Effects of colloid and crystalloid solutions on endogenous activation of fibrinolysis and resistance of polymerized fibrin to recombinant tissue plasminogen activator added ex vivo

British Journal of Anaesthesia

Volumn 100, Issue 3, 2008, Pages 307-314

  Mittermayr, M ^a   Streif, W ^a   Haas, T ^a   Fries, D ^a   Velik Salchner, C ^a   Klingler, A ^b   Innerhofer, P ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b ASSIGN DATA MANAGEMENT AND BIOSTATISTICS GMBH   (Austria)

Author keywords

Blood, coagulation; Blood, haemodilution; Measurement techniques, thrombelastograph

Indexed keywords

ALTEPLASE; FENTANYL; FIBRIN; GELATIN; GELOFUSIN; HETASTARCH; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROPOFOL; RINGER LACTATE SOLUTION; ROCURONIUM; SEVOFLURANE; TISSUE PLASMINOGEN ACTIVATOR; BIOLOGICAL MARKER; ISOTONIC SOLUTION; PLASMA SUBSTITUTE; RINGER'S LACTATE; SERPINE1 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ADULT; ANESTHESIA INDUCTION; ARTICLE; COLLOID; CONTROLLED STUDY; CRYSTALLOID; FIBRINOLYSIS; HUMAN; IN VIVO STUDY; MAJOR CLINICAL STUDY; ORTHOPEDIC SURGERY; POLYMERIZATION; PRIORITY JOURNAL; THROMBOELASTOGRAPHY; ADOLESCENT; AGED; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; METABOLISM; METHODOLOGY; MIDDLE AGED; PEROPERATIVE CARE; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; FIBRIN; FIBRINOLYSIS; GELATIN; HETASTARCH; HUMANS; INTRAOPERATIVE CARE; ISOTONIC SOLUTIONS; MIDDLE AGED; ORTHOPEDIC PROCEDURES; PLASMA SUBSTITUTES; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBELASTOGRAPHY; TISSUE PLASMINOGEN ACTIVATOR;

EID: 40949123740     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aem363     Document Type: Article

References (14)

1. Mittermayr M, Streif W, Haas T, et al. Hemostatic changes after crystalloid or colloid fluid administration during major orthopaedic surgery: the role of fibrinogen administration. Anesth Analg 2007; 105: 905-17
2. Boldt J, Haisch G, Suttner S, et al. Effects of a new modified, balanced hydroxyethyl starch preparation (Hextend) on measures of coagulation. Br J Anaesth 2002; 89: 722-8
3. Nielsen VG. Hemodilution modulates the time of onset and rate of fibrinolysis in human and rabbit plasma. J Heart Lung Transplant 2006; 25: 1344-52
4. de Jonge E, Levi M. Effects of different plasma substitutes on blood coagulation: a comparative review. Crit Care Med 2001; 29: 1261-7
5. Fries D, Innerhofer P, Klingler A, et al. The effect of the combined administration of colloids and lactated Ringer's solution on the coagulation system: an in vitro study using thrombelastograph coagulation analysis (ROTEG). Anesth Analg 2002; 94: 1280-7; table of contents
6. Jones SB, Whitten CW, Despotis GJ, et al. The influence of crystalloid and colloid replacement solutions in acute normovolemic hemodilution: a preliminary survey of hemostatic markers. Anesth Analg 2003; 96: 363-8; table of contents
7. Innerhofer P, Fries D, Margreiter J, et al. The effects of perioperatively administered colloids and crystalloids on primary platelet-mediated hemostasis and clot formation. Anesth Analg 2002; 95: 858-65; table of contents
8. Nielsen VG. Colloids decrease clot propagation and strength: role of factor XIII-fibrin polymer and thrombin-fibrinogen interactions. Acta Anaesthesiol Scand 2005; 49: 1163-71
9. Fries D, Streif W, Margreiter J, et al. The effects of perioperatively administered crystalloids and colloids on concentrations of molecular markers of activated coagulation and fibrinolysis. Blood Coagul Fibrinolysis 2004; 15: 213-9
10. Despotis GJ, Avidan MS, Hogue CW, Jr. Mechanisms and attenuation of hemostatic activation during extracorporeal circulation. Ann Thorac Surg 2001; 72: S1821-31
11. Livingston ER, Fisher CA, Bibidakis EJ, et al. Increased activation of the coagulation and fibrinolytic systems leads to hemorrhagic complications during left ventricular assist implantation. Circulation 1996; 94: II227-34
12. Kapsch DN, Metzler M, Harrington M, et al. Fibrinolytic response to trauma. Surgery 1984; 95: 473-8
13. Senzolo M, Burra P, Cholongitas E, et al. New insights into the coagulopathy of liver disease and liver transplantation. World J Gastroenterol 2006; 12: 7725-36
14. Kuitunen AH, Suojaranta-Ylinen RT, Kukkonen SI, et al. Tranexamic acid does not correct the haemostatic impairment caused by hydroxyethyl starch (200 kDa/0.5) after cardiac surgery. Blood Coagul Fibrinolysis 2006; 17: 639-45