In vitro- and in vivo-induced transgene expression in human embryonic stem cells and derivatives

Stem Cells

Volumn 26, Issue 2, 2008, Pages 525-533

  Xia, Xiaofeng ^a   Ayala, Melvin ^b   Thiede, Benjamin R ^b   Zhang, Su Chun ^a,b,c  

^a WiCell Research Institute   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Gene delivery systems in vivo or in vitro; Gene modification; Human embryonic stem cell; Inducible gene expression

Indexed keywords

DOXYCYCLINE; GREEN FLUORESCENT PROTEIN;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE EXPRESSION; GERM LAYER; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; STEM CELL TRANSPLANTATION; TRANSGENE;

ADMINISTRATION, ORAL; ANIMALS; BRAIN TISSUE TRANSPLANTATION; CELL DIFFERENTIATION; CELL LINE; DOXYCYCLINE; EMBRYONIC STEM CELLS; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HUMANS; INSULIN; MICE; MICE, SCID; MYOCYTES, CARDIAC; NEURONS; RECOMBINANT PROTEINS; TERATOMA; TETRACYCLINE; TRANSFECTION;

ANIMALIA;

EID: 40949165288     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0710     Document Type: Article

References (32)

1. Thomson JA, Itskovitz-Eldor J, Shapiro SS et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282:1145-1147.
2. Reubinoff BE, Pera MF, Fong CY et al. Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro. Nat Biotechnol 2000;18:399-404.
3. Zwaka TP, Thomson JA. Homologous recombination in human embryonic stem cells. Nat Biotechnol 2003;21:319-321.
4. Urbach A, Schuldiner M, Benvenisty N. Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells. STEM CELLS 2004;22:635-641.
5. Nolden L, Edenhofer F, Haupt S et al. Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase. Nat Methods 2006;3:461-467.
6. Vallier L, Alexander M, Pedersen R. Conditional gene expression in human embryonic stem cells. STEM CELLS 2007;25:1490-1497.
7. Vieyra DS, Goodell MA. Pluripotentiality and conditional transgene regulation in human embryonic stem cells expressing insulated tetracycline-ON transactivator. STEM CELLS 2007;25:2559-2566.
8. Zhou BY, Ye Z, Chen G et al. Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. STEM CELLS 2007;25:779-789.
9. Eiges R, Schuldiner M, Drukker M et al. Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells. Curr Biol 2001;11:514-518.
10. Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000;24:372-376.
11. Gossen M, Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci U S A 1992;89:5547-5551.
12. Gossen M, Freundlieb S, Bender G et al. Transcriptional activation by tetracyclines in mammalian cells. Science 1995;268:1766-1769.
13. Shin MK, Levorse JM, Ingram RS et al. The temporal requirement for endothelin receptor-B signalling during neural crest development. Nature 1999;402:496-501.
14. Jaisser F. Inducible gene expression and gene modification in transgenic mice. J Am Soc Nephrol 2000;11(suppl 16):S95-S100.
15. Kobayashi K, Yasuhara T, Agari T et al. Control of dopamine-secretion by Tet-Off system in an in vivo model of parkinsonian rat. Brain Res 2006;1102:1-11.
16. Costa M, Dottori M, Ng E et al. The hESC line Envy expresses high levels of GFP in all differentiated progeny. Nat Methods 2005;2:259-260.
17. Costa M, Dottori M, Sourris K et al. A method for genetic modification of human embryonic stem cells using electroporation. Nat Protoc 2007;2:792-796.
18. Zhang SC, Wernig M, Duncan ID et al. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol 2001;19:1129-1133.
19. Pankratz MT, Li XJ, Lavaute TM et al. Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage. STEM CELLS 2007;25:1511-1520.
20. Kehat I, Kenyagin-Karsenti D, Snir M et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 2001;108:407-414.
21. D'Amour KA, Agulnick AD, Eliazer S et al. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol 2005;23:1534-1541.
22. D'Amour KA, Bang AG, Eliazer S et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006;24:1392-1401.
23. Guillaume DJ, Johnson MA, Li XJ et al. Human embryonic stem cell-derived neural precursors develop into neurons and integrate into the host brain. J Neurosci Res 2006;84:1165-1176.
24. Okabe M, Ikawa M, Kominami K et al. 'Green mice' as a source of ubiquitous green cells. FEBS Lett 1997;407:313-319.
25. Muotri AR, Nakashima K, Toni N et al. Development of functional human embryonic stem cell-derived neurons in mouse brain. Proc Natl Acad Sci U S A 2005;102:18644-18648.
26. Buzzard JJ, Gough NM, Crook JM et al. Karyotype of human ES cells during extended culture. Nat Biotechnol 2004;22:381-382; author reply 382.
27. Draper JS, Smith K, Gokhale P et al. Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat Biotechnol 2004;22:53-54.
28. Kyba M, Perlingeiro RC, Daley GQ. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell 2002;109:29-37.
29. Masui S, Shimosato D, Toyooka Y et al. An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit. Nucleic Acids Res 2005;33:e43.
30. Zambrowicz BP, Imamoto A, Fiering S et al. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A 1997;94:3789-3794.
31. Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999;21:70-71.
32. Corish P, Tyler-Smith C. Attenuation of green fluorescent protein halflife in mammalian cells. Protein Eng 1999;12:1035-1040.