Determination of leukocyte DNA 6-thioguanine nucleotide levels by high-performance liquid chromatography with fluorescence detection

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 864, Issue 1-2, 2008, Pages 149-155

  Olesen, Karen Marie ^a   Hansen, Steen Honoré ^a   Sidenius, Ulrik ^b   Schmiegelow, Kjeld ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NOVOZYMES A S   (Denmark)

^c International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

Author keywords

6 Thioguanine nucleotide; Acute lymphoblastic leukaemia; Chloroacetaldehyde; DNA; Etheno adenine; High performance liquid chromatography; Immobilized metal ion affinity chromatography

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKAEMIA; CHLOROACETALDEHYDE; ETHENO ADENINES; IMMOBILIZED METAL ION AFFINITY CHROMATOGRAPHY; THIOGUANINE NUCLEOTIDE;

ALDEHYDES; DERIVATIVES; DISEASES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METAL IONS; NUCLEOTIDES;

DNA;

1,N 6 ETHENO ADENINE; ADENINE DERIVATIVE; CHLOROACETALDEHYDE; DNA; METAL ION; N 2,3 ETHENO 6 THIOGUANINE; N 2,3 ETHENO GUANINE; NUCLEOTIDE; TIOGUANINE; UNCLASSIFIED DRUG;

ACCURACY; AFFINITY CHROMATOGRAPHY; ARTICLE; BLOOD SAMPLING; COHORT ANALYSIS; CONTROLLED STUDY; DERIVATIZATION; DNA DETERMINATION; DNA EXTRACTION; DNA ISOLATION; FLUORESCENCE ANALYSIS; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; HYDROLYSIS; LEUKEMIA; LEUKOCYTE; NORMAL HUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CHILD; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; GUANINE NUCLEOTIDES; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; LEUKOCYTES; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THIOGUANINE; THIONUCLEOTIDES;

EID: 40849102457     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.02.007     Document Type: Article

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