Time Course Analysis of the Effects of Botulinum Toxin Type A on Elbow Spasticity Based on Biomechanic and Electromyographic Parameters

Archives of Physical Medicine and Rehabilitation

Volumn 89, Issue 4, 2008, Pages 692-699

  Lee, Hsin Min ^a   Chen, Jia Jin Jason ^b   Wu, Yi Ning ^b   Wang, Yu Lin ^c   Huang, Sheng Chih ^b   Piotrkiewicz, Maria ^d  

^a I SHOU UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

^d INSTITUTE OF BIOCYBERNETICS AND BIOMEDICAL ENGINEERING   (Poland)

Author keywords

Botulinum toxin type A; Muscle spasticity; Rehabilitation

Indexed keywords

BOTULINUM TOXIN A;

ADULT; AGED; ARM MUSCLE; ARTICLE; BICEPS BRACHII MUSCLE; BIOMECHANICS; CLINICAL ARTICLE; CONTROLLED STUDY; DEVICE; DRUG EFFECT; ELBOW DISEASE; ELECTROMYOGRAPHY; FEMALE; HUMAN; MALE; MODIFIED ASHWORTH SCALE; MUSCLE HYPERTONIA; MYOTATIC REFLEX; OUTCOME ASSESSMENT; QUANTITATIVE ANALYSIS; RATING SCALE; SPASTICITY; STATISTICAL ANALYSIS; STROKE; TIME SERIES ANALYSIS; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE; VELOCITY; VISCOSITY;

ADULT; AGED; ANALYSIS OF VARIANCE; BIOMECHANICS; BOTULINUM TOXIN TYPE A; CHRONIC DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ELBOW JOINT; ELECTROMYOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, INTRAMUSCULAR; MALE; MIDDLE AGED; MUSCLE SPASTICITY; PROBABILITY; PROSPECTIVE STUDIES; RANGE OF MOTION, ARTICULAR; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; STROKE; TIME FACTORS; TREATMENT OUTCOME; UPPER EXTREMITY;

EID: 40949119053     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apmr.2007.08.166     Document Type: Article

References (44)

