LABELING; LUCIFERASES; MALE; NEOPLASM TRANSPLANTATION; PLASMIDS; PROMOTER REGIONS (GENETICS); PROSTATIC NEOPLASMS; RADIATION-SENSITIZING AGENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TETRAZOLIUM SALTS; THIAZOLES; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR STEM CELL ASSAY;

EID: 41049096985     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-007-0548-y     Document Type: Article

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