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Volumn 63, Issue SUPPL. 87, 2008, Pages 5-28

Rupatadine in allergic rhinitis and chronic urticaria

Author keywords

Allergic rhinitis; Antiallergic antihistamines; Chronic urticaria; H 1 receptor antagonists; PAF receptor antagonists; Rupatadine

Indexed keywords

1 ACETYL 4 (8 CHLORO 5,6 DIHYDRO 11H BENZO[5,6]CYCLOHEPTA[1,2 B]PYRIDIN 11 YLIDENE)PIPERIDINE; APAFANT; CD11B ANTIGEN; CD18 ANTIGEN; CETIRIZINE; CHLORPHENIRAMINE; CLEMASTINE; DESLORATADINE; DIPHENHYDRAMINE; EBASTINE; FOROPAFANT; GINKGOLIDE B; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; HYDROXYZINE; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; KETOTIFEN; LEVOCABASTINE; LORATADINE; MEPYRAMINE; MIZOLASTINE; RUPATADINE; TERFENADINE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; THROMBOCYTE ACTIVATING FACTOR RECEPTOR AFFECTING AGENT; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 40749156700     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2008.01640.x     Document Type: Review
Times cited : (100)

References (94)
  • 3
    • 0029175839 scopus 로고
    • Allergic rhinitis an increasing clinical problem
    • Howarth PH, Holmberg K. Allergic rhinitis an increasing clinical problem. Allergy 1995 50 : 4 5.
    • (1995) Allergy , vol.50 , pp. 4-5
    • Howarth, P.H.1    Holmberg, K.2
  • 4
    • 0037136586 scopus 로고    scopus 로고
    • Eat dirt - The hygiene hypothesis and allergic diseases
    • Weiss ST. Eat dirt - the hygiene hypothesis and allergic diseases. New Engl J Med 2002 347 : 930 931.
    • (2002) New Engl J Med , vol.347 , pp. 930-931
    • Weiss, S.T.1
  • 5
    • 0004007672 scopus 로고    scopus 로고
    • AAAAI, Available at: (accessed January 2008).
    • AAAAI, The Allergy Report. Available at: http://www.theallergyreport.com (accessed January 2008).
    • The Allergy Report.
  • 6
    • 3142628329 scopus 로고    scopus 로고
    • Does rhinitis compromise night-time sleep and daytime productivity?
    • Meltzer EO. Does rhinitis compromise night-time sleep and daytime productivity? Clin Exp All Rev 2002 2 : 67 72.
    • (2002) Clin Exp All Rev , vol.2 , pp. 67-72
    • Meltzer, E.O.1
  • 7
    • 27244460644 scopus 로고    scopus 로고
    • Effectiveness and safety of new-generation antihistamines in allergenic rhinitis and urticaria
    • Potter PC. Effectiveness and safety of new-generation antihistamines in allergenic rhinitis and urticaria. SA Fam Pract 2005 47 : 24 28.
    • (2005) SA Fam Pract , vol.47 , pp. 24-28
    • Potter, P.C.1
  • 10
    • 0033963977 scopus 로고    scopus 로고
    • Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology
    • Van Cauwenberge P, Bachert C, Passalacqua G et al. Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology. Allergy 2000 55 : 116 134.
    • (2000) Allergy , vol.55 , pp. 116-134
    • Van Cauwenberge, P.1    Bachert, C.2    Passalacqua, G.3
  • 12
    • 24744459262 scopus 로고    scopus 로고
    • i antihistamines in the treatment of chronic idiopathic urticaria
    • i antihistamines in the treatment of chronic idiopathic urticaria. Cutis 2005 76 : 118 126.
    • (2005) Cutis , vol.76 , pp. 118-126
    • Monroe, E.1
  • 13
    • 0032932042 scopus 로고    scopus 로고
    • Targeted intervention programs: Creating a customized practice model to improve the treatment of allergic rhinitis in a managed care population
    • Gregory C, Cifaldi M, Tanner LA. Targeted intervention programs: creating a customized practice model to improve the treatment of allergic rhinitis in a managed care population. Am J Manag Care 1999 5 : 485 496.
    • (1999) Am J Manag Care , vol.5 , pp. 485-496
    • Gregory, C.1    Cifaldi, M.2    Tanner, L.A.3
  • 14
    • 8644252665 scopus 로고    scopus 로고
    • Prevalence and rate of diagnosis of allergic asthma in Europe
    • Bauchau V, Durham SR. Prevalence and rate of diagnosis of allergic asthma in Europe. Eur Respir J 2004 24 : 758 764.
