Discovery of a Small Molecule Activator of the Human Ether-a- Go-Go-Related Gene (HERG) Cardiac K+ Channel
Kang J., Chen X.L., Wang H., et al. Discovery of a Small Molecule Activator of the Human Ether-a- Go-Go-Related Gene (HERG) Cardiac K+ Channel. Mol Pharmacol 67 (2005) 827-836
Mechanism of Action of a Novel Human Ether-a-Go-Go-Related Gene Channel Activator
Casis O., Olesen S.P., and Sanguinetti M.C. Mechanism of Action of a Novel Human Ether-a-Go-Go-Related Gene Channel Activator. Mol Pharmacol 69 (2006) 658-665
Biophysical Characterization of the New Human Ether-a-Go-Go-Related Gene Channel Opener NS3623 [N-(4-Bromo-2-(1H-Tetrazol-5-Yl)-Phenyl)-N'-(3'-Trifluoromethylphenyl)Urea]
Hansen R.S., Diness T.G., Christ T., et al. Biophysical Characterization of the New Human Ether-a-Go-Go-Related Gene Channel Opener NS3623 [N-(4-Bromo-2-(1H-Tetrazol-5-Yl)-Phenyl)-N'-(3'-Trifluoromethylphenyl)Urea]. Mol Pharmacol 70 (2006) 1319-1329
Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG
Wolpert C., Schimpf R., Giustetto C., et al. Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG. J Cardiovasc Electrophysiol 1 (2005) 54-58
Patel C, Antzelevitch C. Cellular Basis for Arrhythmogenesis in an Experimental Model of the SQT1 Form of the Short QT Syndrome. Heart Rhythm. In Press.
Patel C, Antzelevitch C. Cellular Basis for Arrhythmogenesis in an Experimental Model of the SQT1 Form of the Short QT Syndrome. Heart Rhythm. In Press.
10
14944383670
Activators of Cation Channels: Potential in Treatment of Channelopathies
Seebohm G. Activators of Cation Channels: Potential in Treatment of Channelopathies. Mol Pharmacol 67 (2005) 585-588