Suitability of macrophage inflammatory protein-1β production by THP-1 cells in differentiating skin sensitizers from irritant chemicals

Contact Dermatitis

Volumn 58, Issue 4, 2008, Pages 193-198

  Lim, Yeon Mi ^a   Moon, Seong Joon ^b   An, Su Sun ^b   Lee, Soo Jin ^b   Kim, Seo Young ^b   Chang, Ih Seop ^b   Park, Kui Lea ^c   Kim, Hyoung Ah ^d   Heo, Yong ^a  

^a Catholic University of Daegu   (South Korea)

^b AmorePacific Corporation   (South Korea)

^c Korea Food and Drug Administration   (South Korea)

^d The Catholic University of Korea   (South Korea)

Author keywords

Contact dermatitis; MIP 1 ; Skin sensitizing chemicals; THP 1 cell line

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 1 FLUORO 2,4 DINITROBENZENE; 5 CHLORO 2 METHYL 4 ISOTHIAZOLIN 3 ONE; ALDEHYDE DERIVATIVE; BENZALKONIUM CHLORIDE; BENZOCAINE; DICHROMATE POTASSIUM; DIMETHYL SULFOXIDE REDUCTASE; EUGENOL; HEXYL CINNAMIC ALDEHYDE; HYDROQUINONE; IRRITANT AGENT; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NICKEL SULFATE; SALICYLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; SKIN SENSITIZATION;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; ANIMALS; BIOLOGICAL ASSAY; BIOLOGICAL MARKERS; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINE CCL4; ENZYME-LINKED IMMUNOSORBENT ASSAY; GUINEA PIGS; HUMANS; INHIBITORY CONCENTRATION 50; IRRITANTS; MONOCYTES; SKIN; STATISTICS, NONPARAMETRIC; TETRAZOLIUM SALTS; THIAZOLES;

EID: 41049096215     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/j.1600-0536.2007.01311.x     Document Type: Article

References (19)

1. European Union. Council Directive on the approximation of the laws of the Member States relating to cosmetic products (76/768/EEC). Official Journal of the European Union 11.3.2003.
2. OECD. OECD guideline for the testing of chemicals: Test No. 429: skin sensitization; local lymph node assay 04.24.2002.
3. Hirota M, Moro O. MIP-1β, a novel biomarker for in vitro sensitization test using human monocytic cell line. Toxicol In Vitro 2006 : 20 : 736 742.
4. Van Och F M M, Van Loveren H, Van Wolfswinkel J C, Machielsen A J C, Vandebriel R J. Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1α and IL-18 production by a murine and human keratinocytic cell line. Toxicology 2005 : 210 : 95 109.
5. Azam P, Peiffer J L, Chamousset D, Tissier M H, Bonnet P A, Vian L, Fabre I, Ourlin J C. The cytokine-dependent MUTZ-3 cell line as an in vitro model for the screening of contact sensitizers. Toxicol Appl Pharmacol 2006 : 212 : 14 23.
6. Sakaguchi H, Ashikaga T, Miyazawa M et al. Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT) II. An inter-laboratory study of the h-CLAT. Toxicol In Vitro 2006 : 20 : 774 784.
7. Ashikaga T, Yoshida Y, Hirota M et al. Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT) I. Optimization of the h-CLAT protocol. Toxicol In Vitro 2006 : 20 : 767 773.
8. Basketter D A, Gerberick G F, Kimber I, Loveless S E. The local lymph node assay: a viable alternative to currently accepted skin sensitization tests. Food Chem Toxicol 1996 : 34 : 985 997.
9. National Toxicology Program. The murine local lymph node assay: a test method for assessing the allergic contact dermatitis potential of chemicals/compounds. NIH Publication no. 99-4494, 1999.
10. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983 : 65 : 55 63.
11. Basketter D A, Lea L J, Cooper K, Stocks J, Dickens A, Pate I, Dearman R J, Kimber I. Threshold for classification as a skin sensitizer in the local lymph node assay: a statistical evaluation. Food Chem Toxicol 1999 : 37 : 1167 1174.
12. Gerberick G F, Ryan C A, Kimber I, Dearman R J, Lea L J, Basketter D A. Local lymph node assay: validation assessment for regulatory purposes. Am J Contact Dermat 2000 : 11 : 3 18.
13. Wolpe S D, Cerami A. Macrophage inflammatory protein 1 and 2: members of a novel superfamily of cytokines. FASEB J 1989 : 3 : 2565 2573.
14. Tedla N, Wnag H W, McNeil H P, Girolamo N D, Hampartzoumian T, Wakefield D, Lloyd A. Regulation of T lymphocyte trafficking into lymph nodes during an immune response by the chemokines macrophage inflammatory protein (MIP)-1α and MIP-1β. J Immunol 1998 : 161 : 5663 5672.
15. Steiling W, Basketter D, Berthold K et al. Skin sensitisation testing - new perspectives and recommendations. Food Chem Toxicol 2001 : 39 : 293 301.
16. Basketter D A, Scholes E W, Chamberlain M, Barratt M D. An alternative strategy to the use of guinea pig for the identification of skin sensitization hazard. Food Chem Toxicol 1995 : 33 : 1051 1056.
17. Büdinger L, Hertl M. Immunologic mechanisms in hypersensitivity reactions to metal ions: an overview. Allergy 2000 : 55 : 108 115.
18. Miyazawa M, Ito Y, Yoshida Y, Sakaguch H, Suzuki H. Phenotypic alterations and cytokine production in THP-1 cells in response to allergen. Toxicol In Vitro 2007 : 21 : 428 437.
19. Hulette B C, Ryan C A, Gildea L A, Gerberick F. Relationship of CD86 surface marker expression and cytotoxicity on dendrtitic cells exposed to chemical allergen. Toxicol Appl Pharmacol 2005 : 209 : 159 166.