-
1
-
-
0038011833
-
Evolving concepts of rheumatoid arthritis
-
Firestein, G. S. 2003. Evolving concepts of rheumatoid arthritis. Nature 423: 356-361.
-
(2003)
Nature
, vol.423
, pp. 356-361
-
-
Firestein, G.S.1
-
2
-
-
29144526644
-
Mcl-1 is essential for the survival of synovial fibroblasts in rheumatoid arthritis
-
Liu, H., P. Eksarko, V. Temkin, G. K. Haines, 3rd, H. Perlman, A. E. Koch, B. Thimmapaya, and R. M. Pope. 2005. Mcl-1 is essential for the survival of synovial fibroblasts in rheumatoid arthritis. J. Immunol. 175: 8337-8345.
-
(2005)
J. Immunol
, vol.175
, pp. 8337-8345
-
-
Liu, H.1
Eksarko, P.2
Temkin, V.3
Haines 3rd, G.K.4
Perlman, H.5
Koch, A.E.6
Thimmapaya, B.7
Pope, R.M.8
-
3
-
-
0034142176
-
Rheumatoid arthritis and p53: How oxidative stress might alter the course of inflammatory diseases
-
Tak, P. P., N. J. Zvaifler, D. R. Green, and G. S. Firestein. 2000. Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases. Immunol. Today 21: 78-82.
-
(2000)
Immunol. Today
, vol.21
, pp. 78-82
-
-
Tak, P.P.1
Zvaifler, N.J.2
Green, D.R.3
Firestein, G.S.4
-
4
-
-
0034114880
-
Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis
-
Franz, J. K., T. Pap, K. M. Hummel, M. Nawrath, W. K. Aicher, Y. Shigeyama, U. Muller-Ladner, R. E. Gay, and S. Gay. 2000. Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis. Arthritis Rheum. 43: 599-607.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 599-607
-
-
Franz, J.K.1
Pap, T.2
Hummel, K.M.3
Nawrath, M.4
Aicher, W.K.5
Shigeyama, Y.6
Muller-Ladner, U.7
Gay, R.E.8
Gay, S.9
-
5
-
-
0034467058
-
Activation of synovial fibroblasts in rheumatoid arthritis: Lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
-
Pap, T., J. K. Franz, K. M. Hummel, E. Jeisy, R. Gay, and S. Gay. 2000. Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction. Arthritis Res. 2: 59-64.
-
(2000)
Arthritis Res
, vol.2
, pp. 59-64
-
-
Pap, T.1
Franz, J.K.2
Hummel, K.M.3
Jeisy, E.4
Gay, R.5
Gay, S.6
-
6
-
-
34347385478
-
The roles of synoviolin in crosstalk between endoplasmic reticulum stress-induced apoptosis and p53 pathway
-
Yamasaki, S., N. Yagishita, K. Nishioka, and T. Nakajima. 2007. The roles of synoviolin in crosstalk between endoplasmic reticulum stress-induced apoptosis and p53 pathway. Cell Cycle 6: 1319-1323.
-
(2007)
Cell Cycle
, vol.6
, pp. 1319-1323
-
-
Yamasaki, S.1
Yagishita, N.2
Nishioka, K.3
Nakajima, T.4
-
7
-
-
18644375615
-
Increased AP-1 and NF-κB activation and recruitment with the combination of the proinflammatory cytokines IL-1β, tumor necrosis factor α and IL-17 in rheumatoid synoviocytes
-
Granet, C., W. Maslinski, and P. Miossec. 2004. Increased AP-1 and NF-κB activation and recruitment with the combination of the proinflammatory cytokines IL-1β, tumor necrosis factor α and IL-17 in rheumatoid synoviocytes. Arthritis Res. Ther. 6: R190-R198.
