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Volumn 131, Issue 1, 2006, Pages 21-27

Aprotinin inhibits proinflammatory activation of endothelial cells by thrombin through the protease-activated receptor 1

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; APROTININ; INTERLEUKIN 6; KALLIKREIN; PROTEIN P42; PROTEIN P44; PROTEINASE ACTIVATED RECEPTOR 1; SPAN 12 ANTIBODY; THROMBIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 30044439555     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2005.08.050     Document Type: Article
Times cited : (36)

References (37)
  • 1
    • 0027327680 scopus 로고
    • Thrombin production, inactivation and expression during open heart surgery measured by assays for activation fragments including new ELISA for prothrombin fragment F1 + 2
    • M.D. Boisclar, D.A. Lane, H. Philippou, S. Sheikh, B. Hunt Thrombin production, inactivation and expression during open heart surgery measured by assays for activation fragments including new ELISA for prothrombin fragment F1 + 2 Thromb Haemost 70 1993 253 258
    • (1993) Thromb Haemost , vol.70 , pp. 253-258
    • Boisclar, M.D.1    Lane, D.A.2    Philippou, H.3    Sheikh, S.4    Hunt, B.5
  • 2
    • 0027249775 scopus 로고
    • Thrombin generation during cardiac surgery: Is heparin the ideal anticoagulant?
    • S.J. Brister, F.A. Ofosu, M.R. Buchanan Thrombin generation during cardiac surgery is heparin the ideal anticoagulant? Thromb Haemost 70 1993 259 262
    • (1993) Thromb Haemost , vol.70 , pp. 259-262
    • Brister, S.J.1    Ofosu, F.A.2    Buchanan, M.R.3
  • 3
    • 0030297174 scopus 로고    scopus 로고
    • Endothelial cell injury in cardiovascular surgery: The procoagulant response
    • E.M. Boyle, E.D. Verrier, B.D. Spiess Endothelial cell injury in cardiovascular surgery the procoagulant response Ann Thorac Surg 62 1996 1549 1557
    • (1996) Ann Thorac Surg , vol.62 , pp. 1549-1557
    • Boyle, E.M.1    Verrier, E.D.2    Spiess, B.D.3
  • 4
    • 0032005521 scopus 로고    scopus 로고
    • The platelet thrombin receptor and postoperative bleeding
    • V.A. Ferraris, S.P. Ferraris, A. Singh The platelet thrombin receptor and postoperative bleeding Ann Thorac Surg 65 1998 352 358
    • (1998) Ann Thorac Surg , vol.65 , pp. 352-358
    • Ferraris, V.A.1    Ferraris, S.P.2    Singh, A.3
  • 5
    • 4544359022 scopus 로고    scopus 로고
    • PAR1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia
    • E.E. Olsen, P. Lyuboslavsky, S.F. Traynelis, R.J. McKeon PAR1 deficiency protects against neuronal damage and neurologic deficits after unilateral cerebral hypoxia/ischemia J Cereb Blood Flow Metab 24 2004 964 971
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 964-971
    • Olsen, E.E.1    Lyuboslavsky, P.2    Traynelis, S.F.3    McKeon, R.J.4
  • 6
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • T.K. Vu, D.T. Hung, V.I. Wheaton, S.R. Coughlin Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation Cell 64 1991 1057 1068
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 7
    • 0026775223 scopus 로고
    • Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides
    • R.R. Vassallo Jr, T. Kieber-Emmons, K. Cichowski, L.F. Brass Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides J Biol Chem 267 1992 6081 6085
    • (1992) J Biol Chem , vol.267 , pp. 6081-6085
    • Vassallo Jr., R.R.1    Kieber-Emmons, T.2    Cichowski, K.3    Brass, L.F.4
  • 8
    • 0030947907 scopus 로고    scopus 로고
    • Endothelial cell thrombin receptors and PAR-2. Two protease-activated receptors located in a single cellular environment
    • M. Molino, M.J. Woolkalis, J. Reavey-Cantwell Endothelial cell thrombin receptors and PAR-2. Two protease-activated receptors located in a single cellular environment J Biol Chem 272 1997 11133 11141
    • (1997) J Biol Chem , vol.272 , pp. 11133-11141
    • Molino, M.1    Woolkalis, M.J.2    Reavey-Cantwell, J.3
  • 9
    • 0030036714 scopus 로고    scopus 로고
    • Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes
    • R. Kranzhofer, S.K. Clinton, K. Ishii, S.R. Coughlin, J.W. Fenton 2nd, P. Libby Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes Circ Res 79 1996 286 294
    • (1996) Circ Res , vol.79 , pp. 286-294
    • Kranzhofer, R.1    Clinton, S.K.2    Ishii, K.3    Coughlin, S.R.4    Fenton II, J.W.5    Libby, P.6
  • 10
    • 0033559805 scopus 로고    scopus 로고
    • Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
    • M.L. Kahn, M.M. Nakanishi, M.J. Shapiro, H. Ishihara, S.R. Coughlin Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin J Clin Invest 103 1999 879 887
    • (1999) J Clin Invest , vol.103 , pp. 879-887
    • Kahn, M.L.1    Nakanishi, M.M.2    Shapiro, M.J.3    Ishihara, H.4    Coughlin, S.R.5
  • 11
    • 0242363128 scopus 로고    scopus 로고
    • The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia
    • C.E. Junge, T. Sugawara, G. Mannaioni The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia Proc Natl Acad Sci U S A 100 2003 13019 13024
    • (2003) Proc Natl Acad Sci U S a , vol.100 , pp. 13019-13024
    • Junge, C.E.1    Sugawara, T.2    Mannaioni, G.3
  • 12
    • 0032529677 scopus 로고    scopus 로고
    • Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106)
    • G. Kaplanski, V. Marin, M. Fabrigoule Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106) Blood 92 1998 1259 1267
    • (1998) Blood , vol.92 , pp. 1259-1267
    • Kaplanski, G.1    Marin, V.2    Fabrigoule, M.3
  • 13
    • 0034667689 scopus 로고    scopus 로고
    • Induction of decay-accelerating factor by thrombin through a protease-activated receptor 1 and protein kinase C-dependent pathway protects vascular endothelial cells from complement-mediated injury
    • E.A. Lidington, D.O. Haskard, J.C. Mason Induction of decay-accelerating factor by thrombin through a protease-activated receptor 1 and protein kinase C-dependent pathway protects vascular endothelial cells from complement-mediated injury Blood 96 2000 2784 2792
    • (2000) Blood , vol.96 , pp. 2784-2792
    • Lidington, E.A.1    Haskard, D.O.2    Mason, J.C.3
  • 14
    • 0037114701 scopus 로고    scopus 로고
    • The proximal serum response element in the Egr-1 promoter mediates response to thrombin in primary human endothelial cells
    • S.Q. Wu, T. Minami, D.J. Donovan, W.C. Aird The proximal serum response element in the Egr-1 promoter mediates response to thrombin in primary human endothelial cells Blood 100 2002 4454 4461
    • (2002) Blood , vol.100 , pp. 4454-4461
    • Wu, S.Q.1    Minami, T.2    Donovan, D.J.3    Aird, W.C.4
  • 15
    • 0034967927 scopus 로고    scopus 로고
    • Administration of a potent antagonist of protease-activated receptor-1 (PAR1) attenuates vascular restenosis following balloon angioplasty in rats
    • P. Andrade-Gordon, C.K. Derian, B.E. Maryanoff Administration of a potent antagonist of protease-activated receptor-1 (PAR1) attenuates vascular restenosis following balloon angioplasty in rats J Pharmacol Exp Ther 298 2001 34 42
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 34-42
    • Andrade-Gordon, P.1    Derian, C.K.2    Maryanoff, B.E.3
  • 16
    • 0036797590 scopus 로고    scopus 로고
    • Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
    • L. Covic, M. Misra, J. Badar, C. Singh, A. Kuliopulos Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation Nat Med 8 2002 1161 1165
    • (2002) Nat Med , vol.8 , pp. 1161-1165
    • Covic, L.1    Misra, M.2    Badar, J.3    Singh, C.4    Kuliopulos, A.5
  • 19
    • 4644338086 scopus 로고    scopus 로고
    • Differences in gene expression profiles of diabetic and nondiabetic patients undergoing cardiopulmonary bypass and cardioplegic arrest
    • P. Voisine, M. Ruel, T.A. Khan Differences in gene expression profiles of diabetic and nondiabetic patients undergoing cardiopulmonary bypass and cardioplegic arrest Circulation 110 suppl II 2004 II280 II286
    • (2004) Circulation , vol.110 , Issue.2 SUPPL.
