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Volumn 93, Issue 2, 2008, Pages 215-223

Multicenter study of ZAP-70 expression in patients with B-cell chronic lymphocytic leukemia using an optimized flow cytometry method

Author keywords

B cell chronic lymphocytic leukemia; CD38; Prognosis; ZAP 70

Indexed keywords

CD38 ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; PROTEIN KINASE ZAP 70;

EID: 40849105146     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: 10.3324/haematol.11622     Document Type: Article
Times cited : (34)

References (35)
  • 1
    • 79959302190 scopus 로고    scopus 로고
    • Dighiero G. CLL Biology and prognosis. Hematology Am Soc Hematol Educ Program 2005;278-84.
    • Dighiero G. CLL Biology and prognosis. Hematology Am Soc Hematol Educ Program 2005;278-84.
  • 3
    • 0019427092 scopus 로고
    • A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis
    • Binet JL, Auquier A, Dighiero G, Chastang C, Piguet H, Goasguen J, et al. A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer 1981;48:198-206.
    • (1981) Cancer , vol.48 , pp. 198-206
    • Binet, J.L.1    Auquier, A.2    Dighiero, G.3    Chastang, C.4    Piguet, H.5    Goasguen, J.6
  • 6
    • 0036281736 scopus 로고    scopus 로고
    • Prognosis in chronic lymphocytic leukemia: Let's have a look!
    • Montserrat E. Prognosis in chronic lymphocytic leukemia: let's have a look! Haematologica 2002;87:561-2.
    • (2002) Haematologica , vol.87 , pp. 561-562
    • Montserrat, E.1
  • 8
    • 0033567968 scopus 로고    scopus 로고
    • Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F, Ghiotto F, Valetto A, Allen SL, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999;94:1840-7.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3    Ghiotto, F.4    Valetto, A.5    Allen, S.L.6
  • 9
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999;94:1848-54.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 10
    • 0037103257 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in CLL: Clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors
    • Oscier DG, Gardiner AC, Mould SJ, Glide S, Davis ZA, Ibbotson RE, et al. Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors. Blood 2002;100:1177-84.
    • (2002) Blood , vol.100 , pp. 1177-1184
    • Oscier, D.G.1    Gardiner, A.C.2    Mould, S.J.3    Glide, S.4    Davis, Z.A.5    Ibbotson, R.E.6
  • 11
    • 0037103212 scopus 로고    scopus 로고
    • V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia
    • Krober A, Seiler T, Benner A, Bullinger L, Bruckle E, et al. V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia. Blood 2002;100:1410-6.
    • (2002) Blood , vol.100 , pp. 1410-1416
    • Krober, A.1    Seiler, T.2    Benner, A.3    Bullinger, L.4    Bruckle, E.5
  • 12
    • 0842285686 scopus 로고    scopus 로고
    • Prognosis at diagnosis: Integrating molecular biologic insights into clinical practice for patients with CLL
    • Shanafelt TD, Geyer SM, Kay NE. Prognosis at diagnosis: integrating molecular biologic insights into clinical practice for patients with CLL. Blood. 2004;103:1202-10.
    • (2004) Blood , vol.103 , pp. 1202-1210
    • Shanafelt, T.D.1    Geyer, S.M.2    Kay, N.E.3
  • 13
    • 15244342190 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia: Novel prognostic factors and their relevance for risk-adapted therapeutic strategies
    • Montillo M, Hamblin T, Hallek M, Montserrat E, Morra E. Chronic lymphocytic leukemia: novel prognostic factors and their relevance for risk-adapted therapeutic strategies. Haematologica 2005;90:391-9.
    • (2005) Haematologica , vol.90 , pp. 391-399
    • Montillo, M.1    Hamblin, T.2    Hallek, M.3    Montserrat, E.4    Morra, E.5
  • 14
    • 0035803371 scopus 로고    scopus 로고
    • Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
    • Rosenwald A, Alizadeh AA, Widhopf G, Simon R, Davis RE, Yu X, et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 2001;194:1639-47.
