Oral treatment for gastric cancer: new choices, better choices?

The Lancet Oncology

Volumn 9, Issue 3, 2008, Pages 188-189

  Cascinu, Stefanu ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR; CAPECITABINE; CISPLATIN; DOCETAXEL; EPIRUBICIN; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; IRINOTECAN; OXALIPLATIN; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; DRUG DERIVATIVE; OXONIC ACID; S 1 (COMBINATION); TEGAFUR; UNCLASSIFIED DRUG;

ADVANCED CANCER; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER SURVIVAL; CLINICAL PRACTICE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTINUOUS INFUSION; DRUG EFFICACY; DRUG SAFETY; GASTRECTOMY; HUMAN; LETTER; METASTASIS; MONOTHERAPY; NEUTROPENIA; PRIORITY JOURNAL; STOMACH CANCER; DRUG COMBINATION; JAPAN; MORTALITY; NOTE; ORAL DRUG ADMINISTRATION; PHASE 3 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; STOMACH TUMOR; SURVIVAL RATE;

ADMINISTRATION, ORAL; ANTIMETABOLITES, ANTINEOPLASTIC; CLINICAL TRIALS, PHASE III AS TOPIC; DEOXYCYTIDINE; DRUG COMBINATIONS; FLUOROURACIL; HUMANS; JAPAN; OXONIC ACID; RANDOMIZED CONTROLLED TRIALS AS TOPIC; STOMACH NEOPLASMS; SURVIVAL RATE; TEGAFUR;

EID: 40749137800     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(08)70042-1     Document Type: Letter

References (12)

1. Van Cutsem E., Moiseyenko V., Tjulandin S., et al. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer a report of the V325 Study Group. J Clin Oncol 24 (2006) 4991-4997
2. Dank M., Zaluski J., Barone C., et al. Randomised phase III trial of irinotecan + 5FU/folinic acid versus CDDP/5FU in 1st-line advanced gastric cancer. J Clin Oncol 23 (2006) 308
3. Louvet C., Andre' T., Tigaud J., et al. Phase II study of oxaliplatin, fluorouracil, and folinic acid in locally advanced or metastatic gastric cancer. J Clin Oncol 20 (2002) 4543-4548
4. Cunningham D., Starling N., Rao S., et al. Capecitabine and oxaliplatin for advanced esophagogastric cancer. New Engl J Med 358 (2008) 36-46
5. Kang Y., Kang W., Shin D., et al. Randomized phase III trial of capecitabine/cisplatin (XP) versus continuous infusion of 5FU/cisplatin (FP) as first-line therapy in patients with advanced gastric cancer: efficacy and safety results. J Clin Oncol 23 (2006) 4018
6. Shirasaka T., Shiramato Y., Ohshimo H., et al. Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumour selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs 7 (1996) 548-557
7. Boku N., Yamamoto S., Shirao K., et al. Randomised phase III study of 5-fluorouracil alone versus combination of irinotecan and cisplatin versus S-1 alone in advanced gastric cancer (JCOG9912). J Clin Oncol 25 (2007) 965s (abstr).
8. Koizumi W., Narahara H., Hara T., et al. Randomised controlled trial of S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial. Lancet Oncol 9 (2008) 215-221
9. Lenz H., Lee F., Haller D., et al. Expanded safety and efficacy data on S-1 plus cisplatin in patients with untreated, advanced gastric carcinoma in a multicenter phase II study. Cancer 109 (2007) 33-40
10. Ross P., Nicolson M., Cunningham D., et al. Prospective randomised trial of comparing mytomicin, cisplatin and protracted venous-infusion fluorouracil (PVI-5FU) with epirubicin, cisplatin and PVI 5-FU in advanced esophago-gastric cancer. J Clin Oncol 20 (2002) 1996-2004
11. Wagner A., Grothe W., Haerting J., et al. Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data. J Clin Oncol 24 (2006) 2903-2909
12. Kang Y., Lee J., Min K., et al. A randomized multi-center phase II trial of capecitabine versus S-1 as first-line treatment in elderly patients with metastatic or recurrent unresectable gastric cancer. J Clin Oncol 25 (2007) 4546