Treatment Planning and Delivery of External Beam Radiotherapy for Pediatric Sarcoma: The St. Jude Children's Research Hospital Experience

International Journal of Radiation Oncology Biology Physics

Volumn 70, Issue 5, 2008, Pages 1598-1606

  Hua, Chiaho ^a   Gray, Jonathan M ^a   Merchant, Thomas E ^a   Kun, Larry E ^a   Krasin, Matthew J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Pediatric sarcoma; Radiation therapy; Treatment planning

Indexed keywords

DOSIMETRY; DRUG DOSAGE; PATIENT MONITORING; PEDIATRICS;

BRACHYTHERAPY; PEDIATRIC SARCOMA; TREATMENT PLANNING;

RADIOTHERAPY;

ARTICLE; BONE TUMOR; BRACHYTHERAPY; CANCER CONTROL; CHILD; CLINICAL TRIAL; EWING SARCOMA; EXTERNAL BEAM RADIOTHERAPY; FEMALE; HISTOGRAM; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; OSTEOSARCOMA; PRIORITY JOURNAL; RADIATION DOSE; RHABDOMYOSARCOMA; SARCOMA; SOFT TISSUE SARCOMA; SPINAL CORD; TREATMENT PLANNING;

ADOLESCENT; ADULT; BONE NEOPLASMS; BRACHYTHERAPY; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; PROSPECTIVE STUDIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY, CONFORMAL; RADIOTHERAPY, INTENSITY-MODULATED; SARCOMA; SOFT TISSUE NEOPLASMS; TENNESSEE; TUMOR BURDEN;

EID: 40949165756     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.12.013     Document Type: Article

References (34)