    • (2004) Eur Respir J , vol.24 , pp. 758-764
    • Bauchau, V.1    Durham, S.R.2
  • 16
    • 33646495721 scopus 로고    scopus 로고
    • Inflammatory patterns in allergic rhinitis
    • Foley S, Hamid Q. Inflammatory patterns in allergic rhinitis. Clin Exp Allergy Rev 2006 6 : 91 95.
    • (2006) Clin Exp Allergy Rev , vol.6 , pp. 91-95
    • Foley, S.1    Hamid, Q.2
  • 17
    • 0034912161 scopus 로고    scopus 로고
    • Allergic rhinitis: Definition, epidemiology, pathophysiology, detection, and diagnosis
    • Skoner DP. Allergic rhinitis: definition, epidemiology, pathophysiology, detection, and diagnosis. J Allergy Clin Immunol 2001 108 (Suppl. B S2 S8.
    • (2001) J Allergy Clin Immunol , vol.108
    • Skoner, D.P.1
  • 18
    • 0031042526 scopus 로고    scopus 로고
    • Overview of comorbid associations of allergic rhinitis
    • Spector SL. Overview of comorbid associations of allergic rhinitis. J Allergy Clin Immunol 1997 99 (Suppl. S773 S780.
    • (1997) J Allergy Clin Immunol , vol.99
    • Spector, S.L.1
  • 19
    • 0031047374 scopus 로고    scopus 로고
    • One airway, one disease
    • Grossmann J. One airway, one disease. Chest 1997 111 (Suppl. 2 11S 16S.
    • (1997) Chest , vol.111 , Issue.2
    • Grossmann, J.1
  • 22
    • 34247370280 scopus 로고    scopus 로고
    • Towards rationalizing the nomenclature and classification of urticaria: Some guidance on guidelines
    • Grattan CEH. Towards rationalizing the nomenclature and classification of urticaria: some guidance on guidelines. Clin Exp Allergy 2007 37 : 625 626.
    • (2007) Clin Exp Allergy , vol.37 , pp. 625-626
    • Grattan, C.E.H.1
  • 25
    • 9744281159 scopus 로고    scopus 로고
    • Chronic urticaria: Aetiology, management and current and future treatment options
    • Kozel MM, Sabroe RA. Chronic urticaria: aetiology, management and current and future treatment options. Drugs 2004 64 : 2515 2536.
    • (2004) Drugs , vol.64 , pp. 2515-2536
    • Kozel, M.M.1    Sabroe, R.A.2
  • 26
    • 33947317266 scopus 로고    scopus 로고
    • Rupatadine fumarate: Antiallergic, histamine and PAF antagonist
    • Garcia-Rafanell J. Rupatadine fumarate: antiallergic, histamine and PAF antagonist. Drugs Fut 1996 21 : 1033 1036.
    • (1996) Drugs Fut , vol.21 , pp. 1033-1036
    • Garcia-Rafanell, J.1
  • 28
    • 0041431065 scopus 로고    scopus 로고
    • I receptor and platelet-activating factor (PAF) antagonist: A review of pharmacological profile and clinical management of allergic rhinitis
    • I receptor and platelet-activating factor (PAF) antagonist: a review of pharmacological profile and clinical management of allergic rhinitis. Drugs Today (Barc) 2003 39 : 451 468.
    • (2003) Drugs Today (Barc) , vol.39 , pp. 451-468
    • Izquierdo, I.1    Merlos, M.2    Garcia-Rafanell, J.3
  • 29
    • 33749353525 scopus 로고    scopus 로고
    • Rupatadine: Pharmacological profile and its use in the treatment of allergic disorders
    • Picado C. Rupatadine: pharmacological profile and its use in the treatment of allergic disorders. Expert Opin Pharmacother 2006 7 : 1989 2001.
    • (2006) Expert Opin Pharmacother , vol.7 , pp. 1989-2001
    • Picado, C.1
  • 30
    • 33947310075 scopus 로고    scopus 로고
    • Rupatadine: A review of its use in the management of allergic disorders
    • Keam SJ, Plosker GL. Rupatadine: a review of its use in the management of allergic disorders. Drugs 2007 67 : 457 474.
