Results from the IRS-IV randomized trial of hyperfractionated radiotherapy in children with rhabdomyosarcoma - A report from the IRSG

International Journal of Radiation Oncology Biology Physics

Volumn 51, Issue 3, 2001, Pages 718-728

  Donaldson, Sarah S ^a   Meza, Jane ^b   Breneman, John C ^c   Crist, William M ^d   Laurie, Fran ^e   Qualman, Stephen J ^f   Wharam, Moody ^g  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

^e Quality Assurance Review Center   (United States)

^f NATIONWIDE CHILDREN S HOSPITAL   (United States)

^g JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Adolescence; Childhood; Hyperfractionation; IRS IV; Radiotherapy; Rhabdomyosarcoma; Sarcoma

Indexed keywords

CHEMOTHERAPY; DIAGNOSIS; HISTOLOGY; PATHOLOGY; PATIENT TREATMENT; SURGERY; TOXICITY;

SKIN REACTIONS;

RADIOTHERAPY;

ANTIINFECTIVE AGENT; CYCLOPHOSPHAMIDE; DACTINOMYCIN; ETOPOSIDE; IFOSFAMIDE; VINCRISTINE;

ADOLESCENT; ADULT; AGE; ARTICLE; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER STAGING; CARCINOMA IN SITU; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLOW UP; HEAD CANCER; HIGH RISK POPULATION; HUMAN; INFANT; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MENINGIOMA; NECK CANCER; PATIENT COMPLIANCE; PRIORITY JOURNAL; PROGNOSIS; RADIATION INJURY; RANDOMIZED CONTROLLED TRIAL; RHABDOMYOSARCOMA; SURVIVAL RATE; TREATMENT FAILURE; TREATMENT OUTCOME; TUMOR VOLUME;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; CHILD; CHILD, PRESCHOOL; DOSE FRACTIONATION; FEMALE; HUMANS; INFANT; MALE; PATIENT COMPLIANCE; RADIATION INJURIES; REMISSION INDUCTION; RHABDOMYOSARCOMA; TREATMENT OUTCOME;

EID: 0035501515     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(01)01709-6     Document Type: Article

References (39)

1. Local and regional control by radiation of rhabdomyosarcoma in IRS II
2. Analysis of patterns of failure, group III RT patients treated on IRS-III
3. Rhabdomyosarcoma of the head and neck in children: Combination treatment by irradiation and chemotherapy
4. Late effects of therapy in orbital rhabdomyosarcoma in children: A report from the Intergroup Rhabdomyosarcoma Study
5. Acute and late effects on normal tissues following chemo-radiotherapy for childhood rhabdomyosarcoma and Ewing's sarcoma
6. The linear-quadratic formula and progress in fractionated radiotherapy
7. Hyperfractionation vs. conventional fractionation in oropharyngeal carcinoma: Final analysis of a randomized trial of the EORTC Cooperative Group of Radiotherapy
8. Status of the experience of the EORTC cooperative group of radiotherapy with hyperfractionated and accelerated radiotherapy regimens
9. Improved local control for advanced oropharyngeal carcinoma following twice daily radiation therapy
10. Twice-a-day radiation therapy for supraglottic carcinoma
11. Preliminary results of alternating combination chemotherapy (CT) and hyperfractionated radiotherapy (HART) in advanced rhabdomyosarcoma (RMS)
12. Hyperfractionated radiation in children with rhabdomyosarcoma: Results of an Intergroup Rhabdomyosarcoma Pilot Study
13. Classification of rhabdomyosarcomas and related sarcomas, pathologic aspects and proposal for a new classification - An Intergroup Rhabdomyosarcoma Study
14. Prognostic significance of staging factors of the UICC staging system in childhood rhabdomyosarcoma: A report from the Intergroup Rhabdomyosarcoma Study (IRS-II)
15. Intergroup Rhabdomyosarcoma Study-IV: Results for patients with non-metastatic disease
16. Nonparametric estimation from incomplete observations
17. Sample size requirements for evaluating a conservative therapy
18. Regression models and life-tables
19. Indications for radiotherapy and chemotherapy after complete resection in rhabdomyosarcoma: A report from the Intergroup Rhabdomyosarcoma Studies I to III
20. Radiation therapy combined with systemic chemotherapy of rhabdomyosarcoma in children: Local control in patients enrolled in the Intergroup Rhabdomyosarcoma Study
21. The Intergroup Rhabdomyosarcoma Study-II
22. Radiation therapy for rhabdomyosarcoma: Local failure risk for clinical group III patients in Intergroup Rhabdomyosarcoma Study II
23. Pediatric orofacial and laryngopharyngeal rhabdomyosarcoma: An Intergroup Rhabdomyosarcoma Study report
24. Parameningeal rhabdomyosarcoma in the young
25. Local control of embryonal rhabdomyosarcoma in children by radiation therapy when combined with concomitant chemotherapy
26. Dental abnormalities in long term survivors of head and neck rhabdomyosarcoma
27. Radiation fractionation sensitivity of epiphysial cartilage in a weanling rat model
28. Radiotherapy of the rhabdomyosarcoma R1H of the rat: Kinetics of cellular inactivation by fractionated irradiation
29. Radiotherapy of the rhabdomyosarcoma R1H of the rat: The influence of the number of fractions on tumor and skin response
30. Twice-a-day irradiation technique for squamous cell carcinoma of the head and neck
31. Twice-a-day irradiation of squamous cell carcinoma of the head and neck
32. Hyperfractionation for head and neck cancer
33. Hyperfractionated radiotherapy in brain stem tumors: Results of a Pediatric Oncology Group Study
34. Hyperfractionated radiation therapy in brainstem tumors: Results of treatment at the 7020 cGy dose level of Pediatric Oncology Group Study 8495
35. Hyperfractionated radiation therapy (72 Gy) for children with brain stem gliomas: A Children's Cancer Group Phase I/II Trial
36. Results of a pilot study of hyperfractionted radiation therapy for children with brainstem gliomas
37. Improvement of local tumor control in primary nonresectable rhabdomyosarcoma (RMS) in children by early, preoperative, hyperfractionated radiotherapy (RT) given simultaneous to chemotherapy (CT): Report of the German Cooperative Soft Tissue Sarcoma Studies CWS-81 and 86
38. Infants younger than 1 year of age with rhabdomyosarcoma