Prenatal treatment with retinoic acid promotes pulmonary alveologenesis in the nitrofen model of congenital diaphragmatic hernia

Journal of Pediatric Surgery

Volumn 43, Issue 3, 2008, Pages 500-507

  Montedonico, Sandra ^a,c   Sugimoto, Kaoru ^a   Felle, Patrick ^b   Bannigan, John ^b   Puri, Prem ^a  

^a OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSIDAD DE VALPARAÍSO   (Chile)

Author keywords

Congenital diaphragmatic hernia; Nitrofen; Pulmonary hypoplasia; Retinoic acid

Indexed keywords

NITROFEN; OLIVE OIL; RETINOIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONGENITAL DIAPHRAGM HERNIA; CONTROLLED STUDY; DNA CONTENT; FEMALE; FETUS; GAS EXCHANGE; GESTATION PERIOD; HYPOTHESIS; LUNG ALVEOLUS; LUNG DEVELOPMENT; LUNG HYPOPLASIA; LUNG VOLUME; LUNG WEIGHT; NONHUMAN; PRENATAL CARE; PRIORITY JOURNAL; PULMONARY ALVEOLOGENESIS; RAT; SPECTROPHOTOMETER; STEREOMETRY; TISSUE FIXATION; TOTAL LUNG CAPACITY;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; FETAL ORGAN MATURITY; HERNIA, DIAPHRAGMATIC; INJECTIONS, INTRAPERITONEAL; LUNG; PHENYL ETHERS; PREGNANCY; PREGNANCY, ANIMAL; PRENATAL CARE; PROBABILITY; PULMONARY ALVEOLI; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; RESPIRATORY SYSTEM ABNORMALITIES; SENSITIVITY AND SPECIFICITY; TRETINOIN;

EID: 40749147663     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2007.10.030     Document Type: Article

References (52)