1. DeLaney T.F., Trofimov A.V., Engelsman M., and Suit H.D. Advanced-technology radiation therapy in the management of bone and soft-tissue sarcoma. Cancer Control 12 (2005) 27-35
2. Grier H.E., Krailo M.D., Tarbell N.J., et al. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. New Eng J Med 348 (2003) 694-701
3. Donaldson S.S., Meza J., Breneman J.C., et al. Results from the IRS-IV randomized trial of hyperfractionated radiotherapy in children with rhabdomyosarcoma-a report from the IRSG. Int J Radiat Oncol Biol Phys 51 (2001) 718-728
4. Spunt S.L., Poquette C.A., Hurt Y.S., et al. Prognostic factors for children and adolescents with surgically resected nonrhabdomyosarcoma soft tissue sarcoma: an analysis of 121 patients treated at St Jude Children's Research Hospital. J Clin Oncol 17 (1999) 3697-3705
5. Lee N., Akazawa C., Akazawa P., et al. A forward-planned treatment technique using multisegments in the treatment of head-and-neck cancer. Int J Radiat Biol Phys 59 (2004) 584-594
6. Xia P., Pickett B., Vigneault E., et al. Forward or inversely planned segmental multileaf collimator IMRT and sequential tomotherapy to treat multiple dominant intraprostatic lesions of prostate cancer to 90 Gy. Int J Radiat Oncol Biol Phys 51 (2001) 244-254
7. IRB Phase II image-guided radiotherapy protocol, image guided radiotherapy for the treatment of musculoskeletal tumors: A Phase II prospective evaluation of radiation-related treatment effects, St Jude's Children's Research Hospital, principal investigator Matthew J. Krasin, M.D. Activation date: January 9, 2003.
8. Sherouse G.W., and Chaney E.L. The portable virtual simulator. Int J Radiat Biol Phys 21 (1991) 475-482
9. Sailer S.L., Chaney E.L., Rosenman J.G., et al. Treatment planning at the University of North Carolina at Chapel Hill. Sem Radiat Oniol 2 (1992) 267-273
10. Zhu Y., Stovall J., Butler L., et al. Comparison of two immobilization techniques using portal film and digitally reconstructed radiographs for pediatric patients with brain tumors. Int J Radiat Biol Phys 48 (2000) 1233-1240
11. Olch A.J., Followill D., Thomadsen B., et al. In regard to Urie, et al.: current calibration treatment, and treatment planning techniques among institutions participating in the Children's Oncology Group. IJROBP 2003;55:245-260. Int J Radiat Biol Phys 56 (2003) 1209-1210
12. Wang J.Z., Li X.A., D'Souza W.D., et al. Impact of prolonged fraction delivery times on tumor control: A note of caution for intensity-modulated radiation therapy (IMRT). Int J Radiat Biol Phys 57 (2003) 543-552
13. Fowler J.F., Welsh J.S., and Howard S.P. Loss of biological effect in prolonged fraction delivery. Int J Radiat Biol Phys 53 (2002) 1350-1360
14. Paganetti H. Change in tumor cell response due to prolonged dose delivery times in fractioned radiation therapy. Int J Radiat Biol Phys 63 (2005) 892-900
15. Merchant T.E., Morris E.B., Kun L.E., et al. A prospective study of spinal cord dosimetry and neurologic outcome for infratentorial ependymoma. Int J Radiat Biol Phys 66 (2006) S111
16. Merchant T.E., Gould C.J., Xiong X., et al. Early neuron-otologic effects of three-dimensional irradiation in children with primary brain tumors. Int J Radiat Biol Phys 58 (2004) 1194-1207
17. Hua C., Bass J., Khan R.B., et al. Hearing loss after radiotherapy alone for pediatric brain tumors: The effect of cochlea dose. Int J Radiat Biol Phys 66 (2006) S112
18. Marcus K.J., Goumnerova L., Billett A.L., et al. Stereotactic radiotherapy for localized low-grade gliomas in children: Final results of a prospective trial. Int J Radiat Biol Phys 61 (2005) 374-379
19. Merchent T.E., Zhu Y., Thompson, et al. Preliminary results from a Phase II trial of a conformal radiation therapy for pediatric patients with localized low-grade astrocytoma and ependymoma. Int J Radiat Biol Phys 52 (2002) 325-332
20. Pediatric Brain Tumor Consortium Protocol PBTC-14, Phase I/II trial of R115777 and XRT in pediatric patients with newly diagnosed non-disseminated intrinsic diffuse brainstem gliomas, study chair Daphne Haas-Kogan, M.D. Version date: July 27, 2006.
21. Children's Oncology Group Protocol ARST0431, Intensive multi-agent therapy, including dose-compressed cycles of Ifosfamide/Etoposide (IE) and Vincristine/Doxorubicin/Cyclophosphamide (VDC) for patients with high-risk rhabdomyosarcoma, study chair Brenda Weigel, M.D. Version date: August 3, 2006.
22. Krasin M.J., Xiong X., Wu S., and Merchant T.E. The effects of external beam irradiation on the growth of flat bones in children: modeling a dose-volume effect. Int J Radiat Biol Phys 62 (2005) 1458-1463
23. Merchant T.E., Nguyen L., Nguyen D., et al. Differential attenuation of clavicle growth after asymmetric mantle radiotherapy. Int J Radiat Biol Phys 59 (2004) 556-561
24. Paulino A.C., Wen B.C., Brown C.K., et al. Late effects in children treated with radiation therapy for Wilms' tumor. Int J Radiat Biol Phys 46 (2000) 1239-1246
25. Riseborough E.J., Grabias S.L., Burton R.I., et al. Skeletal alterations following irradiation for Wilms' tumor. J Bone Joint Surg 58 (1976) 526-536
26. Paulussen M., Ahrens S., Craft A.W., et al. Ewing's tumors with primary lung metastases: survival analysis of 114 (European Intergroup) Cooperative Ewing Sarcoma Studies patients. J Clin Oncol 58 (1998) 3044-3052
27. Whelan J.S., Burcombe R.J., Janinis J., et al. A systematic review of the role of pulmonary irradiation in the management of primary bone tumours. Ann Oncol 13 (2002) 23-30
28. Bradley J., Graham M.V., Winter K., et al. Toxicity and outcome results of RTOG 9311: A phase I-II dose escalation study using three-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma. Int J Radiat Biol Phys 61 (2005) 318-328
29. Cassady J.R. Clinical radiation nephropathy. Int J Radiat Biol Phys 31 (1995) 1249-1256
30. Carrie C., Hoffstetter S., Gomez F., et al. Impact of targeting deviations on outcome in medulloblastoma: Study of the French Society of Pediatric Oncology (SFOP). Int J Radiat Biol Phys 57 (1999) 435-439
31. Taylor R.E., Bailey C.C., Robinson K.J., et al. Impact of radiotherapy parameters on outcome in the International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 study of preradiotherapy chemotherapy for M0-M1 medulloblastoma. Int J Radiat Biol Phys 58 (2004) 1184-1193
32. Miralbell R., Fitzgerald T.J., Laurie F., et al. Radiotherapy in pediatric medulloblastoma: quality assessment of pediatric oncology group trial 9031. Int J Radiat Biol Phys 64 (2006) 1325-1330
33. Krasin M.J., Merchant T.E., Spunt S.L., et al. Early results of a prospective study delivering limited margin radiotherapy for pediatric non-rhabdo-soft tissue sarcomas (NRSTS) and aggressive fibromatoses (AF). Int J Radiat Biol Phys 66 (2006) S112
34. Hua C., Merchant T.E., Spunt S.L., and Krasin M.J. Early results of a prospective study delivering limited margin radiotherapy for pediatric patients with rhabdomyosarcoma. Int J Radiat Biol Phys 69 (2007) S37