    • (2007) Drugs , vol.67 , pp. 457-474
    • Keam, S.J.1    Plosker, G.L.2
  • 31
    • 0034500798 scopus 로고    scopus 로고
    • Allergic rhinitis: Not purely a histamine-related disease
    • Howarth PH, Salagean M, Dokic D. Allergic rhinitis: not purely a histamine-related disease. Allergy 2000 55 : 7 16.
    • (2000) Allergy , vol.55 , pp. 7-16
    • Howarth, P.H.1    Salagean, M.2    Dokic, D.3
  • 32
    • 3142707567 scopus 로고    scopus 로고
    • Inflammatory responses in allergic rhinitis: Traditional approaches and novel treatment strategies
    • Quraishi SA, Davies MJ, Craig TJ. Inflammatory responses in allergic rhinitis: traditional approaches and novel treatment strategies. J Am Osteopathol Assoc 2004 104 (Suppl. 5 S7 S15.
    • (2004) J Am Osteopathol Assoc , vol.104 , Issue.5
    • Quraishi, S.A.1    Davies, M.J.2    Craig, T.J.3
  • 33
    • 0033501912 scopus 로고    scopus 로고
    • Pathophysiology of the inflammatory response
    • Pearlman DS. Pathophysiology of the inflammatory response. J Allergy Clin Immunol 1999 104 : S132 S137.
    • (1999) J Allergy Clin Immunol , vol.104
    • Pearlman, D.S.1
  • 34
    • 0024436975 scopus 로고
    • Major basic protein and eosinophils-derived neurotoxin concentrations in nasal-lavage fluid after antigen challenge: Effect of systemic corticosteroids and relationship to eosinophil influx
    • Bascom R, Pipkorn U, Proud D, Dunette S, Gleich GJ, Lichtenstein LM et al. Major basic protein and eosinophils-derived neurotoxin concentrations in nasal-lavage fluid after antigen challenge: effect of systemic corticosteroids and relationship to eosinophil influx. J Allergy Clin Immunol 1989 84 : 338 346.
    • (1989) J Allergy Clin Immunol , vol.84 , pp. 338-346
    • Bascom, R.1    Pipkorn, U.2    Proud, D.3    Dunette, S.4    Gleich, G.J.5    Lichtenstein, L.M.6
  • 35
    • 0023708102 scopus 로고
    • The influx of inflammatory cells into nasal washings during the late-phase response to antigen challenge. Effect of systemic steroid pretreatment
    • Bascom R, Pipkorn U, Lichtenstein LM, Naclerio RM. The influx of inflammatory cells into nasal washings during the late-phase response to antigen challenge. Effect of systemic steroid pretreatment. Am Rev Respir Dis 1988 138 : 406 412.
    • (1988) Am Rev Respir Dis , vol.138 , pp. 406-412
    • Bascom, R.1    Pipkorn, U.2    Lichtenstein, L.M.3    Naclerio, R.M.4
  • 36
    • 0034517226 scopus 로고    scopus 로고
    • Clinical advantages of dual activity in allergic rhinitis
    • Horak F. Clinical advantages of dual activity in allergic rhinitis. Allergy 2000 55 (Suppl. 64 34 39.
    • (2000) Allergy , vol.55 , Issue.64 , pp. 34-39
    • Horak, F.1
  • 37
    • 0030899302 scopus 로고    scopus 로고
    • Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF)
    • Merlos M, Giral M, Balsa D, Ferrando R, Queralt M, Puigdemont A et al. Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF). J Pharmacol Exp Ther 1997 280 : 114 121.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 114-121
    • Merlos, M.1    Giral, M.2    Balsa, D.3    Ferrando, R.4    Queralt, M.5    Puigdemont, A.6
  • 38
    • 33749324317 scopus 로고    scopus 로고
    • Inhibitory activity of rupatadine on pro-inflammatory cytokine production, relationship with binding affinity
    • Barrón S, Ramis I, Garcia-Rafanell J, Merlos M. Inhibitory activity of rupatadine on pro-inflammatory cytokine production, relationship with binding affinity. Methods Find Exp Clin Pharmacol 2005 27 (Suppl. 2 161 162.