1. Stege G., Fenton A., and Jaffray B. Nihilism in the 1990s: the true mortality of congenital diaphragmatic hernia. Pediatrics 112 (2003) 532-535
2. Ivascu F.A., and Hirschl R.B. New approaches to managing congenital diaphragmatic hernia. Semin Perinatol 28 (2004) 185-198
3. Doyle N.M., and Lally K.P. The CDH Study Group and advances in the clinical care of the patient with congenital diaphragmatic hernia. Semin Perinatol 28 (2004) 174-184
4. Harrison M.R., Adzick N.S., Bullard K.M., et al. Correction of congenital diaphragmatic hernia in utero VII: a prospective trial. J Pediatr Surg 32 (1997) 1637-1642
5. Harrison M.R., Keller R.L., Hawgood S.B., et al. A randomized trial of fetal endoscopic tracheal occlusion for severe fetal congenital diaphragmatic hernia. N Engl J Med 349 (2003) 1916-1924
6. Lally K.P., Bagolan P., Hosie S., et al. Corticosteroids for fetuses with congenital diaphragmatic hernia: can we show benefit?. J Pediatr Surg 41 (2006) 668-674
7. Zile M.H. Function of vitamin A in vertebrate embryonic development. J Nutr 131 (2001) 705-708
8. Ross S.A., McCaffery P.J., Drager U.C., et al. Retinoids in embryonal development. Physiol Rev 80 (2000) 1021-1054
9. Maden M. Retinoids in lung development and regeneration. Curr Top Dev Biol 61 (2004) 153-189
10. Desai T.J., Malpel S., Flentke G.R., et al. Retinoic acid selectively regulates Fgf10 expression and maintains cell identity in the prospective lung field of the developing foregut. Dev Biol 273 (2004) 402-415
11. Malpel S., Mendelsohn C., Cardoso W.V., et al. Regulation of retinoic acid signaling during lung morphogenesis. Development 127 (2000) 3057-3067
12. Nabeyrat E., Besnard V., Corroyer S., et al. Retinoic acid-induced proliferation of lung alveolar epithelial cells: relation with the IGF system. Am J Physiol 275 (1998) L71-L79
13. Massaro G.D., and Massaro D. Postnatal treatment with retinoic acid increases the number of pulmonary alveoli in rats. Am J Physiol 270 (1996) L305-L310
14. Hind M., and Maden M. Retinoic acid induces alveolar regeneration in the adult mouse lung. Eur Respir J 23 (2004) 20-27
15. Wilson J.G., Roth C.B., and Warkany J. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am J Anat 92 (1953) 189-217
16. Andersen D.H. Incidence of congenital diaphragmatic hernia in the young of rats bred on a diet deficient in vitamin A. Am J Dis Child 62 (1941) 888-889
17. Mendelsohn C., Lohnes D., Decimo D., et al. Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 120 (1994) 2749-2771
18. Major D., Cadenas M., Fournier L., et al. Retinol status of newborn infants with congenital diaphragmatic hernia. Pediatr Surg Int 13 (1998) 547-549
19. Mortell A., Montedonico S., and Puri P. Animal models in pediatric surgery. Pediatr Surg Int 22 (2006) 111-128
20. Thebaud B., Tibboel D., Rambaud C., et al. Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats. Am J Physiol 277 (1999) L423-L429
21. Babiuk R.P., Thebaud B., and Greer J.J. Reductions in the incidence of nitrofen-induced diaphragmatic hernia by vitamin A and retinoic acid. Am J Physiol Lung Cell Mol Physiol 286 (2004) L970-L973
22. Nakazawa N., Montedonico S., Takayasu H., et al. Disturbance of retinol transportation causes nitrofen induced hypoplastic lung. J Pediatr Surg 42 2 (2007) 345-349
23. Morris-Kay G.M. Treatment of mice with retinoids in vivo and in vitro. In: Sharpe P.Ta.M.I. (Ed). Molecular embryology: methods and protocols (1999), Humana Press Inc 33-39
24. Howard C.V., and Reed M. Unbiased stereology. Three-dimensional measurement in microscopy (2005), BIOS Scientific Publisher, New York 277
25. Burri P.H. Structural aspects of prenatal and postnatal development and growth of the lung. In: McDonald J.A. (Ed). Lung growth and development (1997), Marcel Dekker, New York 1-35
26. Adamson I.Y., and Bowden D.H. Derivation of type 1 epithelium from type 2 cells in the developing rat lung. Lab Invest 32 (1975) 736-745
27. Okabe T., Yorifuji H., Yamada E., et al. Isolation and characterization of vitamin-A-storing lung cells. Exp Cell Res 154 (1984) 125-135
28. Sannes P.L. Structural and functional relationships between type II pneumocytes and components of extracellular matrices. Exp Lung Res 17 (1991) 639-659
