Molecular basis of chromium insulin interactions

Biochemical and Biophysical Research Communications

Volumn 369, Issue 2, 2008, Pages 725-729

  Sreekanth, R ^a   Pattabhi, Vasantha ^a   Rajan, S S ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Chromium binding; Crystallography; Diabetes; Fluorescence; Insulin; UV Vis

Indexed keywords

CHROMIUM; DIAQUOETHYLENE BIS SALICYLIDENEIMINECHROMIUM; GLUTAMIC ACID; INSULIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; COMPLEX FORMATION; CRYSTALLOGRAPHY; DIABETES MELLITUS; DRUG BINDING; DRUG STRUCTURE; FLUORESCENCE; GLUCOSE METABOLISM; PRIORITY JOURNAL; ULTRAVIOLET SPECTROSCOPY;

BINDING SITES; CHROMIUM; COMPUTER SIMULATION; CRYSTALLOGRAPHY; INSULIN; MODELS, CHEMICAL; MODELS, MOLECULAR;

EID: 40849119675     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.02.083     Document Type: Article

References (31)

1. Broadhurst C.L., and Domenico P. Clinical studies on chromium picolinate supplementation in diabetes mellitus-a review. Diab. Technol. Ther. 8 (2006) 677-687
2. Balk E.M., Tatsioni A., Lichtenstein A.H., Lau J., and Pittas A.G. Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trials. Diabetes Care 30 (2007) 2154-2163
3. Havel P.J. A scientific review: the role of chromium in insulin resistance. Diabetes Educ. 30 3 Suppl. (2004) 1-14
4. Clodfelder B.J., and Vincent J.B. The time-dependent transport of chromium in adult rats from the bloodstream to the urine. J. Biol. Inorg. Chem. 10 (2005) 383-393
5. Vincent J.B. Mechanism of action of chromium: low-molecular-weight chromium-binding substance. J. Am. Coll. Nutr. 18 (1999) 6-12
6. Levina A., and Lay P.A. Mechanistic studies of relevance to the biological activities of chromium. Coord. Chem. Rev. 249 (2005) 281-298
7. Kim E., and Na K.J. Effect of sodium dichromate on carbohydrate metabolism. Toxicol. Appl. Pharmacol. 110 (1991) 251-258
8. Goto Y., and Kida K. Insulin-like action of chromate on glucose transport in isolated rat adipocytes. Jpn. J. Pharm. 67 (1995) 365-368
9. W.T. Cefalu, J.M. Martin, D. Wachtel, X.H. Zhang, Z.Q. Wang, Chromium picolinate supplementation increases insulin-stimulated Akt phosphorylation in vivo in skeletal muscle from subjects with type 2 diabetes, 18th Inter. Diab. Fed. Cong. August 24-29 (2003) Paris, France, Abstract 154.
10. Chen G., Liu P., Pattar G.R., Tackett L., Bhonagiri P., Strawbridge A.B., and Elmendorf J.S. Chromium activates GLUT4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism. Mol. Endocrinol. 20 (2006) 857-870
11. Jain S.K., and Kannan K. Chromium chloride inhibits oxidative stress and TNF-α secretion caused by exposure to high glucose in cultured U937 monocytes. Biochem. Biophys. Res. Commun. 289 (2001) 687-691
12. Kordella T. Chromium: can it help kids with type 2. Diabetes Forecast 57 (2004) 83-85
13. Anderson R.A. Essentiality of chromium in humans. Sci. Total Environ. 86 (1989) 75-81
14. Govindaraju K., Ramasami T., and Ramaswamy D. Chymotrypsin-catalyzed hydrolysis of chromium (III) derivatives of insulin: evidence for stabilization of the protein through interactions with metal ions. J. Inorg. Biochem. 35 (1989) 127-135
15. Govindaraju K., Ramasami T., and Ramaswamy D. Chromium (III)-insulin derivatives and their implication in glucose metabolism. J. Inorg. Biochem. 35 (1989) 137-147
16. Mertz W., and Schwarz K. Impaired intravenous glucose tolerance as an early sign of dietary necrotic liver degeneration. Arch. Biochem. Biophys. 58 (1955) 504-506
17. Schwarz K., and Mertz W. A glucose tolerance factor and its differentiation from factor 3. Arch. Biochem. Biophys. 72 (1957) 515-518
18. Schwarz K., and Mertz W. Chromium (III) and the glucose tolerance factor. Arch. Biochem. Biophys. 85 (1959) 292-295
19. Toepfer E.W., Mertz W., Polansky M.M., Roginski E.E., and Wolf W.R. Preparation of chromium-containing material of glucose tolerance factor activity from brewer's yeast extracts and by synthesis. J. Agric. Food Chem. 25 (1977) 162
20. Anderson R.A., and Mertz W. Glucose tolerance factor: an essential dietary agent. Trends Biochem. Sci. 2 (1977) 277-279
21. Davis C.M., and Vincent J.B. Isolation and characterization of a biologically active form of chromium oligopeptide from bovine liver. Arch. Biochem. Biophys. 339 (1997) 335-343
22. Dinakarpandian D., Morrissette V., Chaudhary S., Amini K., Bennett B., and Van Horn J.D. An informatics search for the low-molecular weight chromium-binding peptide. BMC Chem. Biol. 4 (2004) Art. No. 2
23. Jacquamet L., Sun Y., Hatfield J., Gu W., Cramer S.P., Crowder M.W., Lorigan G.A., Vincent J.B., and Latour J.M. Characterization of chromodulin by X-ray absorption and electron paramagnetic spectroscopies and magnetic susceptibility measurements. J. Am. Chem. Soc. 125 (2003) 774-780
24. Dodson G.G., Glusker J.P., Ramaseshan S., and Venkatesan K. The collected works of Dorothy Crowfoot Hodgkin. Insulin I (1994)
25. K.S. Bartles, C. Klein, 2003. Available from: .
26. Howell L., and Smith G.D. Identification of heavy-atom derivatives by normal probability methods. J. Appl. Cryst. 25 (1992) 81-86
27. Collaborative Computational Project, No. 4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D50 (1994) 760-763
28. Navaza J. AMoRe: an automated package for molecular replacement. Acta Crystallogr. A50 (1994) 157-163
29. Murshudov G.N., Vagin A.A., and Dodson E.J. Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr. D53 (1997) 240-255
30. Emsley P., and Cowtan K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D60 (2004) 2126-2132
31. Badger J., Li Y., and Caspar D.L.D. Thallium counterion distribution in cubic insulin crystals determined from anomalous x-ray diffraction data. Proc. Natl. Acad. Sci. USA 91 (1994) 1224-1228