Discovery and development of lamotrigine for bipolar disorder: A story of serendipity, clinical observations, risk taking, and persistence

Journal of Affective Disorders

Volumn 108, Issue 1-2, 2008, Pages 1-9

  Weisler, Richard H ^a   Calabrese, Joseph R ^b   Bowden, Charles L ^c   Ascher, John A ^d   DeVeaugh Geiss, Joseph ^e   Evoniuk, Gary ^d  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d GLAXOSMITHKLINE   (United States)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bipolar disorder; Carbamazepine; Lamotrigine; Lithium

Indexed keywords

AMFEBUTAMONE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; BUSPIRONE; CARBAMAZEPINE; CLONAZEPAM; LAMOTRIGINE; LEVOTHYROXINE; LITHIUM; LITHIUM CARBONATE; PLACEBO; VALPROIC ACID; VERAPAMIL;

BIPOLAR DISORDER; DIZZINESS; DRUG BIOAVAILABILITY; DRUG DOSE ESCALATION; DRUG HALF LIFE; ELECTROCONVULSIVE THERAPY; EPILEPSY; HEADACHE; HUMAN; NAUSEA; PHOTOTHERAPY; PHYSICIAN; PRIORITY JOURNAL; RASH; REVIEW; RISK FACTOR; SOMNOLENCE; TREMOR;

ADULT; AGED; ANTICONVULSANTS; ANTIMANIC AGENTS; BIPOLAR DISORDER; CARBAMAZEPINE; CLINICAL TRIALS AS TOPIC; DRUG INDUSTRY; EPILEPSY; FEMALE; HUMANS; LITHIUM CARBONATE; MALE; TRIAZINES;

EID: 40949108953     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2007.09.012     Document Type: Review

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