-
(2004)
Arthritis Res. Ther
, vol.6
-
-
Granet, C.1
Maslinski, W.2
Miossec, P.3
-
8
-
-
0036884944
-
Rheumatoid arthritis synoviocyte survival is dependent on Stat3
-
Krause, A., N. Scaletta, J. D. Ji, and L. B. Ivashkiv. 2002. Rheumatoid arthritis synoviocyte survival is dependent on Stat3. J. Immunol. 169: 6610-6616.
-
(2002)
J. Immunol
, vol.169
, pp. 6610-6616
-
-
Krause, A.1
Scaletta, N.2
Ji, J.D.3
Ivashkiv, L.B.4
-
9
-
-
0037236049
-
Control of fibroblast-like synoviocyte proliferation by macrophage migration inhibitory factor
-
Lacey, D., A. Sampey, R. Mitchell, R. Bucala, L. Santos, M. Leech, and E. Morand. 2003. Control of fibroblast-like synoviocyte proliferation by macrophage migration inhibitory factor. Arthritis Rheum. 48: 103-109.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 103-109
-
-
Lacey, D.1
Sampey, A.2
Mitchell, R.3
Bucala, R.4
Santos, L.5
Leech, M.6
Morand, E.7
-
10
-
-
35348822056
-
Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis
-
Sawai, H., Y. W. Park, X. He, J. J. Goronzy, and C. M. Weyand. 2007. Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis. Arthritis Rheum. 56: 3215-3225.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3215-3225
-
-
Sawai, H.1
Park, Y.W.2
He, X.3
Goronzy, J.J.4
Weyand, C.M.5
-
11
-
-
33847133943
-
Cadherin-11 in synovial lining formation and pathology in arthritis
-
Lee, D. M., H. P. Kiener, S. K. Agarwal, E. H. Noss, G. F. Watts, O. Chisaka, M. Takeichi, and M. B. Brenner. 2007. Cadherin-11 in synovial lining formation and pathology in arthritis. Science 315: 1006-1010.
-
(2007)
Science
, vol.315
, pp. 1006-1010
-
-
Lee, D.M.1
Kiener, H.P.2
Agarwal, S.K.3
Noss, E.H.4
Watts, G.F.5
Chisaka, O.6
Takeichi, M.7
Brenner, M.B.8
-
12
-
-
19944428920
-
Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes
-
Valencia, X., J. M. Higgins, H. P. Kiener, D. M. Lee, T. A. Podrebarac, C. C. Dascher, G. F. Watts, E. Mizoguchi, B. Simmons, D. D. Patel, et al. 2004. Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes. J. Exp. Med. 200: 1673-1679.
-
(2004)
J. Exp. Med
, vol.200
, pp. 1673-1679
-
-
Valencia, X.1
Higgins, J.M.2
Kiener, H.P.3
Lee, D.M.4
Podrebarac, T.A.5
Dascher, C.C.6
Watts, G.F.7
Mizoguchi, E.8
Simmons, B.9
Patel, D.D.10
-
13
-
-
34248595623
-
Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes
-
Tran, C. N., M. J. Davis, L. A. Tesmer, J. L. Endres, C. D. Motyl, C. Smuda, E. C. Somers, K. C. Chung, A. G. Urquhart, S. K. Lundy, et al. 2007. Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes. Arthritis Rheum. 56: 1497-1506.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1497-1506
-
-
Tran, C.N.1
Davis, M.J.2
Tesmer, L.A.3
Endres, J.L.4
Motyl, C.D.5
Smuda, C.6
Somers, E.C.7
Chung, K.C.8
Urquhart, A.G.9
Lundy, S.K.10
-
14
-
-
0035865197
-
Effector function of resting T cells: Activation of synovial fibroblasts
-
Yamamura, Y., R. Gupta, Y. Morita, X. He, R. Pai, J. Endres, A. Freiberg, K. Chung, and D. A. Fox. 2001. Effector function of resting T cells: activation of synovial fibroblasts. J. Immunol. 166: 2270-2275.