    • Voisine, P.1    Ruel, M.2    Khan, T.A.3
  • 20
    • 0041414587 scopus 로고    scopus 로고
    • The -174G/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication?
    • M. Gaudino, F. Andreotti, R. Zamparelli The -174G/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication? Circulation 108 suppl II 2003 II195 II199
    • (2003) Circulation , vol.108 , Issue.2 SUPPL.
    • Gaudino, M.1    Andreotti, F.2    Zamparelli, R.3
  • 21
    • 0035884847 scopus 로고    scopus 로고
    • The IL-6-soluble IL-6Ralpha autocrine loop of endothelial activation as an intermediate between acute and chronic inflammation: An experimental model involving thrombin
    • V. Marin, F.A. Montero-Julian, S. Gres The IL-6-soluble IL-6Ralpha autocrine loop of endothelial activation as an intermediate between acute and chronic inflammation an experimental model involving thrombin J Immunol 167 2001 3435 3442
    • (2001) J Immunol , vol.167 , pp. 3435-3442
    • Marin, V.1    Montero-Julian, F.A.2    Gres, S.3
  • 23
    • 7544236615 scopus 로고    scopus 로고
    • Clinical inhibition of the seven-transmembrane thrombin receptor (PAR1) by intravenous aprotinin during cardiothoracic surgery
    • J.R.S. Day, P.P. Punjabi, D.O. Haskard, R.C. Landis, K.M. Taylor Clinical inhibition of the seven-transmembrane thrombin receptor (PAR1) by intravenous aprotinin during cardiothoracic surgery Circulation 110 2004 2597 2600
    • (2004) Circulation , vol.110 , pp. 2597-2600
    • Day, J.R.S.1    Punjabi, P.P.2    Haskard, D.O.3    Landis, R.C.4    Taylor, K.M.5
  • 25
    • 0347951196 scopus 로고    scopus 로고
    • The hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: Antiinflammatory monocyte-macrophages responses in vitro, in resolving skin blisters in vivo and postoperatively following cardio-pulmonary bypass
    • P. Philippidis, J.C. Mason, B.J. Evans, K.M. Taylor, D.O. Haskard, R.C. Landis The hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis antiinflammatory monocyte-macrophages responses in vitro, in resolving skin blisters in vivo and postoperatively following cardio-pulmonary bypass Circ Res 94 2004 119 126
    • (2004) Circ Res , vol.94 , pp. 119-126
    • Philippidis, P.1    Mason, J.C.2    Evans, B.J.3    Taylor, K.M.4    Haskard, D.O.5    Landis, R.C.6
  • 26
    • 0028972012 scopus 로고
    • Aprotinin and methylprednisolone equally blunt neutrophil cardiopulmonary bypass-induced inflammation in humans
    • G.E. Hill, A. Alonso, J.R. Spurzem, A.H. Stammers, R.A. Robbins Aprotinin and methylprednisolone equally blunt neutrophil cardiopulmonary bypass-induced inflammation in humans J Thorac Cardiovasc Surg 110 1995 1658 1662
    • (1995) J Thorac Cardiovasc Surg , vol.110 , pp. 1658-1662
    • Hill, G.E.1    Alonso, A.2    Spurzem, J.R.3    Stammers, A.H.4    Robbins, R.A.5
  • 27
    • 0032167537 scopus 로고    scopus 로고
    • Modifying risk for extracorporeal circulation: Trial of four antiinflammatory strategies
    • J.P. Gott, W.A. Cooper, F.E. Schmidt Jr Modifying risk for extracorporeal circulation trial of four antiinflammatory strategies Ann Thorac Surg 66 1998 747 753
    • (1998) Ann Thorac Surg , vol.66 , pp. 747-753
    • Gott, J.P.1    Cooper, W.A.2    Schmidt Jr., F.E.3
  • 28
    • 0027255011 scopus 로고
    • Aprotinin inhibits the contact, neutrophil, and platelet activation systems during simulated extracorporeal perfusion
    • Y.T. Wachtfogel, U. Kucich, C.E. Hack Aprotinin inhibits the contact, neutrophil, and platelet activation systems during simulated extracorporeal perfusion J Thorac Cardiovasc Surg 106 1993 1 10
