Screening for antidepressant, sedative and analgesic activities of novel fused thiophene derivatives

Acta Pharmaceutica

Volumn 58, Issue 1, 2008, Pages 1-14

  Wardakhan, Wagnat W ^a   Abdel Salam, Omar M E ^b   Elmegeed, Gamal A ^b  

^a NATIONAL ORGANIZATION FOR DRUG CONTROL AND RESEARCH NODCAR   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Analgesic; Antidepressant; Pyrimidine; Sedative; Tetrahydrobenzo b thiophene; Thiourea

Indexed keywords

1 IMINO 2 PHENYLAMINOCARBONYL 3 (ETHYLACETATOSULFYL) 6,7,8,9 TETRAHYDROBENZO[B]THIENO[2,3 D]PYRIMIDINE; 1 IMINO 2 PHENYLAMINOCARBONYL 4[H] 3 THIOXO 6,7,8,9 TETRAHYDROBENZO[B]THIENOL[2,3 D]PYRIMIDINE; 1 OXO 2 PHENYLAMINO CARBONYL 3 (ETHYLACETATOSULFYL) 6,7,8,9 TETRAHYDROBENZO[B]THIENO[2,3 D]PYRIMIDINE; 1 OXO 2 PHENYLAMINOCARBONYL 4[H] 3 THIOXO 6,7,8,9 TETRAHYDROBENZO[B]THIENO [2,3 D]PYRIMIDINE; 2 AMINO 4,5,6,7 TETRAHYDROBENZO[B]THIOPHENE DERIVATIVE; 3 BENZOYLMETHYLSULPHIDO 1 IMINO 2 PHENYLAMINOCARBONYL 6,7,8,9 TETRAHYDRIBENZO[B] THIENO[2,3 D] PYRIMIDINE; 3 BENZOYLMETHYLSULPHIDO 1 OXO 2 PHENYLAMINOCARBONYL 6,7,8,9 TETRAHYDROBENZO[B]THIENO[2,3 D]PYRIMIDINE; 3 CYANO 2 (N ETHOXYCARBONYLTHIOURYL) 4,5,6,7 TETRAHYDROBENZO[B]THIOPHENE; 3 CYANO 2 (N PHENYLAMINOCARBONYLTHIOURAYL 4,5,6,7 TETRAHYDROBENZO[B]THIOPHENE; 3 HYDRAZINO 2 PHENYLAMINOCARBONYL 1 IMINO 6,7,8,9 TETRAHYDROBENZO[B]THIENO[2,3 D]PYRIMIDINE; 3 HYDRAZINO 2 PHENYLAMINOCARBONYL 1 OXO 6,7,8,9 TETRAHYDROBENZO[B]THIENO[2,3 D]PYRIMIDINE; 3 PHENYLHYDRAZINO 2 PHENYLAMINOCARBONYL 1 IMINO 6,7,8,9 TETRAHYDROBENZO[B]THIENO[2,3 D]PYRIMIDINE; 3 PHENYLHYDRAZINO 2 PHENYLAMINOCARBONYL 1 OXO 6,7,8,9 TETRAHYDROBENZO[B]THIENO[2,3 D]PYRIMIDINE; ETHYL 1 IMINO 3 THIOXO 4[H] 6,7,8,9 TETRAHYDROBENZO[B]THIENO[2,3 D]PYRIMIDIN 2 CARBOXYLATE; ETHYL 1 OXO 3 THIOXO 4[H] 6,7,8,9 TETRAHYDROEBNZO[B]THIENO[2,3 D]PYRIMIDIN 2 CARBOXYLATE; ETHYL 2 (N ETHOXYCARBONYLTHIOURYL) 4,5,6,7 TETRAHYDROBENZO[B]THIOPHEN 3 CARBOXYLATE; ETHYL2 (N PHENYLAMINOCARBONYLTHIOURAYL 4,5,6,7 TETRAHYDROBENZO[B]THIOPHEN 3 CARBOXYLATE; IMIPRAMINE; INDOMETACIN; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG ACTIVITY; DRUG MEGADOSE; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 40949102165     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: 10.2478/v10007-007-0041-5     Document Type: Article

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