1. Bakheit A.M., Maynard V.A., Curnow J., Hudson N., and Kodapala S. The relation between Ashworth scale scores and the excitability of the alpha motor neurones in patients with post-stroke muscle spasticity. J Neurol Neurosurg Psychiatry 74 (2003) 646-648
2. Mauritz K.H. Gait training in hemiplegia. Eur J Neurol 9 (2002) 23-29
3. Mayer N.H., Esquenazi A., and Childers M.K. Common patterns of clinical motor dysfunction. Muscle Nerve Suppl 6 (1997) S21-S35
4. Hurvitz E.A., Conti G.E., and Brown S.H. Changes in movement characteristics of the spastic upper extremity after botulinum toxin injection. Arch Phys Med Rehabil 84 (2003) 444-454
5. Pandyan A.D., Vuadens P., van Wijck F.M., Stark S., Johnson G.R., and Barnes M.P. Are we underestimating the clinical efficacy of botulinum toxin (type A)?. Quantifying changes in spasticity, strength and upper limb function after injections of Botox to the elbow flexors in a unilateral stroke population. Clin Rehabil 16 (2002) 654-660
6. Rousseaux M., Kozlowski O., and Froger J. Efficacy of botulinum toxin A in upper limb function of hemiplegic patients. J Neurol 249 (2002) 76-84
7. Aoki K.R. Pharmacology and immunology of botulinum toxin type A. Clin Dermatol 21 (2003) 476-480
8. van Kuijk A.A., Geurts A.C., Bevaart B.J., and van Limbeek J. Treatment of upper extremity spasticity in stroke patients by focal neuronal or neuromuscular blockade: a systematic review of the literature. J Rehabil Med 34 (2002) 51-61
9. Wang H.C., Hsieh L.F., Chi W.C., and Lou S.M. Effect of intramuscular botulinum toxin injection on upper limb spasticity in stroke patients. Am J Phys Med Rehabil 81 (2002) 272-278
10. Dolly O. Synaptic transmission: inhibition of neurotransmitter release by botulinum toxins. Headache 43 (2003) S16-S24
11. Setler P.E. Therapeutic use of botulinum toxins: background and history. Clin J Pain 18 6 Suppl (2002) S119-S124
12. Bohannon R.W., and Smith M.B. Interrater reliability of a modified Ashworth scale of muscle spasticity. Phys Ther 67 (1987) 206-207
13. Biering-Sorensen F., Nielsen J.B., and Klinge K. Spasticity-assessment: a review. Spinal Cord 44 (2006) 708-722
14. Gregson J.M., Leathley M., Moore A.P., Sharma A.K., Smith T.L., and Watkins C.L. Reliability of the Tone Assessment Scale and the modified Ashworth scale as clinical tools for assessing poststroke spasticity. Arch Phys Med Rehabil 80 (1999) 1013-1016
15. Haas B.M., Bergstrom E., Jamous A., and Bennie A. The inter rater reliability of the original and of the modified Ashworth scale for the assessment of spasticity in patients with spinal cord injury. Spinal Cord 34 (1996) 560-564
16. Johnson G.R. Outcome measures of spasticity. Eur J Neurol 9 (2002) 10-16
17. Lance J.W. Symposium synopsis. In: Feldman R.G., Young R.R., and Koella W.P. (Eds). Spasticity: disordered motor control (1980), Year Book Medical, Chicago 485-494
18. Sheean G. The pathophysiology of spasticity. Eur J Neurol 9 Suppl 1 (2002) 3-9
19. Broberg C., and Grimby G. Measurement of torque during passive and active ankle movements in patients with muscle hypertonia. A methodological study. Scand J Rehabil Med 9 Suppl (1983) 108-117
20. Firoozbakhsh K.K., Kunkel C.F., Scremin A.M., and Moneim M.S. Isokinetic dynamometric technique for spasticity assessment. Am J Phys Med Rehabil 72 (1993) 379-385
21. Lee H.M., Huang Y.Z., Chen J.J., and Hwang I.S. Quantitative analysis of the velocity related pathophysiology of spasticity and rigidity in the elbow flexors. J Neurol Neurosurg Psychiatry 72 (2002) 621-629
22. On A.Y., Kirazli Y., Kismali B., and Aksit R. Mechanisms of action of phenol block and botulinum toxin type A in relieving spasticity: electrophysiologic investigation and follow-up. Am J Phys Med Rehabil 78 (1999) 344-349
23. Kamper D.G., and Rymer W.Z. Quantitative features of the stretch response of extrinsic finger muscles in hemiparetic stroke. Muscle Nerve 23 (2000) 954-961
24. Voerman G.E., Gregoric M., and Hermens H.J. Neurophysiological methods for the assessment of spasticity: the Hoffmann reflex, the tendon reflex, and the stretch reflex. Disabil Rehabil 27 (2005) 33-68