    • (2001) J Exp Med , vol.194 , pp. 1639-1647
    • Rosenwald, A.1    Alizadeh, A.A.2    Widhopf, G.3    Simon, R.4    Davis, R.E.5    Yu, X.6
  • 15
    • 0037406968 scopus 로고    scopus 로고
    • ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia
    • Crespo M, Bosch F, Villamor N, Bellosillo B, Colomer D, Rozman M, et al. ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. N Engl J Med 2003;348:1764-75.
    • (2003) N Engl J Med , vol.348 , pp. 1764-1775
    • Crespo, M.1    Bosch, F.2    Villamor, N.3    Bellosillo, B.4    Colomer, D.5    Rozman, M.6
  • 17
    • 4143105617 scopus 로고    scopus 로고
    • ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia
    • Rassenti LZ, Huynh L, Toy TL, Chen L, Keating MJ, Gribben JG, et al. ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N Engl J Med 2004; 351:893-901.
    • (2004) N Engl J Med , vol.351 , pp. 893-901
    • Rassenti, L.Z.1    Huynh, L.2    Toy, T.L.3    Chen, L.4    Keating, M.J.5    Gribben, J.G.6
  • 18
    • 14944352799 scopus 로고    scopus 로고
    • ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia
    • Chen L, Apgar J, Huynh L, Dicker F, Giago-McGahan T, Rassenti L, et al. ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia. Blood 2005;105:2036-41.
    • (2005) Blood , vol.105 , pp. 2036-2041
    • Chen, L.1    Apgar, J.2    Huynh, L.3    Dicker, F.4    Giago-McGahan, T.5    Rassenti, L.6
  • 20
    • 33748485377 scopus 로고    scopus 로고
    • Evaluation of ZAP-70 expression by flow cytometry in chronic lymphocytic leukemia: A multicentric international harmonization process
    • Letestu R, Rawstron A, Ghia P, Villamor N, Leuven NB, Boettcher S, et al. Evaluation of ZAP-70 expression by flow cytometry in chronic lymphocytic leukemia: a multicentric international harmonization process. Cytometry B Clin Cytom 2006;70:309-14.
    • (2006) Cytometry B Clin Cytom , vol.70 , pp. 309-314
    • Letestu, R.1    Rawstron, A.2    Ghia, P.3    Villamor, N.4    Leuven, N.B.5    Boettcher, S.6
  • 21
    • 33748502318 scopus 로고    scopus 로고
    • An optimized whole blood method for flow cytometric measurement of ZAP-70 protein expression in chronic lymphocytic leukemia
    • Shankey TV, Forman M, Scibelli P, Cobb J, Smith CM, Mills R, et al. An optimized whole blood method for flow cytometric measurement of ZAP-70 protein expression in chronic lymphocytic leukemia. Cytometry B Clin Cytom 2006;70:259-69.
    • (2006) Cytometry B Clin Cytom , vol.70 , pp. 259-269
    • Shankey, T.V.1    Forman, M.2    Scibelli, P.3    Cobb, J.4    Smith, C.M.5    Mills, R.6
  • 23
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936
    • van Dongen JJ, Langerak AW, Bruggemann M, Evans PA, Hummel M, Lavender FL, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003;17:2257-317.
    • (2003) Leukemia , vol.17 , pp. 2257-2317
    • van Dongen, J.J.1    Langerak, A.W.2    Bruggemann, M.3    Evans, P.A.4    Hummel, M.5    Lavender, F.L.6
  • 24
    • 33747588762 scopus 로고    scopus 로고
    • Mutated or non-mutated? Which database to choose when determining the IgVH hypermutation status in chronic lymphocytic leukemia?
    • Pekova S, Baran-Marszak F, Schwarz J, Matoska V. Mutated or non-mutated? Which database to choose when determining the IgVH hypermutation status in chronic lymphocytic leukemia? Haematologica 2006;91:ELT01.
    • (2006) Haematologica , vol.91
    • Pekova, S.1    Baran-Marszak, F.2    Schwarz, J.3    Matoska, V.4
  • 26
    • 0031000752 scopus 로고    scopus 로고
    • Mathematical tools for demonstrating the clinical usefulness of biochemical markers
    • Boyd JC. Mathematical tools for demonstrating the clinical usefulness of biochemical markers. Scand J Clin Lab Invest Suppl 1997;227:46-63.
    • (1997) Scand J Clin Lab Invest Suppl , vol.227 , pp. 46-63
    • Boyd, J.C.1
  • 27
    • 33748503730 scopus 로고    scopus 로고
