A mechanistic model for the sex-specific response to nalbuphine and naloxone in postoperative pain

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 35, Issue 1, 2008, Pages 69-83

  Kshirsagar, Smita ^a   Gear, Robert ^b   Levine, Jon ^b   Verotta, Davide ^c  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Analgesia; Anti analgesia; NONMEM; Opioids; Pain; Population modeling; Sex

Indexed keywords

NALBUPHINE; NALOXONE;

ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DENTAL SURGERY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOLAR TOOTH; PAIN ASSESSMENT; POSTOPERATIVE PAIN; PRIORITY JOURNAL; SEX DIFFERENCE; VISUAL ANALOG SCALE;

DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MODELS, CHEMICAL; MODELS, STATISTICAL; NALBUPHINE; NALOXONE; PAIN, POSTOPERATIVE; SEX CHARACTERISTICS;

EID: 41049093986     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-007-9076-y     Document Type: Article

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