-
(2001)
J. Immunol
, vol.166
, pp. 2270-2275
-
-
Yamamura, Y.1
Gupta, R.2
Morita, Y.3
He, X.4
Pai, R.5
Endres, J.6
Freiberg, A.7
Chung, K.8
Fox, D.A.9
-
15
-
-
33745491185
-
Costimulatory pathways in rheumatoid synovitis and T-cell senescence
-
Goronzy, J. J., G. Henel, H. Sawai, K. Singh, E. B. Lee, S. Pryshchep, and C. M. Weyand. 2005. Costimulatory pathways in rheumatoid synovitis and T-cell senescence. Ann. NY Acad. Sci. 1062: 182-194.
-
(2005)
Ann. NY Acad. Sci
, vol.1062
, pp. 182-194
-
-
Goronzy, J.J.1
Henel, G.2
Sawai, H.3
Singh, K.4
Lee, E.B.5
Pryshchep, S.6
Weyand, C.M.7
-
16
-
-
18644371735
-
T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis
-
Sawai, H., Y. W. Park, J. Roberson, T. Imai, J. J. Goronzy, and C. M. Weyand. 2005. T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis. Arthritis Rheum. 52: 1392-1401.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1392-1401
-
-
Sawai, H.1
Park, Y.W.2
Roberson, J.3
Imai, T.4
Goronzy, J.J.5
Weyand, C.M.6
-
18
-
-
0042591425
-
Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction
-
Vallejo, A. N., H. Yang, P. A. Klimiuk, C. M. Weyand, and J. J. Goronzy. 2003. Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction. J. Immunol. 171: 1732-1740.
-
(2003)
J. Immunol
, vol.171
, pp. 1732-1740
-
-
Vallejo, A.N.1
Yang, H.2
Klimiuk, P.A.3
Weyand, C.M.4
Goronzy, J.J.5
-
19
-
-
0041422233
-
Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis
-
Groh, V., A. Bruhl, H. El-Gabalawy, J. L. Nelson, and T. Spies. 2003. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 100: 9452-9457.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 9452-9457
-
-
Groh, V.1
Bruhl, A.2
El-Gabalawy, H.3
Nelson, J.L.4
Spies, T.5
-
20
-
-
15444370901
-
Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes
-
Inoue, T., D. Hammaker, D. L. Boyle, and G. S. Firestein. 2005. Regulation of p38 MAPK by MAPK kinases 3 and 6 in fibroblast-like synoviocytes. J. Immunol. 174: 4301-4306.
-
(2005)
J. Immunol
, vol.174
, pp. 4301-4306
-
-
Inoue, T.1
Hammaker, D.2
Boyle, D.L.3
Firestein, G.S.4
-
21
-
-
0032505870
-
NF-κB activation provides the potential link between inflammation and hyperplasia in the arthritic joint
-
Miagkov, A. V., D. V. Kovalenko, C. E. Brown, J. R. Didsbury, J. P. Cogswell, S. A. Stimpson, A. S. Baldwin, and S. S. Makarov. 1998. NF-κB activation provides the potential link between inflammation and hyperplasia in the arthritic joint. Proc. Natl. Acad. Sci. USA 95: 13859-13864.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13859-13864
-
-
Miagkov, A.V.1
Kovalenko, D.V.2
Brown, C.E.3
Didsbury, J.R.4
Cogswell, J.P.5
Stimpson, S.A.6
Baldwin, A.S.7
Makarov, S.S.8
-
22
-
-
18144416502
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt
-
Morel, J., R. Audo, M. Hahne, and B. Combe. 2005. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt. J. Biol. Chem. 280: 15709-15718.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15709-15718
-
-
Morel, J.1
Audo, R.2
Hahne, M.3
Combe, B.4
-
23
-
-
0141676444
-
Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK
-
Sundarrajan, M., D. L. Boyle, M. Chabaud-Riou, D. Hammaker, and G. S. Firestein. 2003. Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK. Arthritis Rheum. 48: 2450-2460.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2450-2460
-
-
Sundarrajan, M.1
Boyle, D.L.2
Chabaud-Riou, M.3
Hammaker, D.4
Firestein, G.S.5
-
24
-
-
0034944752
-
Regulation of tumor necrosis factor α-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt
-
Zhang, H. G., Y. Wang, J. F. Xie, X. Liang, D. Liu, P. Yang, H. C. Hsu, R. B. Ray, and J. D. Mountz. 2001. Regulation of tumor necrosis factor α-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt. Arthritis Rheum. 44: 1555-1567.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1555-1567
-
-
Zhang, H.G.1
Wang, Y.2
Xie, J.F.3
Liang, X.4
Liu, D.5
Yang, P.6
Hsu, H.C.7
Ray, R.B.8
Mountz, J.D.9
-
25
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta, S. R., A. Brunet, and M. E. Greenberg. 1999. Cellular survival: a play in three Akts. Genes Dev. 13: 2905-2927.
