Fibrinolytic therapy in spontaneous intraventricular haemorrhage: Efficacy and safety of the treatment

British Journal of Neurosurgery

Volumn 22, Issue 2, 2008, Pages 269-274

  Torres, A ^a,b   Plans, G ^a   Martino, J ^a   Godino, O ^a   Garcia, I ^a   Gracia, B ^a   Acebes, J J ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^b Department of Neurosurgery ^*  (Spain)

Author keywords

Complications; Intraventricular haemorrhage; Outcome; Treatment

Indexed keywords

UROKINASE;

ADULT; AGED; ANASTOMOSIS; ARTICLE; BRAIN HEMORRHAGE; BRAIN VENTRICULITIS; CAUSE OF DEATH; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG INFUSION; DRUG SAFETY; FEMALE; FIBRINOLYTIC THERAPY; GLASGOW COMA SCALE; HUMAN; INTRACRANIAL HYPERTENSION; MALE; MEDICAL RECORD; MORTALITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECURRENT DISEASE; RESPIRATORY TRACT INFECTION; SEIZURE; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; CEREBRAL VENTRICLES; DRAINAGE; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; INTRACRANIAL HEMORRHAGES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; THROMBOLYTIC THERAPY; TREATMENT OUTCOME; URINARY PLASMINOGEN ACTIVATOR;

EID: 40949140609     PISSN: 02688697     EISSN: 1360046X     Source Type: Journal    
DOI: 10.1080/02688690701834494     Document Type: Article

References (23)

1. Fountas KN, Kapsalaki EZ, Parish DC, et al. Intraventricular administration of rt-PA in patients with intraventricular haemorrhage. South Med J 2005;98(8):767-73.
2. Naff NJ, Hanley DF, Keyl PM, et al. Intraventricular thrombolysis speeds blood clot resolution: results of a pilot, prospective, randomized, double-blind, controlled trial. Neurosurgery 2003;54:577-84.
3. Coplin WM, Vinas FC, Agris JM, et al. A cohort study of the safety and feasibility of intraventricular urokinase for nonaneurysmal spontaneous intraventricular haemorrhage. Stroke 1998;29:1573-9.
4. Naff NJ, Carhuapoma JR, Williams MA, et al. Treatment of intraventricular haemorrhage with urokinase. Effects on 30-day survival. Stroke 2000;31:841-7.
5. Graeb DA, Robertson WD, Lapointe JS, Nugent RA, Harrison PB. Computed tomographic diagnosis of intraventricular haemorrhage: etiology and prognosis. Radiology 1982;143:91-6.
6. Mayfrank L, Lippitz B, Groth M, Bertalanffy H, Gilsbach JM. Effect of recombinant tissue plasminogen activator on clot lysis and ventricular dilatation in the treatment of severe intraventricular haemorrhage. Acta Neurochir (Wien) 1993;122:32-8.
7. Ruscadella J, Peiró A. Prognostic factors in intraparenchymatous haematoma with ventricular haemorrhage. Neuroradiology 1986;28:34-7.
8. Findlay JM, Wong JH. Clinical aspects of intraventricular haemorrhage. Cited in: Welch KMA, Kanter RK, Weiner LB, Patti M, Robson LK. Infectious complications and duration of intracranial pressure monitoring. Crit Care Med 1997;13:837-9.
9. Aucoin PJ, Kotilainen HR, Gantz NM, et al. Intracranial pressure monitors: epidemiologic study of risk factors and infection. Am J Med 1986;80:369-76.
10. Rosner MJ, Becker DP. ICP monitoring: complications and associated factors. Clin Neurosurg 1976;23:494-519.
11. Schultz M, Moore K, Foote AW. Bacterial ventriculitis and duration of ventriculostomy catheter insertion. J Neurosci Nurs 1993;25:158-64.
12. Adams RE, Diringer MN. Response to external ventricular drainage in spontaneous intracerebral haemorrhage with hydrocephalus. Neurology 1998;50:519-23.
13. Lee KR, Betz AL, Kim S, Keep RF, Hoff JT. The role of the coagulation cascade in brain edema formation after intracerebral haemorrhage. Acta Neurchir 1996;138:396-401.
14. Nishino A, Suzuki M, Motohashi O, et al. Thrombin may contribute to the pathophysiology of central nervous system injury. J Neurotrauma 1993;10:167-79.
15. Yang GY, Betz AL, Hoff JT. The effects of blood or plasma clots on brain edema in the rat after intracerebral haemorrhage. Acta Neurochir 1994;60:555-7.
16. Pang D, Sclabassi RJ, Horton JA. Lysis of intraventricular blood clot with urokinase in a canine model, part 2: in vivo safety study of intraventricular urokinase. Neurosurgery 1986;19:547-52.
17. Pang D, Sclabassi RJ, Horton JA. Lysis of intraventricular blood clot with urokinase in a canine model, part 3: effects of intraventricular urokinase on clot lysis and posthemorrhagic hydrocephalus. Neurosurgery 1986;19:553-72.
18. Pang D, Sclabassi RJ, Horton JA. Lysis of intraventricular blood clot with urokinase in a canine model, part 1: canine intraventricular cast model. Neurosurgery 1986;19:540-6.
19. Findlay JM, Jacka MJ. Cohort study of intraventricular thrombolysis with recombinant tissue plasminogen activator for aneurysmal intraventricular haemorrhage. Neurosurgery 2004;55:532-7.
20. Todo T, Usui M, Takakura K. Treatment of severe intraventricular haemorrhage by intraventricular infusion of urokinase. J Neurosurg 1991;74:81-6.
21. Vereecken KK, Van Havenbergh T, De Beuckelaar W, Parizel PM, Jorens PG. Treatment of intraventricular haemorrhage with intraventricular administration of recombinant tissue plasminogen activator. A clinical study of 18 cases. Clin Neurol Neurosurg 2005;108:451-5.
22. Gubucz I, Kakuk I, Major O, et al. Effectiveness and safety of intraventricular fibrinolysis in secondary intraventricular hemorrhages (a prospective, randomized study). Orv Hetil 2004;145(31):1609-15.
23. Caplan LR, Reis DJ, Siesjo BK, Weir B (Eds) Prim on cerebrovascular diseases. San Diego: Academic Press, 437-46.