    • ZAP-70 expression in B-cell chronic lymphocytic leukemia: Evaluation by external (isotypic) or internal (T/NK cells) controls and correlation with IgV(H) mutations
    • Zucchetto A, Bomben R, Bo MD, Nanni P, Bulian P, Rossi FM, et al. ZAP-70 expression in B-cell chronic lymphocytic leukemia: evaluation by external (isotypic) or internal (T/NK cells) controls and correlation with IgV(H) mutations. Cytometry B Clin Cytom 2006;70:284-92.
    • (2006) Cytometry B Clin Cytom , vol.70 , pp. 284-292
    • Zucchetto, A.1    Bomben, R.2    Bo, M.D.3    Nanni, P.4    Bulian, P.5    Rossi, F.M.6
  • 28
    • 0842276675 scopus 로고    scopus 로고
    • ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia
    • Durig J, Nuckel H, Cremer M, Fuhrer A, Halfmeyer K, Fandrey J, et al. ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia. Leukemia 2003;17:2426-34.
    • (2003) Leukemia , vol.17 , pp. 2426-2434
    • Durig, J.1    Nuckel, H.2    Cremer, M.3    Fuhrer, A.4    Halfmeyer, K.5    Fandrey, J.6
  • 29
    • 33644881106 scopus 로고    scopus 로고
    • Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia
    • Krober A, Bloehdorn J, Hafner S, Buhler A, Seiler T, Kienle D, et al. Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia. J Clin Oncol 2006;24:969-75.
    • (2006) J Clin Oncol , vol.24 , pp. 969-975
    • Krober, A.1    Bloehdorn, J.2    Hafner, S.3    Buhler, A.4    Seiler, T.5    Kienle, D.6
  • 30
    • 33747886670 scopus 로고    scopus 로고
    • Use of prognostic factors in risk stratification at diagnosis and time of treatment of patients with chronic lymphocytic leukemia
    • Gowda A, Byrd JC. Use of prognostic factors in risk stratification at diagnosis and time of treatment of patients with chronic lymphocytic leukemia. Curr Opin Hematol 2006;13:266-72.
    • (2006) Curr Opin Hematol , vol.13 , pp. 266-272
    • Gowda, A.1    Byrd, J.C.2
  • 31
    • 33646472451 scopus 로고    scopus 로고
    • ZAP-70 is expressed by normal and malignant human B-cell subsets of different maturational stage
    • Scielzo C, Camporeale A, Geuna M, Alessio M, Poggi A, Zocchi MR, et al. ZAP-70 is expressed by normal and malignant human B-cell subsets of different maturational stage. Leukemia 2006;20:689-95.
    • (2006) Leukemia , vol.20 , pp. 689-695
    • Scielzo, C.1    Camporeale, A.2    Geuna, M.3    Alessio, M.4    Poggi, A.5    Zocchi, M.R.6
  • 32
    • 0842276675 scopus 로고    scopus 로고
    • ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia
    • Durig J, Nuckel H, Cremer M, Fuhrer A, Halfmeyer K, Fandrey J, et al. ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia. Leukemia 2003;17:2426-34.
    • (2003) Leukemia , vol.17 , pp. 2426-2434
    • Durig, J.1    Nuckel, H.2    Cremer, M.3    Fuhrer, A.4    Halfmeyer, K.5    Fandrey, J.6
  • 33
    • 10744222814 scopus 로고    scopus 로고
    • ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile
    • Wiestner A, Rosenwald A, Barry TS, Wright G, Davis RE, Henrickson SE, et al. ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood 2003;101:4944-51.
    • (2003) Blood , vol.101 , pp. 4944-4951
    • Wiestner, A.1    Rosenwald, A.2    Barry, T.S.3    Wright, G.4    Davis, R.E.5    Henrickson, S.E.6
  • 34
    • 14944353438 scopus 로고    scopus 로고
    • Wiestner A. More ZAP for chronic lymphocytic leukemia (CLL). Blood 2005;105:1839-40.
    • Wiestner A. More ZAP for chronic lymphocytic leukemia (CLL). Blood 2005;105:1839-40.
  • 35
    • 33748484269 scopus 로고    scopus 로고
    • Discordant results of flow cytometric ZAP-70 expression status in B-CLL samples if different gating strategies are applied
    • Wilhelm C, Neubauer A, Brendel C. Discordant results of flow cytometric ZAP-70 expression status in B-CLL samples if different gating strategies are applied. Cytometry B Clin Cytom 2006;70:242-50.
    • (2006) Cytometry B Clin Cytom , vol.70 , pp. 242-250
    • Wilhelm, C.1    Neubauer, A.2    Brendel, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.