-
(1999)
Genes Dev
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
27
-
-
0036171199
-
Activation of the PKB/AKT pathway by ICAM-2
-
Perez, O. D., S. Kinoshita, Y. Hitoshi, D. G. Payan, T. Kitamura, G. P. Nolan, and J. B. Lorens. 2002. Activation of the PKB/AKT pathway by ICAM-2. Immunity 16: 51-65.
-
(2002)
Immunity
, vol.16
, pp. 51-65
-
-
Perez, O.D.1
Kinoshita, S.2
Hitoshi, Y.3
Payan, D.G.4
Kitamura, T.5
Nolan, G.P.6
Lorens, J.B.7
-
28
-
-
0033594950
-
Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway
-
Gautreau, A., P. Poullet, D. Louvard, and M. Arpin. 1999. Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway. Proc. Natl. Acad. Sci. USA 96: 7300-7305.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7300-7305
-
-
Gautreau, A.1
Poullet, P.2
Louvard, D.3
Arpin, M.4
-
30
-
-
9144259305
-
Prognostic markers of radiographic progression in early rheumatoid arthritis
-
Goronzy, J. J., E. L. Matteson, J. W. Fulbright, K. J. Warrington, A. Chang-Miller, G. G. Hunder, T. G. Mason, A. M. Nelson, R. M. Valente, C. S. Crowson, et al. 2004. Prognostic markers of radiographic progression in early rheumatoid arthritis. Arthritis Rheum. 50: 43-54.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 43-54
-
-
Goronzy, J.J.1
Matteson, E.L.2
Fulbright, J.W.3
Warrington, K.J.4
Chang-Miller, A.5
Hunder, G.G.6
Mason, T.G.7
Nelson, A.M.8
Valente, R.M.9
Crowson, C.S.10
-
31
-
-
0036636094
-
Apoptosis as a therapeutic tool in rheumatoid arthritis
-
Pope, R. M. 2002. Apoptosis as a therapeutic tool in rheumatoid arthritis. Nat Rev. Immunol. 2: 527-535.
-
(2002)
Nat Rev. Immunol
, vol.2
, pp. 527-535
-
-
Pope, R.M.1
-
32
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
Downward, J. 1998. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10: 262-267.
-
(1998)
Curr. Opin. Cell Biol
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
33
-
-
33646695439
-
Role of adhesion molecules in synovial inflammation
-
Agarwal, S. K., and M. B. Brenner. 2006. Role of adhesion molecules in synovial inflammation. Curr. Opin. Rheumatol. 18: 268-276.
-
(2006)
Curr. Opin. Rheumatol
, vol.18
, pp. 268-276
-
-
Agarwal, S.K.1
Brenner, M.B.2
-
34
-
-
0032521147
-
Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo
-
Oppenheimer-Marks, N., R. I. Brezinschek, M. Mohamadzadeh, R. Vita, and P. E. Lipsky. 1998. Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo. J. Clin. Invest. 101: 1261-1272.
