Isotype switching and titer variation of anti-Ro/SSA antibodies over time in 100 patients with undifferentiated connective tissue disease (UCTD)

Clinical and Experimental Rheumatology

Volumn 26, Issue 1, 2008, Pages 117-120

  Ceribelli, Angela ^a,b   Cavazzana, Ilaria ^a   Franceschini, Franco ^a   Quinzanini, Marzia ^a   Rizzini, Fabio Lodi ^a   Cattaneo, Roberto ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b Servizio di Reumatologia e Immunologia Clinica   (Italy)

Author keywords

Anti Ro SSA antibodies; Antibody titer; Isotype switching; Sj gren's syndrome; Systemic lupus erythematosus; Undifferentiated connective tissue disease

Indexed keywords

IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; RECOMBINANT PROTEIN; RO ANTIBODY;

ADULT; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; COHORT ANALYSIS; CONNECTIVE TISSUE DISEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; COUNTER IMMUNOELECTROPHORESIS; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; SJOEGREN SYNDROME; UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE;

AUTOANTIBODIES; AUTOANTIGENS; CONNECTIVE TISSUE DISEASES; COUNTERIMMUNOELECTROPHORESIS; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MIDDLE AGED; RIBONUCLEOPROTEINS; RNA, SMALL CYTOPLASMIC; SJOGREN'S SYNDROME;

EID: 40749105733     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. MOSCA M, NERI R, BOMBARDIERI S: Undifferentiated connective tissue disease (UCTD): A review of the literature and a proposal for preliminary classification criteria. Clin Exp Rheumatol 1999; 17: 615-20.
2. DORIA A, MOSCA M, GAMBARI PF, BOMBARDIERI S: Defining unclassifiable connective tissue diseases: Incomplete, undifferentiated, or both? J Rheumatol 2005; 32: 213-5.
3. CLEGG DO, WILLIAMS JH, SINGER JZ et al.: Early undifferentiated connective tissue disease II. The frequency of circulating antinuclear antibodies in patients with early rheumatic diseases. J Rheumatol 1991; 18: 1340-43.
4. MOSCA M, TAVONI A, NERI R, BENCIVELLI W, BOMBARDIERI S: Undifferentiated connective tissue diseases: The clinical and serological profiles of 91 patients followed for at least one year. Lupus 1998; 2: 95-100.
5. DANIELI MG, FRATICELLI P, FRANCESCHINI F et al.: Five-year follow-up of 165 Italian patients with undifferentiated connective tissue diseases. Clin Exp Rheumatol 1999; 17: 585-91.
6. SCOFIELD RH, ZHANG F, KURIEN BT et al.: Development of the anti-Ro autoantibody response in a patient with systemic lupus erythematosus. Arthritis Rheum 1996; 39: 1664-8.
7. ARBUCKLE MR, McCLAIN MT, RUBERTONE MV et al.: Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003; 349: 1526-33.
8. BERNSTEIN RM, BUNN CC, HUGHES GRV: Identification of antibodies to acidic antigens by counterimmunoelectrophoresis. Ann Rheum Dis 1982; 41: 554-5.
9. CLARK G, REICHLIN M, TOMASI TB: Characterization of a soluble cytoplasmic antigen reactive with sera from patients with systemic lupus erythematosus. J Immunol 1969; 102: 117-22.
10. VENABLES PJW, SMITH PR, MAINI RN: Purification and characterization of the Sjögren's Syndrome A and B antigens. Clin Exp Immunol 1983; 54: 731-8.
11. WAHREN M, RINGERTZ NR, PETTERSSON I: IgM and IgG subclass distribution of human anti-Ro/SSA 60 kDa autoantibodies. Scand J Immunol 1994; 39: 179-83.
12. POURMAND N, WAHREN-HERLENIUS M, GUNNARSSON I et al.: Ro/SSA and La/SSB specific IgA autoantibodies in serum of patients with Sjögren's syndrome and systemic lupus erythematosus. Ann Rheum Dis 1999; 58: 623-9.