Relaxant effect of Satureja hortensis on guinea pig tracheal chains and its possible mechanism(s)

Daru

Volumn 15, Issue 4, 2007, Pages 199-204

  Boskabady, M H ^a   Aslani, M R ^a   Mansuri, F ^a   Amery, S ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Bronchodilatory; Guinea pig; Satureja hortensis; Trachea

Indexed keywords

ALCOHOL; ATROPINE; CHLORPHENIRAMINE; METHACHOLINE; PLANT EXTRACT; POTASSIUM CHLORIDE; PROPRANOLOL; SATUREJA HORTENSIS EXTRACT; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHODILATATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GUINEA PIG; MALE; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; SATUREJA HORTENSIS; SAVORY; TRACHEA MUSCLE;

EID: 40749109412     PISSN: 15608115     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Zargari A, Medicinal plants.Vol.2. 5th ed. Tehran University publications. Tehran (1992) 281-284.
2. Paskov D, Drianovska-Noninska L. Chemical and pharmacological studies on Satureia hortensis L. Farmatsiia 1954; 4: 31-37
3. Radonic A, Milos M. Chemical composition and antioxidant test of free and glycosidically bound volatile compounds of savory (Satureja montana L. subsp. montana) from Croatia. Nahrung 2003; 47: 236-7.
4. Baser K H C, Özek T, Kirimer N, Tümen G. A Comparative Study of the Essential Oils of Wild and Cultivated Satureja hortensis L. J Essential Oil Res 2004; 9: 1-4.
5. Gulluce M, Sokmen M, Daferera D, Agar G, Ozkan H, Kartal N, Polissiou M, Sokmen A, Sahin F. In vitro antibacterial, antifungal, and antioxidant activities of the essential oil and methanol extracts of herbal parts and callus cultures of Satureja hortensis L. J Agric Food Chem 2003; 51: 958-65.
6. Sahin F, Karaman I, Gulluce M, Ogutcu H, Sengul M, Adiguzel A, Ozturk S, Kotan R. Evaluation of antimicrobial activities of Satureja hortensis L. J Ethnopharmacol 2003; 87: 61-65.
7. Lindberg HM, Andersen L, Christiansen L, Brockhoff P and Bertelsen G. Antioxidative activity of summer savory (Satureja hortensis L.) and rosemary (Rosmarinus officinalis L.) in minced, cooked pork meat. Zeitschrift für Lebensmitteluntersuchung und -Forschung A 1996; 1431-4630.
8. Kuchukashvili Z, Davitaia I, Gorozia G, Kvesitadze E, Lomidze G, Khatisashvili. Antioxidant characteristics of phenolic compounds of Satureia hortensis. J Biol Phys Chem 2003; 3: 5-88.
9. Kuchukashvili Z, A valiani N, Davitaia, G. Influence of Flavonoid fraction from satureja hortensis on microsomal oxidation. Proceeding od of the Georgian Academy of Sceinces 2003; 1-18.
10. Shipochliev T. Pharmacological study of several essential oils. I. Effect on the smooth muscle. Vet-Med Nauki 1968; 5: 63-9.
11. Hajhashemi V, Sadraei H, Ghannadi AR, Mohseni M. Antispasmodic and anti-diarrhoeal effect of Satureja hortensis L. essential oil. J Ethnopharmacol 2000; 71: 187-192.
12. Yamasaki K, Nakano M, Kawahata T, Mori H, Otake T, Ueba N, Oishi I, Inami R, Yamane M, Nakamura M, Murata H, Nakanishi T. Anti-HIV-1 activity of herbs in Labiatae. Biol Pharm Bull 1998; 21: 829-33.
13. Mchedlishvili D, Kuchukashvili Z, Tabatadze T, Davitaia G. Influence of flavonoids isolated from Satureja hortensis L. on hypercholesterolemic rabbits. Ind J Pharmacol 2005; 37: 259-260.
14. Holroyde MC. The influence of epithelium on the responsiveness of guinea pig isolated trachea. Br J Pharmacol 1986; 87:501-507.
15. 3 adrenoceptor agonists, BRL 37344 and SR 58611A do not induce relaxation of human, sheep and guinea pig airway smooth muscle in vitro. Eur Respir J 1994; 7: 1610-1615.
16. Linden A, Bergendal A, Ullman A, Skoogh BE, Lofdahl CG. Salmetrol, formetrol, and salbutamol in the isolated guinea-pig trachea: differences in maximum relaxant effect and potency but not in functional antagonism. Thorax 1993; 48: 547-553.
17. Popa VT, Somani P, Simon P, Simon V. The effect of inhaled verapamil on resting bronchial tone and airway constriction by histamine and acetylcholine in normal and asthmatic subjects. Am Rev Respir Dis 1984; 130: 106-113.
18. 3 muscarinic receptor inhibit smooth muscle contraction in rabit trachea without increasing the release of acetylcholine. J Pharmacol Exp Ther 1992; 263: 773-770.
19. Perez-Guerrero C, Suarez J, Herrera MD, Marhuenda E. Spasmolytic effect of tetrazepam on rat duodenum and guinea pig ileum. Pharmacol Res 1997; 35: 493-494.
20. 2+ antagonists on acetylcholine induced contraction in molluscan (Mytilus edulis) smooth muscle. Gen Pharmacol 1993; 24: 1419-1423.
21. 2+ modulator in normal and albumin sensitised guinea pig trachea. Eur J Pharmacol 1993; 249: 53-63.
22. Buckle DR, Arch JRS, Boering NE,Foster KA, Taylor JF, Taylor SG, Shaw DJ. Relaxation effect of potassium channel activators BRL 38227 and Pinacidil on guinea pig and human airway smooth muscle, and blockade of their effects by Glibenclamide and BRL 31660. Pulmon Pharmacol 1993; 6: 77-86.
23. Boskabady MH, Jandaghi P. Relaxant effect of carvacrol on guinea pig tracheal chainsand its possible mechanisms. Pharmazie 2003; 58: 661-663.
24. Boskabady MH, Rakhshandah H, Moetamedshariati V. Bronchodilatory and anticholinergic effects of Carum copticum on isolated guinea pig tracheal chains. Med J I R Iran 1998; 11: 329-334.