    • (1993) J Thorac Cardiovasc Surg , vol.106 , pp. 1-10
    • Wachtfogel, Y.T.1    Kucich, U.2    Hack, C.E.3
  • 30
    • 0033854191 scopus 로고    scopus 로고
    • An anti-inflammatory property of aprotinin discovered at the level of leukocyte extravasation
    • G. Asimakopoulos, R. Thompson, S. Nourshargh An anti-inflammatory property of aprotinin discovered at the level of leukocyte extravasation J Thorac Cardiovasc Surg 120 2000 361 369
    • (2000) J Thorac Cardiovasc Surg , vol.120 , pp. 361-369
    • Asimakopoulos, G.1    Thompson, R.2    Nourshargh, S.3
  • 32
    • 0037235417 scopus 로고    scopus 로고
    • Aprotinin inhibits leukocyte-endothelial cell interactions after hemorrhage and reperfusion
    • D. Pruefer, J. Makowski, M. Dahm Aprotinin inhibits leukocyte-endothelial cell interactions after hemorrhage and reperfusion Ann Thorac Surg 75 2003 210 215
    • (2003) Ann Thorac Surg , vol.75 , pp. 210-215
    • Pruefer, D.1    Makowski, J.2    Dahm, M.3
  • 33
    • 0029983976 scopus 로고    scopus 로고
    • Aprotinin reduces interleukin-8 production and lung neutrophil accumulation after cardiopulmonary bypass
    • G.E. Hill, R. Pohorecki, A. Alonso, S.I. Rennard, R.A. Robbins Aprotinin reduces interleukin-8 production and lung neutrophil accumulation after cardiopulmonary bypass Anesth Analg 83 1996 696 700
    • (1996) Anesth Analg , vol.83 , pp. 696-700
    • Hill, G.E.1    Pohorecki, R.2    Alonso, A.3    Rennard, S.I.4    Robbins, R.A.5
  • 34
    • 0026753845 scopus 로고
    • Aprotinin can inhibit the proteolytic activity of thrombin. a fluorescence and an enzymatic study
    • D. Pintigny, J. Dachary-Prigent Aprotinin can inhibit the proteolytic activity of thrombin. A fluorescence and an enzymatic study Eur J Biochem 207 1992 89 95
    • (1992) Eur J Biochem , vol.207 , pp. 89-95
    • Pintigny, D.1    Dachary-Prigent, J.2
  • 35
    • 0037383552 scopus 로고    scopus 로고
    • Synergistic effect of -174 G/C polymorphism of the interleukin-6 gene promoter and 469 E/K polymorphism of the intercellular adhesion molecule-1 gene in Italian patients with history of ischemic stroke
    • R. Pola, A. Flex, E. Gaetani, R. Flore, M. Serricchio, P. Pola Synergistic effect of -174 G/C polymorphism of the interleukin-6 gene promoter and 469 E/K polymorphism of the intercellular adhesion molecule-1 gene in Italian patients with history of ischemic stroke Stroke 34 2003 881 885
    • (2003) Stroke , vol.34 , pp. 881-885
    • Pola, R.1    Flex, A.2    Gaetani, E.3    Flore, R.4    Serricchio, M.5    Pola, P.6
  • 36
    • 0037335934 scopus 로고    scopus 로고
    • Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke
    • N. Vila, J. Castillo, A. Davalos, A. Esteve, A.M. Planas, A. Chamorro Levels of anti-inflammatory cytokines and neurological worsening in acute ischemic stroke Stroke 34 2003 671 675
    • (2003) Stroke , vol.34 , pp. 671-675
    • Vila, N.1    Castillo, J.2    Davalos, A.3    Esteve, A.4    Planas, A.M.5    Chamorro, A.6
  • 37
    • 4444380033 scopus 로고    scopus 로고
    • Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: A systematic review and meta-analysis of randomized clinical trials
    • A. Sedrakyan, T. Treasure, J.A. Elefteriades Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery a systematic review and meta-analysis of randomized clinical trials J Thorac Cardiovasc Surg 128 2004 442 448
    • (2004) J Thorac Cardiovasc Surg , vol.128 , pp. 442-448
    • Sedrakyan, A.1    Treasure, T.2    Elefteriades, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.