    • (2005) Methods Find Exp Clin Pharmacol , vol.27 , Issue.2 , pp. 161-162
    • Barrón, S.1    Ramis, I.2    Garcia-Rafanell, J.3    Merlos, M.4
  • 39
    • 33947331730 scopus 로고    scopus 로고
    • CNS activity profile of rupatadine fumarate, a new dual receptor antagonist of platelet-activating factor (PAF) and histamine
    • Giral M, Balsa D, Ferrando R, Merlos M, Garcia-Rafanell J, Forn J. CNS activity profile of rupatadine fumarate, a new dual receptor antagonist of platelet-activating factor (PAF) and histamine. Allergy 1998 53 (Suppl. 131.
    • (1998) Allergy , vol.53 , pp. 131
    • Giral, M.1    Balsa, D.2    Ferrando, R.3    Merlos, M.4    Garcia-Rafanell, J.5    Forn, J.6
  • 41
    • 4244059394 scopus 로고    scopus 로고
    • Effect of topical rupatadine in experimental conjunctivitis in guinea pigs: Macroscopic evaluation of ocular lesions
    • Merlos M, Ferrando R, Giral M, Ramis I, Forn J. Effect of topical rupatadine in experimental conjunctivitis in guinea pigs: macroscopic evaluation of ocular lesions. J Allergy Clin lmmunol 2001 107 (Suppl. 2 S310.
    • (2001) J Allergy Clin Lmmunol , vol.107 , Issue.2
    • Merlos, M.1    Ferrando, R.2    Giral, M.3    Ramis, I.4    Forn, J.5
  • 42
    • 0030497903 scopus 로고    scopus 로고
    • Dual effect of a new compound, rupatadine, on edema induced by platelet-activating factor and histamine in dogs: Comparison with antihistamines and PAF antagonists
    • Queralt M, Merlos M, Giral M, Puigdemont A. Dual effect of a new compound, rupatadine, on edema induced by platelet-activating factor and histamine in dogs: comparison with antihistamines and PAF antagonists. Drug Dev Res 1996 39 : 12 18.
    • (1996) Drug Dev Res , vol.39 , pp. 12-18
    • Queralt, M.1    Merlos, M.2    Giral, M.3    Puigdemont, A.4
  • 43
    • 0031691907 scopus 로고    scopus 로고
    • Lnhibitory effects of rupatadine on mast cell histamine release and skin wheal development induced by Ascaris suum in hypersensitive dogs
    • Queralt M, Brazis P, Merlos M, Puigdemont A. lnhibitory effects of rupatadine on mast cell histamine release and skin wheal development induced by Ascaris suum in hypersensitive dogs. Drug Dev Res 1998 44 : 49 55.
    • (1998) Drug Dev Res , vol.44 , pp. 49-55
    • Queralt, M.1    Brazis, P.2    Merlos, M.3    Puigdemont, A.4
  • 44
    • 0034221301 scopus 로고    scopus 로고
    • In vitro inhibitory effect of rupatadine on histamine and TNF-α release from dispersed canine skin mast cells and the human mast cell line HMC-I
    • Queralt M, Brazís P, Merlos M, de Mora F, Puigdemont A. In vitro inhibitory effect of rupatadine on histamine and TNF-α release from dispersed canine skin mast cells and the human mast cell line HMC-I. lnflamm Res 2000 49 : 355 360.
    • (2000) Lnflamm Res , vol.49 , pp. 355-360
    • Queralt, M.1    Brazís, P.2    Merlos, M.3    De Mora, F.4    Puigdemont, A.5
  • 46
    • 31444441794 scopus 로고    scopus 로고
    • Effects of rupatadine vs placebo on allergen-induced symptoms in patients exposed to aeroallergens in the Vienna Challenge Chamber
    • Stuebner P, Horak F, Zieglmayer R, Arnáiz E, Leuratti C, Peréz I et al. Effects of rupatadine vs placebo on allergen-induced symptoms in patients exposed to aeroallergens in the Vienna Challenge Chamber. Ann Allergy Asthma Immunol 2006 96 : 37 44.
    • (2006) Ann Allergy Asthma Immunol , vol.96 , pp. 37-44
    • Stuebner, P.1    Horak, F.2    Zieglmayer, R.3    Arnáiz, E.4    Leuratti, C.5    Peréz, I.6
  • 48
    • 8344261734 scopus 로고    scopus 로고
    • Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers
    • Barbanoj MJ, García-Gea C, Morte A, Izquierdo I, Pérez I, Jané F. Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers. Neuropsychobiology 2004 50 : 311 321.
