Treatment of intraventricular hemorrhage with intraventricular administration of recombinant tissue plasminogen activator. A clinical study of 18 cases

Clinical Neurology and Neurosurgery

Volumn 108, Issue 5, 2006, Pages 451-455

  Vereecken, Kevin K ^a   Van Havenbergh, Tony ^a   De Beuckelaar, Wim ^a   Parizel, Paul M ^a   Jorens, Philippe G ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Aneurysm; Intraventricular hemorrhage; Recombinant tissue plasminogen activator (rtPA); Subarachnoidal hemorrhage; Thrombolysis

Indexed keywords

ALTEPLASE; CEFAZOLIN;

ADULT; AGED; ARACHNOIDITIS; ARTICLE; BRAIN EDEMA; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN VENTRICULITIS; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; FEMALE; HUMAN; MALE; SCORING SYSTEM; TREATMENT OUTCOME; UNIVERSITY HOSPITAL;

ADULT; AGED; CEREBRAL VENTRICLES; FEMALE; FIBRINOLYTIC AGENTS; FUNCTIONAL LATERALITY; GLASGOW COMA SCALE; HUMANS; MALE; MIDDLE AGED; SUBARACHNOID HEMORRHAGE; TISSUE PLASMINOGEN ACTIVATOR; VENTRICULOSTOMY;

EID: 33646565003     PISSN: 03038467     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clineuro.2005.07.006     Document Type: Article

References (40)

