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Volumn 39, Issue 4, 2007, Pages 305-307

Why thrombin PAR1 receptors are important to the cardiac surgical patient

Author keywords

Antagonist; Cardiac surgery; Receptor; Thrombin

Indexed keywords

APROTININ; PLASMIN; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 1 ANTAGONIST; THROMBIN; THROMBIN RECEPTOR; UNCLASSIFIED DRUG; ANTIFIBRINOLYTIC AGENT; LIPOPROTEIN; LIPOPROTEIN-ASSOCIATED COAGULATION INHIBITOR; PROTEINASE ACTIVATED RECEPTOR; TISSUE FACTOR PATHWAY INHIBITOR;

EID: 40949152481     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (6)

References (20)
  • 1
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu T-KH, Hung DT, Wheaton VI, Coughlin SR. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 1991;64:1057-68.
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.-K.H.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 3
    • 0029849778 scopus 로고    scopus 로고
    • Cleavage of the thrombin receptor: Identification of potential activators and inactivators
    • Parry MA, Myles T, Tschopp J, Stone SR. Cleavage of the thrombin receptor: identification of potential activators and inactivators. Biochem J. 1996;320:335-41.
    • (1996) Biochem J , vol.320 , pp. 335-341
    • Parry, M.A.1    Myles, T.2    Tschopp, J.3    Stone, S.R.4
  • 4
    • 33846541231 scopus 로고    scopus 로고
    • Protease activated receptors: Clinical relevance to hemostasis and inflammation
    • Landis RC. Protease activated receptors: clinical relevance to hemostasis and inflammation. Hematol Oncol Clin North Am. 2007;21:103-13.
    • (2007) Hematol Oncol Clin North Am , vol.21 , pp. 103-113
    • Landis, R.C.1
  • 5
    • 33845955449 scopus 로고    scopus 로고
    • Proteinase-activated receptors, targets for kallikrein signaling
    • Oikonomopoulou K, Hansen KK, Saifeddine M, et al. Proteinase-activated receptors, targets for kallikrein signaling. J Biol Chem. 2006;281:32095-112.
    • (2006) J Biol Chem , vol.281 , pp. 32095-32112
    • Oikonomopoulou, K.1    Hansen, K.K.2    Saifeddine, M.3
  • 8
    • 13044257730 scopus 로고    scopus 로고
    • Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor
    • Andrade-Gordon P, Maryanoff BE, Derian CK, et al. Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor. Proc Natl Acad Sci USA. 1999;96:12257-62.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12257-12262
    • Andrade-Gordon, P.1    Maryanoff, B.E.2    Derian, C.K.3
  • 9
    • 0023204701 scopus 로고
    • Effect of aprotinin on need for blood transfusion after repeat open-heart surgery
    • Royston D, Bidstrup BP, Taylor KM, Sapsford RN. Effect of aprotinin on need for blood transfusion after repeat open-heart surgery. Lancet. 1987;2:1289-91.
    • (1987) Lancet , vol.2 , pp. 1289-1291
    • Royston, D.1    Bidstrup, B.P.2    Taylor, K.M.3    Sapsford, R.N.4
  • 10
    • 0023608558 scopus 로고
    • Effects of aprotinin on hemostatic mechanisms during cardiopulmonary bypass
    • van Oeveren W, Jansen NJ, Bidstrup BP, et al. Effects of aprotinin on hemostatic mechanisms during cardiopulmonary bypass. Ann Thorac Surg. 1987;44:640-5.
    • (1987) Ann Thorac Surg , vol.44 , pp. 640-645
    • van Oeveren, W.1    Jansen, N.J.2    Bidstrup, B.P.3
  • 11
    • 0026493593 scopus 로고
    • Aprotinin prevents cardiopulmonary bypass-induced platelet dysfunction. A scanning electron microscope study
    • Mohr R, Goor DA, Lusky A, Lavee J. Aprotinin prevents cardiopulmonary bypass-induced platelet dysfunction. A scanning electron microscope study. Circulation. 1992;86:II405-9.
