Expression of Pancreatitis Associated Proteins in Urothelium and Urinary Afferent Neurons Following Cyclophosphamide Induced Cystitis

Journal of Urology

Volumn 179, Issue 4, 2008, Pages 1603-1609

  Takahara, Yuki ^a   Suzuki, Akinobu ^a   Maeda, Mitsuyo ^a   Kawashima, Hidenori ^a   Nakatani, Tatsuya ^a   Kiyama, Hiroshi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

bladder; cystitis; inflammation; pancreatitis associated protein; rats; Sprague Dawley

Indexed keywords

CYCLOPHOSPHAMIDE; PANCREATITIS ASSOCIATED PROTEIN; PANCREATITIS ASSOCIATED PROTEIN 1; PANCREATITIS ASSOCIATED PROTEIN 3; PROTEIN; PROTEIN TYROSINE KINASE A; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYSTITIS; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE; SPINAL GANGLION; UROTHELIUM;

ANIMALS; ANTIGENS, NEOPLASM; CYCLOPHOSPHAMIDE; CYSTITIS; DISEASE MODELS, ANIMAL; FEMALE; GANGLIA, SPINAL; GENE EXPRESSION PROFILING; LECTINS, C-TYPE; NEURONS, AFFERENT; NOXAE; RATS; RATS, SPRAGUE-DAWLEY; TUMOR MARKERS, BIOLOGICAL; UROTHELIUM;

EID: 40849126321     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2007.11.034     Document Type: Article

References (20)

1. Terazono K., Yamamoto H., Takasawa S., Shiga K., Yonemura Y., Tochino Y., et al. A novel gene activated in regenerating islets. J Biol Chem 263 (1988) 2111
2. Namikawa K., Fukushima M., Murakami K., Suzuki A., Takasawa S., Okamoto H., et al. Expression of Reg/PAP family members during motor nerve regeneration in rat. Biochem Biophys Res Commun 332 (2005) 126
3. Drickamer K. Increasing diversity of animal lectin structures. Curr Opin Struct Biol 5 (1995) 612
4. Watanabe T., Yonemura Y., Yonekura H., Suzuki Y., Miyashita H., Sugiyama K., et al. Pancreatic beta-cell replication and amelioration of surgical diabetes by Reg protein. Proc Natl Acad Sci U S A 91 (1994) 3589
5. Iovanna J.L., Keim V., Bosshard A., Orelle B., Frigerio J.M., Dusetti N., et al. PAP, a pancreatic secretory protein induced during acute pancreatitis, is expressed in rat intestine. Am J Physiol 265 (1993) G611
6. Lasserre C., Christa L., Simon M.T., Vernier P., and Brechot C. A novel gene (HIP) activated in human primary liver cancer. Cancer Res 52 (1992) 5089
7. Livesey F.J., O'Brien J.A., Li M., Smith A.G., Murphy L.J., and Hunt S.P. A Schwann cell mitogen accompanying regeneration of motor neurons. Nature 390 (1997) 614
8. Christa L., Carnot F., Simon M.T., Levavasseur F., Stinnakre M.G., Lasserre C., et al. HIP/PAP is an adhesive protein expressed in hepatocarcinoma, normal Paneth, and pancreatic cells. Am J Physiol 271 (1996) G993
9. Ortiz E.M., Dusetti N.J., Vasseur S., Malka D., Bodeker H., Dagorn J.C., et al. The pancreatitis-associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis. Gastroenterology 114 (1998) 808
10. Nishimune H., Vasseur S., Wiese S., Birling M.C., Holtmann B., Sendtner M., et al. Reg-2 is a motoneuron neurotrophic factor and a signalling intermediate in the CNTF survival pathway. Nat Cell Biol 2 (2000) 906
11. Closa D., Motoo Y., and Iovanna J.L. Pancreatitis-associated protein: from a lectin to an anti-inflammatory cytokine. World J Gastroenterol 13 (2007) 170
12. Namikawa K., Okamoto T., Suzuki A., Konishi H., and Kiyama H. Pancreatitis-associated protein-III is a novel macrophage chemoattractant implicated in nerve regeneration. J Neurosci 26 (2006) 7460
13. Cash H.L., Whitham C.V., Behrendt C.L., and Hooper L.V. Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313 (2006) 1126
14. Gironella M., Folch-Puy E., LeGoffic A., Garcia S., Christa L., Smith A., et al. Experimental acute pancreatitis in PAP/HIP knock-out mice. Gut 56 (2007) 1091
15. Lieu H.T., Simon M.T., Nguyen-Khoa T., Kebede M., Cortes A., Tebar L., et al. Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice. Hepatology 44 (2006) 1452
16. Boucher M., Meen M., Codron J.P., Coudore F., Kemeny J.L., and Eschalier A. Cyclophosphamide-induced cystitis in freely-moving conscious rats: behavioral approach to a new model of visceral pain. J Urol 164 (2000) 203
17. Snider W.D., and McMahon S.B. Tackling pain at the source: new ideas about nociceptors. Neuron 20 (1998) 629
18. Birder L.A. More than just a barrier: urothelium as a drug target for urinary bladder pain. Am J Physiol Renal Physiol 289 (2005) F489
19. Averill S., McMahon S.B., Clary D.O., Reichardt L.F., and Priestley J.V. Immunocytochemical localization of trkA receptors in chemically identified subgroups of adult rat sensory neurons. Eur J Neurosci 7 (1995) 1484
20. Averill S., Davis D.R., Shortland P.J., Priestley J.V., and Hunt S.P. Dynamic pattern of reg-2 expression in rat sensory neurons after peripheral nerve injury. J Neurosci 22 (2002) 7493