29. Maden M., and Hind M. Retinoic acid in alveolar development, maintenance and regeneration. Philos Trans R Soc Lond B Biol Sci 359 (2004) 799-808
30. McGowan S.E., and Torday J.S. The pulmonary lipofibroblast (lipid interstitial cell) and its contributions to alveolar development. Annu Rev Physiol 59 (1997) 43-62
31. Baptista M.J., Melo-Rocha G., Pedrosa C., et al. Antenatal vitamin A administration attenuates lung hypoplasia by interfering with early instead of late determinants of lung underdevelopment in congenital diaphragmatic hernia. J Pediatr Surg 40 (2005) 658-665
32. Gonzalez-Reyes S., Martinez L., Martinez-Calonge W., et al. Effects of antioxidant vitamins on molecular regulators involved in lung hypoplasia induced by nitrofen. J Pediatr Surg 41 (2006) 1446-1452
33. Dirami G., Massaro G.D., Clerch L.B., et al. Lung retinol storing cells synthesize and secrete retinoic acid, an inducer of alveolus formation. Am J Physiol Lung Cell Mol Physiol 286 (2004) L249-L256
34. Liu B., Harvey C.S., and McGowan S.E. Retinoic acid increases elastin in neonatal rat lung fibroblast cultures. Am J Physiol 265 (1993) L430-L437
35. Masuyama H., Hiramatsu Y., and Kudo T. Effect of retinoids on fetal lung development in the rat. Biol Neonate 67 (1995) 264-273
36. Shenai J.P., and Chytil F. Vitamin A storage in lungs during perinatal development in the rat. Biol Neonate 57 (1990) 126-132
37. Geevarghese S.K., and Chytil F. Depletion of retinyl esters in the lungs coincides with lung prenatal morphological maturation. Biochem Biophys Res Commun 200 (1994) 529-535
38. Bolender R.P., Hyde D.M., and Dehoff R.T. Lung morphometry: a new generation of tools and experiments for organ, tissue, cell, and molecular biology. Am J Physiol 265 (1993) L521-L548
39. Zoetis T., and Hurtt M.E. Species comparison of lung development. Birth Defects Res B Dev Reprod Toxicol 68 (2003) 121-124
40. Massaro G.D., Massaro D., Chan W.Y., et al. Retinoic acid receptor-beta: an endogenous inhibitor of the perinatal formation of pulmonary alveoli. Physiol Genomics 4 (2000) 51-57
41. Bourbon J., Boucherat O., Chailley-Heu B., et al. Control mechanisms of lung alveolar development and their disorders in bronchopulmonary dysplasia. Pediatr Res 57 (2005) 38R-46R
42. Oue T., Shima H., Guarino N., et al. Antenatal dexamethasone administration increases fetal lung DNA synthesis and RNA and protein content in nitrofen-induced congenital diaphragmatic hernia in rats. Pediatr Res 48 (2000) 789-793
43. Shima H., Ohshiro K., Taira Y., et al. Antenatal dexamethasone suppresses tumor necrosis factor-alpha expression in hypoplastic lung in nitrofen-induced diaphragmatic hernia in rats. Pediatr Res 46 (1999) 633-637
44. Bunton T.E., and Plopper C.G. Triamcinolone-induced structural alterations in the development of the lung of the fetal rhesus macaque. Am J Obstet Gynecol 148 (1984) 203-215
45. Willet K.E., Jobe A.H., Ikegami M., et al. Lung morphometry after repetitive antenatal glucocorticoid treatment in preterm sheep. Am J Respir Crit Care Med 163 (2001) 1437-1443
46. Tschanz S.A., Makanya A.N., Haenni B., et al. Effects of neonatal high-dose short-term glucocorticoid treatment on the lung: a morphologic and morphometric study in the rat. Pediatr Res 53 (2003) 72-80
47. Massaro G.D., and Massaro D. Retinoic acid treatment partially rescues failed septation in rats and in mice. Am J Physiol Lung Cell Mol Physiol 278 (2000) L955-L960
48. Shenai J.P., Chytil F., and Stahlman M.T. Vitamin A status of neonates with bronchopulmonary dysplasia. Pediatr Res 19 (1985) 185-188
49. Hustead V.A., Gutcher G.R., Anderson S.A., et al. Relationship of vitamin A (retinol) status to lung disease in the preterm infant. J Pediatr 105 (1984) 610-615
50. Shenai J.P., Kennedy K.A., Chytil F., et al. Clinical trial of vitamin A supplementation in infants susceptible to bronchopulmonary dysplasia. J Pediatr 111 (1987) 269-277
51. Pearson E., Bose C., Snidow T., et al. Trial of vitamin A supplementation in very low birth weight infants at risk for bronchopulmonary dysplasia. J Pediatr 121 (1992) 420-427
52. Tyson J.E., Wright L.L., Oh W., et al. Vitamin A supplementation for extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network. N Engl J Med 340 (1999) 1962-1968