    • (1992) Circulation , vol.86
    • Mohr, R.1    Goor, D.A.2    Lusky, A.3    Lavee, J.4
  • 12
    • 0032005521 scopus 로고    scopus 로고
    • The platelet thrombin receptor and postoperative bleeding
    • Ferraris VA, Ferraris SP, Singh A, et al. The platelet thrombin receptor and postoperative bleeding. Ann Thorac Surg. 1998;65:352-8.
    • (1998) Ann Thorac Surg , vol.65 , pp. 352-358
    • Ferraris, V.A.1    Ferraris, S.P.2    Singh, A.3
  • 13
    • 0031793958 scopus 로고    scopus 로고
    • Analyses of coronary graft patency after aprotinin use: Results from the International Multicenter Aprotinin Graft Patency Experience (IMAGE) trial
    • Alderman EL, Levy JH, Rich JB, et al. Analyses of coronary graft patency after aprotinin use: Results from the International Multicenter Aprotinin Graft Patency Experience (IMAGE) trial. J Thorac Cardiovasc Surg. 1998;116:716-30.
    • (1998) J Thorac Cardiovasc Surg , vol.116 , pp. 716-730
    • Alderman, E.L.1    Levy, J.H.2    Rich, J.B.3
  • 15
    • 7544236615 scopus 로고    scopus 로고
    • Clinical inhibition of the seven-transmembrane thrombin receptor (PAR1) by intravenous aprotinin during cardiothoracic surgery
    • Day JR, Punjabi PP, Randi AM, Haskard DO, Landis RC, Taylor KM. Clinical inhibition of the seven-transmembrane thrombin receptor (PAR1) by intravenous aprotinin during cardiothoracic surgery. Circulation. 2004;110:2597-600.
    • (2004) Circulation , vol.110 , pp. 2597-2600
    • Day, J.R.1    Punjabi, P.P.2    Randi, A.M.3    Haskard, D.O.4    Landis, R.C.5    Taylor, K.M.6
  • 17
    • 29144450966 scopus 로고    scopus 로고
    • Aprotinin shows both hemostatic and antithrombotic effects during off-pump coronary artery bypass grafting
    • Poston RS, White C, Gu J, et al. Aprotinin shows both hemostatic and antithrombotic effects during off-pump coronary artery bypass grafting. Ann Thorac Surg. 2006;81:104-10.
    • (2006) Ann Thorac Surg , vol.81 , pp. 104-110
    • Poston, R.S.1    White, C.2    Gu, J.3
  • 18
    • 4444380033 scopus 로고    scopus 로고
    • Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: A systematic review and meta-analysis of randomized clinical trials
    • Sedrakyan A, Treasure T, Elefteriades JA. Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: A systematic review and meta-analysis of randomized clinical trials. J Thorac Cardiovasc Surg. 2004;128:442-8.
    • (2004) J Thorac Cardiovasc Surg , vol.128 , pp. 442-448
    • Sedrakyan, A.1    Treasure, T.2    Elefteriades, J.A.3
  • 19
    • 1242306912 scopus 로고    scopus 로고
    • Platelets in patients with acute ischemic stroke are exhausted and refractory to thrombin, due to cleavage of the seven-transmembrane thrombin receptor (PAR-1)
    • Jurk K, Jahn UR, Van AH, et al. Platelets in patients with acute ischemic stroke are exhausted and refractory to thrombin, due to cleavage of the seven-transmembrane thrombin receptor (PAR-1). Thromb Haemost. 2004;91:334-44.
    • (2004) Thromb Haemost , vol.91 , pp. 334-344
    • Jurk, K.1    Jahn, U.R.2    Van, A.H.3
  • 20
    • 30044439555 scopus 로고    scopus 로고
    • Aprotinin inhibits proinflammatory activation of endothelial cells by thrombin through the protease-activated receptor 1
    • Day JRS, Taylor KM, Lidington EA, et al. Aprotinin inhibits proinflammatory activation of endothelial cells by thrombin through the protease-activated receptor 1. J Thorac Cardiovasc Surg. 2006;131:21-7.
    • (2006) J Thorac Cardiovasc Surg , vol.131 , pp. 21-27
    • Day, J.R.S.1    Taylor, K.M.2    Lidington, E.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.