    • (2004) Neuropsychobiology , vol.50 , pp. 311-321
    • Barbanoj, M.J.1    García-Gea, C.2    Morte, A.3    Izquierdo, I.4    Pérez, I.5    Jané, F.6
  • 49
    • 0031834441 scopus 로고    scopus 로고
    • Current status of platelet-activating factor antagonists
    • Curtin ML. Current status of platelet-activating factor antagonists. Exp Opin Ther Patents 1998 8 : 703 711.
    • (1998) Exp Opin Ther Patents , vol.8 , pp. 703-711
    • Curtin, M.L.1
  • 50
    • 0036182196 scopus 로고    scopus 로고
    • The platelet-activating factor receptor activates the extracellular signal-regulated kinase mitogen-activated protein kinase and induces proliferation of epidermal cells through an epidermal growth factor-receptor-dependent pathway
    • Marques SA, Dy LC, Southall MD, Yi Q, Smietana E, Kapur R et al. The platelet-activating factor receptor activates the extracellular signal-regulated kinase mitogen-activated protein kinase and induces proliferation of epidermal cells through an epidermal growth factor-receptor-dependent pathway. J Pharmacol Exp Ther 2002 300 : 1026 1035.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 1026-1035
    • Marques, S.A.1    Dy, L.C.2    Southall, M.D.3    Yi, Q.4    Smietana, E.5    Kapur, R.6
  • 51
    • 4243655510 scopus 로고    scopus 로고
    • Inhibitory effect of rupatadine on TNF-α release from human monocytes and mast cell line HMC-1
    • Merlos M, Ramis I, Balsa D, Queralt M, Brazis P, Pugidemont A. Inhibitory effect of rupatadine on TNF-α release from human monocytes and mast cell line HMC-1. J Allergy Clin lmmunol 2000 105 (Suppl. 1 S62.
    • (2000) J Allergy Clin Lmmunol , vol.105 , Issue.1
    • Merlos, M.1    Ramis, I.2    Balsa, D.3    Queralt, M.4    Brazis, P.5    Pugidemont, A.6
  • 54
    • 40749143011 scopus 로고    scopus 로고
    • Inhibition of PAF- and LTB4-induced human neutrophil chemotaxis by rupatadine using a new fluorescent chemotaxis assay
    • Ramis I, Giral M, Ferrando R, Merlos M. Inhibition of PAF- and LTB4-induced human neutrophil chemotaxis by rupatadine using a new fluorescent chemotaxis assay. Allergy 2000 55 (Suppl. 63 94 95.
    • (2000) Allergy , vol.55 , Issue.63 , pp. 94-95
    • Ramis, I.1    Giral, M.2    Ferrando, R.3    Merlos, M.4
  • 55
    • 40749099680 scopus 로고    scopus 로고
    • Rupatadine inhibits cytokine production and NF-κB activity by histamine H1 receptor-dependent mechanism
    • Barrón S, Roman J, Michelena P, Ramis I, Merlos M. Rupatadine inhibits cytokine production and NF-κB activity by histamine H1 receptor-dependent mechanism. Rev Rinol 2006 6 : 18.
    • (2006) Rev Rinol , vol.6 , pp. 18
    • Barrón, S.1    Roman, J.2    Michelena, P.3    Ramis, I.4    Merlos, M.5
  • 56
    • 33749334538 scopus 로고    scopus 로고
    • Effect of rupatadine on lymphocyte cytokine production
    • Barrón S, Ramis I, Merlos M. Effect of rupatadine on lymphocyte cytokine production. Allergy Clin Immunol Int 2005 1 (Suppl. 1 427.
    • (2005) Allergy Clin Immunol Int , vol.1 , Issue.1 , pp. 427
    • Barrón, S.1    Ramis, I.2    Merlos, M.3
  • 58
    • 33749338850 scopus 로고    scopus 로고
    • Effects of rupatadine on inflammatory mediators and transcription factors: A comparison with desloratadine and levocetirizine
    • Roumestan C, Henriquet C, Mathieu M, Bousquet J. Effects of rupatadine on inflammatory mediators and transcription factors: a comparison with desloratadine and levocetirizine Allergy Clin Immunol Int 2005 Suppl. 1 450.