25. Lee H.M., Chen J.J., Ju M.S., Lin C.C., and Poon P.P. Validation of portable muscle tone measurement device for quantifying velocity-dependent properties in elbow spasticity. J Electromyogr Kinesiol 14 (2004) 577-589
26. Chen J.J., Wu Y.N., Huang S.C., Lee H.M., and Wang Y.L. The use of a portable muscle tone measurement device to measure the effects of botulinum toxin type A on elbow flexor spasticity. Arch Phys Med Rehabil 86 (2005) 1655-1660
27. Sawner K.A., and LaVigne M.J. Brunnstrom's movement therapy in hemiplegia: a neurophysiological approach. 2nd ed. (1992), JB Lippincott, Philadelphia
28. Pandyan A.D., Johnson G.R., Price C.I., Curless R.H., Barnes M.P., and Rodgers H. A review of the properties and limitations of the Ashworth and modified Ashworth Scales as measures of spasticity. Clin Rehabil 13 (1999) 373-383
29. Bakheit A.M. Optimising the methods of evaluation of the effectiveness of botulinum toxin treatment of post-stroke muscle spasticity. J Neurol Neurosurg Psychiatry 75 (2004) 665-666
30. Simpson D.M., Alexander D.N., O'Brien C.F., et al. Botulinum toxin type A in the treatment of upper extremity spasticity: a randomized, double-blind, placebo-controlled trial. Neurology 46 (1996) 1306-1310
31. Stampacchia G., Bradaschia E., and Rossi B. Change of stretch reflex threshold in spasticity: effect of botulinum toxin injections. Arch Ital Biol 142 (2004) 265-273
32. Pauri F., Boffa L., Cassetta E., Pasqualetti P., and Rossini P.M. Botulinum toxin type-A treatment in spastic paraparesis: a neurophysiological study. J Neurol Sci 181 (2000) 89-97
33. Childers M.K., Brashear A., Jozefczyk P., et al. Dose-dependent response to intramuscular botulinum toxin type A for upper-limb spasticity in patients after a stroke. Arch Phys Med Rehabil 85 (2004) 1063-1069
34. Bhakta B.B., Cozens J.A., Chamberlain M.A., and Bamford J.M. Impact of botulinum toxin type A on disability and carer burden due to arm spasticity after stroke: a randomised double blind placebo controlled trial. [published erratum in: J Neurol Neurosurg Psychiatry 2001;70:821]. J Neurol Neurosurg Psychiatry 69 (2000) 217-221
35. Friedman A., Diamond M., Johnston M.V., and Daffner C. Effects of botulinum toxin A on upper limb spasticity in children with cerebral palsy. Am J Phys Med Rehabil 79 (2000) 53-59
36. Bakheit A.M., Pittock S., Moore A.P., et al. A randomized, double-blind, placebo-controlled study of the efficacy and safety of botulinum toxin type A in upper limb spasticity in patients with stroke. Eur J Neurol 8 (2001) 559-565
37. Lagalla G., Danni M., Reiter F., Ceravolo M.G., and Provinciali L. Post-stroke spasticity management with repeated botulinum toxin injections in the upper limb. Am J Phys Med Rehabil 79 (2000) 377-384
38. Wang R.Y., Tsai M.W., and Chan R.C. Effects of surface spinal cord stimulation on spasticity and quantitative assessment of muscle tone in hemiplegic patients. Am J Phys Med Rehabil 77 (1998) 282-287
39. Pisano F., Miscio G., Del Conte C., Pianca D., Candeloro E., and Colombo R. Quantitative measures of spasticity in post-stroke patients. Clin Neurophysiol 111 (2000) 1015-1022
40. Peng Q., Shah P., Selles R.W., Gaebler-Spira D.J., and Zhang L.Q. Measurement of ankle spasticity in children with cerebral palsy using a manual spasticity evaluator. Conf Proc IEEE Eng Med Biol Soc 7 (2004) 4896-4899
41. Ghika J., Wiegner A.W., Fang J.J., Davies L., Young R.R., and Growdon J.H. Portable system for quantifying motor abnormalities in Parkinson's disease. IEEE Trans Biomed Eng 40 (1993) 276-283
42. Prochazka A., Bennett D.J., Stephens M.J., et al. Measurement of rigidity in Parkinson's disease. Mov Disord 12 (1997) 24-32
43. Miscio G., Del Conte C., Pianca D., et al. Botulinum toxin in post-stroke patients: stiffness modifications and clinical implications. J Neurol 251 (2004) 189-196
44. Suputtitada A., and Suwanwela N.C. The lowest effective dose of botulinum A toxin in adult patients with upper limb spasticity. Disabil Rehabil 27 (2005) 176-184