-
(1998)
J. Clin. Invest
, vol.101
, pp. 1261-1272
-
-
Oppenheimer-Marks, N.1
Brezinschek, R.I.2
Mohamadzadeh, M.3
Vita, R.4
Lipsky, P.E.5
-
35
-
-
33644872811
-
LFA-1 (CD11a) as a therapeutic target
-
Nicolls, M. R., and R. G. Gill. 2006. LFA-1 (CD11a) as a therapeutic target. Am. J. Transplant. 6: 27-36.
-
(2006)
Am. J. Transplant
, vol.6
, pp. 27-36
-
-
Nicolls, M.R.1
Gill, R.G.2
-
37
-
-
14844339399
-
Manifestations of inflammatory arthritis are critically dependent on LFA-1
-
Watts, G. M., F. J. Beurskens, I. Martin-Padura, C. M. Ballantyne, L. B. Klickstein, M. B. Brenner, and D. M. Lee. 2005. Manifestations of inflammatory arthritis are critically dependent on LFA-1. J. Immunol. 174: 3668-3675.
-
(2005)
J. Immunol
, vol.174
, pp. 3668-3675
-
-
Watts, G.M.1
Beurskens, F.J.2
Martin-Padura, I.3
Ballantyne, C.M.4
Klickstein, L.B.5
Brenner, M.B.6
Lee, D.M.7
-
38
-
-
0032568580
-
Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels
-
Wulfing, C., M. D. Sjaastad, and M. M. Davis. 1998. Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels. Proc. Natl. Acad. Sci. USA 95: 6302-6307.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6302-6307
-
-
Wulfing, C.1
Sjaastad, M.D.2
Davis, M.M.3
-
39
-
-
0030027479
-
Responsiveness of human T lymphocytes to bacterial superantigens presented by cultured rheumatoid arthritis synoviocytes
-
Tsai, C., L. A. Diaz, Jr., N. G. Singer, L. L. Li, A. H. Kirsch, R. Mitra, B. J. Nickoloff, L. J. Crofford, and D. A. Fox. 1996. Responsiveness of human T lymphocytes to bacterial superantigens presented by cultured rheumatoid arthritis synoviocytes. Arthritis Rheum. 39: 125-136.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 125-136
-
-
Tsai, C.1
Diaz Jr., L.A.2
Singer, N.G.3
Li, L.L.4
Kirsch, A.H.5
Mitra, R.6
Nickoloff, B.J.7
Crofford, L.J.8
Fox, D.A.9
-
40
-
-
33749446861
-
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis
-
Paniagua, R. T., O. Sharpe, P. P. Ho, S. M. Chan, A. Chang, J. P. Higgins, B. H. Tomooka, F. M. Thomas, J. J. Song, S. B. Goodman, et al. 2006. Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis. J. Clin. Invest. 116: 2633-2642.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 2633-2642
-
-
Paniagua, R.T.1
Sharpe, O.2
Ho, P.P.3
Chan, S.M.4
Chang, A.5
Higgins, J.P.6
Tomooka, B.H.7
Thomas, F.M.8
Song, J.J.9
Goodman, S.B.10
-
41
-
-
0029958821
-
- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity
-
- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J. Clin. Invest. 97: 2027-2037.
-
(1996)
J. Clin. Invest
, vol.97
, pp. 2027-2037
-
-
Schmidt, D.1
Goronzy, J.J.2
Weyand, C.M.3
-
42
-
-
24744435115
-
Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
-
Camps, M., T. Ruckle, H. Ji, V. Ardissone, F. Rintelen, J. Shaw, C. Ferrandi, C. Chabert, C. Gillieron, B. Francon, et al. 2005. Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat. Med. 11: 936-943.
-
(2005)
Nat. Med
, vol.11
, pp. 936-943
-
-
Camps, M.1
Ruckle, T.2
Ji, H.3
Ardissone, V.4
Rintelen, F.5
Shaw, J.6
Ferrandi, C.7
Chabert, C.8
Gillieron, C.9
Francon, B.10
|