    • (2005) Allergy Clin Immunol Int , Issue.1 , pp. 450
    • Roumestan, C.1    Henriquet, C.2    Mathieu, M.3    Bousquet, J.4
  • 59
    • 40749132833 scopus 로고    scopus 로고
    • Rupatadine fumarate is effective in the treatment of persistent allergic rhinitis: A multicentre study
    • Mion O, Mello Jr. J, Castro F, Cruz A, Mocelin M, Bogart P et al. Rupatadine fumarate is effective in the treatment of persistent allergic rhinitis: a multicentre study. Allergy 2007 62 (Suppl. 83 137.
    • (2007) Allergy , vol.62 , Issue.83 , pp. 137
    • Mion, O.1    Mellojr., J.2    Castro, F.3    Cruz, A.4    Mocelin, M.5    Bogart, P.6
  • 60
    • 0042254278 scopus 로고    scopus 로고
    • A dose ranging study of rupatadine fumarate in patients with seasonal allergic rhinitis
    • Izquierdo I, Paredes I, Lurigados C, Sospedra E, Cooper M, Thomas H. A dose ranging study of rupatadine fumarate in patients with seasonal allergic rhinitis. Allergy 2000 55 (Suppl. 63 275.
    • (2000) Allergy , vol.55 , Issue.63 , pp. 275
    • Izquierdo, I.1    Paredes, I.2    Lurigados, C.3    Sospedra, E.4    Cooper, M.5    Thomas, H.6
  • 61
    • 0043256677 scopus 로고    scopus 로고
    • Rupatadine in allergic rhinitis: Pooled analysis of efficacy data
    • Pérez I, De la Cruz G, Villa M, Izquierdo I. Rupatadine in allergic rhinitis: pooled analysis of efficacy data. Allergy 2002 57 (Suppl. 73 245.
    • (2002) Allergy , vol.57 , Issue.73 , pp. 245
    • Pérez, I.1    De La Cruz, G.2    Villa, M.3    Izquierdo, I.4
  • 65
    • 40749127894 scopus 로고    scopus 로고
    • Rupatadine reduces nasal obstruction in allergen-induced rhinitis
    • Valero A, Bartra J, Serrano C, Donado E, Garcia O, Izquierdo I et al. Rupatadine reduces nasal obstruction in allergen-induced rhinitis. Allergy 2007 62 (Suppl. 83 137 138.
    • (2007) Allergy , vol.62 , Issue.83 , pp. 137-138
    • Valero, A.1    Bartra, J.2    Serrano, C.3    Donado, E.4    Garcia, O.5    Izquierdo, I.6
  • 67
    • 45149093862 scopus 로고    scopus 로고
    • A 12-week placebo-controlled study of rupatadine 10 mg once daily comparative with cetirizine 10 mg once daily, in the treatment of persistent allergic rhinitis
    • In press
    • Fantin S, Maspero J, Bisbal C, Agache I, Donado E, Garcia O et al. A 12-week placebo-controlled study of rupatadine 10 mg once daily comparative with cetirizine 10 mg once daily, in the treatment of persistent allergic rhinitis. In press, Allergy, 2008.
    • (2008) Allergy
    • Fantin, S.1    Maspero, J.2    Bisbal, C.3    Agache, I.4    Donado, E.5    Garcia, O.6
  • 68
    • 34247212709 scopus 로고    scopus 로고
    • Rupatadine in the treatment of chronic idiopathic urticaria: A double-blind, randomized, placebo-controlled multicenter study
    • Gimenez-Arnau A, Pujol RM, Ianosi S, Kaszuba A, Malbran A, Poop G et al. Rupatadine in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled multicenter study. Allergy 2007 62 : 539 546.
    • (2007) Allergy , vol.62 , pp. 539-546
    • Gimenez-Arnau, A.1    Pujol, R.M.2    Ianosi, S.3    Kaszuba, A.4    Malbran, A.5    Poop, G.6
  • 69
    • 34247261896 scopus 로고    scopus 로고
    • Once-daily rupatadine improves the symptoms of chronic idiopathic urticaria: A randomised, double-blind, placebo-controlled study
    • Dubertret L, Zalupca L, Cristodoulo T, Benea V, Medina I, Fantin S et al. Once-daily rupatadine improves the symptoms of chronic idiopathic urticaria: a randomised, double-blind, placebo-controlled study. Eur J Dermatol 2007 17 : 223 228.