1. Daverat P., Castel J.P., and Dartigues J.F. Death and functional outcome after spontaneous intracerebral hemorrhage. A prospective study of 166 cases using multivariate analysis. Stroke 22 (1991) 1-6
2. Adams H.P., Torner J.C., and Kassell N.F. Intraventricular hemorrhage among patients with recently ruptured aneurysms: a report of the cooperative aneurysm study. Stroke 23 (1992) 140-145
3. Hyashi M., Handa Y., and Kobayashi H. Prognosis of intraventricular hemorrhage due to rupture of intracranial aneurysm. Zentralbl Neurochir 50 (1989) 132-137
4. Little J.R., Blomquist C.A., and Ethier R. Intraventricular hemorrhage in adults. Surg Neurol 8 (1977) 143-149
5. Lee K.R., Betz A.L., Kim S., Keep R.F., and Hoff J.T. The role of the coagulation cascade in brain edema formation after intracerebral hemorrhage. Acta Neurochir 138 (1996) 396-401
6. Broderick J.P., Brott T.G., Duldner J.E., Tomsick T., and Huster G. Volume of intracerebral hemorrhage. Stroke 24 (1993) 987-993
7. Le Roux P.D., Haglund M.M., Newell D.W., Grady M.S., and Winn H.R. Intraventricular hemorrhage in blunt head trauma: an analysis of 43 cases. Neurosurgery 31 (1992) 678-685
8. Steinke W., Sacco R.L., Mohr J.P., Foulkes M.A., Tatemichi T.K., Wolf P.A., et al. Thalamic stroke: presentation of infarcts and hemorrhages. Arch Neurol 49 (1992) 703-710
9. Broderick J.P., Brott T.G., Duldner J.E., Tomsick T., and Huster G. Volume of intraventricular hemorrhage. Stroke 24 (1993) 987-993
10. Young W.B., Lee K.P., and Pessin M.S. Prognostic significance of ventricular blood in supratentorial hemorrhage: a volumetric study. Neurology 40 (1990) 616-619
11. Shapiro S.A., Campbell R.L., and Scully T. Hemorrhagic dilation of the fourth ventricle: an ominous predictor. J Neurosurg 80 (1994) 805-809
12. Mayfrank L., Lippitz B., Groth M., Bertalanffy H., and Gilsbach J.M. Effect of recombinant tissue plasminogen activator on clot lysis and ventricular dilation in the treatment of intraventricular haemorrhage. Acta Neurochir 122 (1993) 32-38
13. Andrews C.O., and Engelhard H.H. Fibrinolytic therapy in intraventricular hemorrhage. Ann. Pharmacother. 55 (2001) 1435-1447
14. Jenneet B., and Bond M. Assessment of outcome after severe brain damage: a practical scale. Lancet i (1975) 480-484
15. Findlay J.M., and Wong J.H. Clinical aspects of intraventricular hemorrhage. In: Welch K.M.A., Caplan L.R., Reis D., and Siesjö B.J. (Eds). Primer on cerebrovascular diseases (1997), Academic Press 437-446
16. Jichici D., and Franck J.I. Thrombolytic therapy in neurointensive care. Crit Care Clin. 13 (1997) 201-227
17. Keller T.M., Corkill G., and Ellis W.G. Persistent isodense intraventricular hematoma caused by intraventricular saccular aneurysm. Surg Neurol 13 (1980) 177-180
18. Yamamoto Y., and Waga S. Persistent intraventricular hematoma following ruptured aneurysm. Surg Neurol 17 (1982) 301-303
19. Parizel P.M., Makkat S., Van Miert E., Van Goethem J.W., van den Hauwe L., and De Schepper A.M. Intracranial hemorrhage: principles of CT and MRI interpretation. Eur Radiol 11 (2001) 1770-1783
20. Yi J.S., Kim Y.H., and Koh J.Y. Infarct reduction in rats following intraventricular administration of either tissue plasminogen activator (tPA) or its non-protease mutant S478A-tPA. Exp Neurol 189 2 (2004) 354-360
21. Mayfrank L., Kissler J., Raoofi P., et al. Ventricular dilatation in experimental intraventricular hemorrhage in pigs. Stroke 28 (1997) 141-148
22. Tuhrim S., Horowitz D., Sacher M., and Godbold J. Volume of ventricular blood is an important determinant of outcome in supratentorial intracerebral hemorrhage. Crit Care Med 27 (1999) 617-621
23. Mayer S.A., Kessler D.B., Van Hurtum R.L., et al. Effect of intraventricular blood on global cortical perfusion in acute intracerebral hemorrhage: a single photon emission computed tomographic study. Ann Neurol 38 (1995) 228 (Abstract)
24. Lee M.W., Pang K.Y., Ho W.W., and Wong C.K. Outcome analysis of intraventricular thrombolytic therapy for intraventricular hemorrhage. Hong Kong Med J 9 (2003) 335-340
25. Naff N.J., Hanley D.F., Keyl P.M., Tuhrim S., Kraut M., Bederson J., et al. Intraventricular thrombolysis speeds blood clot resolution: results of a pilot, prospective, randomized double-blind, controlled trial. Neurosurgery 54 3 (2004) 577-583
26. Findlay J.M., Weir B.K.A., and Stollery D.A. Lysis of intraventricular haematoma with tissue plasminogen activator. Case report. J Neurosurg 74 (1991) 803-807
27. Findlay J.M., Grace M.G.A., and Weir B.K.A. Treatment of intraventricular hemorrhage with tissue plasminogen activator. Neurosurgery 32 (1993) 941-947
28. Rohde V., Schaller C., and Hassler W.E. Intraventricular recombinant tissue plasminogen activator for lysis of intraventricular hemorrhage. J Neurol Neurosurg Psychiatry 58 (1995) 447-451
29. Goh K.Y., and Poon W.S. Recombinant tissue plasminogen for the treatment of spontaneous adult intraventricular hemorrhage. Surg Neurol 50 (1998) 526-531
30. Grabb P.A. Traumatic intraventricular hemorrhage treated with intraventricular recombinant tissue plasminogen activator: technical case report. Neurosurgery 43 (1998) 966-969
31. Slavin K.W., Ausman J.I., Charbel F.T., Andrews C., Misra M., and Munoz L.F. Results of the treatment of intraventricular hemorrhage with recombinant tissue plasminogen activator in a series of 10 patients. J Neurosurg 88 (1998) 194A (Abstract)
32. Mayfrank L., Rhode V., and Gilsbach J.M. Fibrinolytic treatment of intraventricular haemorrhage preceding surgical repair of ruptured aneurysms and arteriovenous malformations. Br J Neurosurg 13 (1999) 128-131
33. Azmi-Ghadimi H., Heary R.F., Farkas J.E., and Hunt C.D. Use of intraventricular tissue plasminogen activator and Guglielmi detachable coiling for the acute treatment of casted ventricles from cerebral aneurysm hemorrhage: two technical case reports. Neurosurgery 50 2 (2002) 421-424
34. Deutsch H., Rodriguez J.C., and Titton R.L. Lower dose intraventricular tPA fibrinolysis: case report. Surg Neurol 61 (2004) 460-463
35. Findlay J.M., and Jacka J. Cohort study of intraventricular thrombolysis with recombinant tissue plasminogen activator for aneurysmal intraventricular hemorrhage. Neurosurgery 55 (2004) 532-538
36. Varelas P.N., Rickert M., Cusick J., Hacein-Bay L., Sinson G., Torbey M., et al. Intraventricular hemorrhage after aneurysmal subarachnoid hemorrhage: pilot study of treatment with intraventricular tissue plasminogen activator. Neurosurgery 56 (2005) 205-213
37. Whitelaw A., Christie S., and Pople I. Transforming growth factor β-1: a possible signal molecule for post-haemorrhagic hydrocephalus?. Pediatr Res 46 (1999) 576-580
38. Wang X., Asahi M., and Lo E.H. Tissue type plasminogen activator amplifies hemoglobin-indiced neurotoxicity in rat neuronal cultures. Neurosci Lett 274 (1999) 79-82
39. Wang X., Lee S.R., Arai K., Lee S.R., Tsuji K., Rebeck G.W., et al. Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator. Nat Med 9 (2003) 1313-1317
40. Wang Y.C., Lin C.W., Shen C.C., Lai S.C., and Kuo J.S. Tissue plasminogen activator for the treatment of intraventricular hematoma: the dose-effect relationship. J Neurol Sci 202 (2002) 35-41