Endogenous Pancreatic Protease Activity and Methods for Impeding Their Function

Transplantation Proceedings

Volumn 40, Issue 2, 2008, Pages 355-357

  Umeadi, C ^a   Bentsi Barnes, K ^a   Kandeel, F ^a   Al Abdullah, I H ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; APROTININ; CHYMOTRYPSIN; ELASTASE; ENZYME; INSULIN; LIBERASE; PROTEINASE; SERINE PROTEINASE INHIBITOR; THERMOLYSIN; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; CELL FUNCTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INCUBATION TIME; INSULIN RELEASE; PANCREAS ISLET; PRIORITY JOURNAL;

APROTININ; CHYMOTRYPSIN; HUMANS; KINETICS; PANCREAS; PEPTIDE HYDROLASES; PHOSPHOPYRUVATE HYDRATASE; PROTEASE INHIBITORS; SERINE PROTEINASE INHIBITORS; SULFONES; TRYPSIN INHIBITORS;

EID: 40949129202     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2008.01.033     Document Type: Article

References (8)

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3. Lakey J.R., Helms L.M., Kin T., et al. Serine-protease inhibition during islet isolation increases islet yield from human pancreases with prolonged ischemia. Transplantation 72 (2001) 565
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5. Rose N.L., Palcic M.M., Shapiro A.M.J., et al. Endogenous pancreatic enzyme activity levels show no significant effect on human islet isolation yield. Cell Transplantation 13 (2004) 153
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7. Noguchi H., Ueda M., Nakai Y., et al. Modified two-layer preservation method (M-Kyoto/PFC) improves islet yields in islet isolation. Am J Transplant 6 (2006) 496
8. Pefabloc S.C., and Pefabloc S.C. PLus for convinient and reliable serine protease inhibition biochemica [Product Article]. www.roche-applied-science.com Accessed October 3, 2006