    • (2007) Eur J Dermatol , vol.17 , pp. 223-228
    • Dubertret, L.1    Zalupca, L.2    Cristodoulo, T.3    Benea, V.4    Medina, I.5    Fantin, S.6
  • 70
    • 40749115050 scopus 로고    scopus 로고
    • Fast onset of action of rupatadine in the reduction of pruritus in patients suffering from chronic urticaria: Pooled analysis
    • Gimenez-Arnau A, Donado E, Arnaiz E, Perez I, Izquierdo I. Fast onset of action of rupatadine in the reduction of pruritus in patients suffering from chronic urticaria: pooled analysis. Allergy 2007 62 (Suppl. 83 306.
    • (2007) Allergy , vol.62 , Issue.83 , pp. 306
    • Gimenez-Arnau, A.1    Donado, E.2    Arnaiz, E.3    Perez, I.4    Izquierdo, I.5
  • 72
    • 0142091793 scopus 로고    scopus 로고
    • Can quality of life be quantified?
    • Juniper EF. Can quality of life be quantified? Clin Exp All Rev 2002 2 : 57 60.
    • (2002) Clin Exp All Rev , vol.2 , pp. 57-60
    • Juniper, E.F.1
  • 73
    • 33749348014 scopus 로고    scopus 로고
    • Pharmacokinetic and safety profile of rupatadine when coadministered with azithromycin: A randomized, crossover, multiple-dose open study
    • Solans A, Merlos M, Antonijoan R, Barbanoj M, Donado E, Izquierdo I et al. Pharmacokinetic and safety profile of rupatadine when coadministered with azithromycin: a randomized, crossover, multiple-dose open study. Allergy Clin Immunol Int 2005 Suppl. 1 159.
    • (2005) Allergy Clin Immunol Int , Issue.1 , pp. 159
    • Solans, A.1    Merlos, M.2    Antonijoan, R.3    Barbanoj, M.4    Donado, E.5    Izquierdo, I.6
  • 74
    • 34547652652 scopus 로고    scopus 로고
    • Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: A single-dose, randomized, open-label, two-way crossover study
    • Solans A, Carbó M, Peña J, Nadal T, Izquierdo I, Merlos M. Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: a single-dose, randomized, open-label, two-way crossover study. Clin Therap 2007 29 : 900 908.
    • (2007) Clin Therap , vol.29 , pp. 900-908
    • Solans, A.1    Carbó, M.2    Peña, J.3    Nadal, T.4    Izquierdo, I.5    Merlos, M.6
  • 75
    • 32044435121 scopus 로고    scopus 로고
    • Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers
    • Barbanoj MJ, García-Gea C, Antonijoan R et al. Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers. Hum Psychopharmacol Clin Exp 2006 21 : 13 26.
    • (2006) Hum Psychopharmacol Clin Exp , vol.21 , pp. 13-26
    • Barbanoj, M.J.1    García-Gea, C.2    Antonijoan, R.3
  • 80
    • 33751160132 scopus 로고    scopus 로고
    • The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes
    • Hove-Madsen L, Llach A, Molina CE, Prat-Vidal C, Farré J, Roura S et al. The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes. Eur J Pharmacol 2006 553 : 215 221.
    • (2006) Eur J Pharmacol , vol.553 , pp. 215-221
    • Hove-Madsen, L.1    Llach, A.2    Molina, C.E.3    Prat-Vidal, C.4    Farré, J.5    Roura, S.6
  • 83
    • 33947313184 scopus 로고    scopus 로고
    • Lack of electrocardiographic effects of rupatadine, new nonsedating selective histamine H1-receptor and PAF antagonist
    • Izquierdo I, Pérez I, Villa M, Giral M, Merlos M, Forn J. Lack of electrocardiographic effects of rupatadine, new nonsedating selective histamine H1-receptor and PAF antagonist. Allergy 2001 56 (Suppl. 68 212.
    • (2001) Allergy , vol.56 , Issue.68 , pp. 212
    • Izquierdo, I.1    Pérez, I.2    Villa, M.3    Giral, M.4    Merlos, M.5    Forn, J.6
  • 84
    • 25044470433 scopus 로고    scopus 로고
    • Effects of rupatadine on cardiovascular profile in rats and guinea pigs: Comparison with other nonsedating antihistamines
    • Giral M, Merlos M, Balsa D, Ferrando R, Garcia-Rafanell J, Forn J. Effects of rupatadine on cardiovascular profile in rats and guinea pigs: comparison with other nonsedating antihistamines. Allergy 1997 52 (Suppl. 37 44 45.
    • (1997) Allergy , vol.52 , Issue.37 , pp. 44-45
    • Giral, M.1    Merlos, M.2    Balsa, D.3    Ferrando, R.4    Garcia-Rafanell, J.5    Forn, J.6
  • 85
    • 0043256675 scopus 로고    scopus 로고
    • Lack of cardiotoxic effects of rupatadine in isolated Purkinje fibres and its relationship with rupatadine cardiac levels
    • Ramis I, Giral M, Nieto C, Martel E, Merlos M. Lack of cardiotoxic effects of rupatadine in isolated Purkinje fibres and its relationship with rupatadine cardiac levels. Allergy 2000 55 (Suppl. 63 264.
    • (2000) Allergy , vol.55 , Issue.63 , pp. 264
    • Ramis, I.1    Giral, M.2    Nieto, C.3    Martel, E.4    Merlos, M.5
  • 86
    • 0032714434 scopus 로고    scopus 로고
    • Effects of rupatadine, a new dual antagonist of histamine and platelet-activating factor receptors, on human cardiac Kv1.5 channels
    • Caballero R, Valenzuela C, Longobardo M, Tamargo J, Delpón E. Effects of rupatadine, a new dual antagonist of histamine and platelet-activating factor receptors, on human cardiac Kv1.5 channels. Br J Pharmacol 1999 128 : 1071 1081.
    • (1999) Br J Pharmacol , vol.128 , pp. 1071-1081
    • Caballero, R.1    Valenzuela, C.2    Longobardo, M.3    Tamargo, J.4    Delpón, E.5
  • 87
  • 88
    • 34547547875 scopus 로고    scopus 로고
    • Lack of effects between rupatadine 10 mg and placebo on actual driving performance of healthy volunteers
    • Vuurman E, Theunissen E, van Oers A, van Leeuwen C, Jolles J. Lack of effects between rupatadine 10 mg and placebo on actual driving performance of healthy volunteers. Human Psychopharmacol Clin Exp 2007 22 : 289 297.
    • (2007) Human Psychopharmacol Clin Exp , vol.22 , pp. 289-297
    • Vuurman, E.1    Theunissen, E.2    Van Oers, A.3    Van Leeuwen, C.4    Jolles, J.5
  • 89
    • 22844433343 scopus 로고    scopus 로고
    • Is the impairment of quality of life acceptable for the patient?
    • Bousquet J. Is the impairment of quality of life acceptable for the patient? Clin Exp All Rev 2002 2 : 61 65.
    • (2002) Clin Exp All Rev , vol.2 , pp. 61-65
    • Bousquet, J.1
  • 90
    • 28244463512 scopus 로고    scopus 로고
    • Quality of life: Improvement due to treatment
    • Bachert C. Quality of life: improvement due to treatment. Clin Exp All Rev 2002 2 : 73 78.
    • (2002) Clin Exp All Rev , vol.2 , pp. 73-78
    • Bachert, C.1
  • 91
    • 0028332995 scopus 로고
    • Dermatology Life Quality lndex (DLQI): A simple practical measure for routine clinical use
    • Finlay AY, Khan GK. Dermatology Life Quality lndex (DLQI): a simple practical measure for routine clinical use. Clin Exp Dermatol 1994 9 : 210 216.
    • (1994) Clin Exp Dermatol , vol.9 , pp. 210-216
    • Finlay, A.Y.1    Khan, G.K.2
  • 92
    • 22844436333 scopus 로고    scopus 로고
    • Pharmacological profile of the new antihistamines
    • Tillement J-P. Pharmacological profile of the new antihistamines. Clin Exp All Rev 2005 5 : 7 11.
    • (2005) Clin Exp All Rev , vol.5 , pp. 7-11
    • Tillement, J.-P.1
  • 93
    • 22844433195 scopus 로고    scopus 로고
    • Anti-inflammatory properties of antihistamines: An update
    • Walsh GM. Anti-inflammatory properties of antihistamines: an update. Clin Exp All Rev 2005 5 : 21 25.
    • (2005) Clin Exp All Rev , vol.5 , pp. 21-25
    • Walsh, G.M.1
  • 94
    • 33645032466 scopus 로고    scopus 로고
    • Comparing the new antihistamines: The role of pharmacological parameters
    • Devillier P. Comparing the new antihistamines: the role of pharmacological parameters. Clin Exp Allergy 2006 36 : 5 7.
    • (2006) Clin Exp Allergy , vol.36 , pp. 5-7
    • Devillier, P.1


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