Role of zinc in hemostasis: A review

Biological Trace Element Research

Volumn 121, Issue 1, 2008, Pages 1-8

  Tubek, Sławomir ^a   Grzanka, Piotr ^b   Tubek, Iwona ^a  

^a UNIVERSITY OF OPOLE   (Poland)

^b UNIVERSITY HOSPITAL IN KRAKOW   (Poland)

Author keywords

Clotting factors; Hemostasis; Platelets; Shear stress; Zinc

Indexed keywords

ANTITHROMBIN; BLOOD CLOTTING FACTOR; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 7; FIBRIN; FIBRINOGEN; HEPARIN; PLASMIN; PLASMINOGEN; PROTHROMBIN; THROMBIN; ZINC;

BLEEDING TIME; BLOOD CLOTTING DISORDER; BLOOD FLOW; CATALYSIS; CELL INTERACTION; DIET SUPPLEMENTATION; HEMATOPOIESIS; HEMOSTASIS; HUMAN; MEN'S HEALTH; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; REVIEW; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; ZINC BLOOD LEVEL; ZINC DEFICIENCY;

ANIMALS; BLOOD CIRCULATION; BLOOD COAGULATION; BLOOD PLATELETS; FACTOR VII; FACTOR XI; FACTOR XII; FIBRIN; FIBRINOGEN; HEMATOPOIESIS; HEMOSTASIS; HEPARIN; HUMANS; PROTHROMBIN; ZINC;

EID: 40749085676     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12011-007-8038-y     Document Type: Review

References (62)

1. Gordon PR, Woodruff CW, Anderson HL, O'Dell BL (1982) Effects of acute zinc deprivation on plasma zinc and platelet aggregation in adult males. Am J Clin Nutr 35:849-857
2. Vallee BL, Falchuk KH (1993) The biochemical basis of zinc physiology. Physiol Rev 73:79-87
3. Kokot F, Tatoń J (1991) In: Kokota F (ed) Zaburzenia przemiany materii w "Chorobach Wewnȩtrznych" pod red. PZWL, Warszawa, p 670
4. Holtmeier HJ, Kuhn M, Rummel K (1976) Zink ein lebenswichtiges Mineral. Wissenschaftliche Verlagsgeselschaft MbH, Stuttgart, p 13
5. Turner AJ, Brown CD, Carson JA, Barens K (2000) The neprilysin family in health and disease. Adv Exp Med Biol 477:229-240
6. Kulikowska E, Moniuszko-Jakoniuk J, Miniuk K (1991) Rola cynku w procesach fizjologicznych i patologicznych organizmu. Pol Tyg Lek 46:471-475
7. Cousins RJ (1986) Toward a molecular understanding of zinc metabolism. Clin Physiol Biochem 4:20-30
8. O'Dell BL (2000) Role of zinc in plasma membrane function. J Nutr 130:1432S-1436S
9. Avery RA, Bettger WJ (1992) Zinc deficiency alters the protein composition of the membrane skeleton but not the extractability or oligomeric form of spectrin in rat erythrocyte membranes. J Nutr 122:428-433
10. Bettger WJ, O'Dell BL (1981) A critical physiological role of zinc in the structure and function of biomembranes. Life Sci 28:1425-1438
11. Carvalho A (1972) Binding and release of cations by sarcoplasmic reticulum before and after removal of lipids. Eur J Biochem 27:491-496
12. Driscoll ER, Bettger WJ (1992) Zinc deficiency in the rat alters the lipid composition of the erythrocyte membrane Triton shell. Lipids 27:972-977
13. Harrison NL, Radke HK, Tamkun MM, Lovinger DM (1993) Modulation of gating of cloned rat and human K+ channels by micromolar Zn+2. Mol Pharmacol 43:482-490
14. a. Heinemann SH, Struhnar W, Molecular structure of potassium and sodium channels and their structure-function correlation, p 109-112
15. b. Nilins B, Droogmans G, Ion channels of endothelial cells, p 964, in Physiology and pathophysiology of the heart, Sparelakis N (1995) 3rd ed., Kluwer, Dortrecht
16. Maccara IG (1985) Oncogenesis, ions and phospholipids. Am J Physiol 248:C3-C8
17. Dorup I, Clausen T (1991) Effects of magnesium and zinc deficiencies on growth and protein synthesis in skeletal muscle and the heart. Br J Nutr 66:493-504
18. Csermely P, Somogyi J (1989) Zinc as a possible mediator of signal transduction in T lymphocytes. Acta Physiol Hung 74:195-199
19. Csermely P, Sandor P, Radics L, Somogyi J (1989) Zinc forms complexes with higher kinetical stability than calcium, 5-F-BAPTA as a good example. Biochem Biophys Res Commun 165:838-843
20. Girchev R, Tzachev K (1998) Metabolism and homeostasis of zinc and copper. Acta Physiol Pol 39(supl. 32):103-112
21. McMaster D, McCrum E, Patterson CC (1992) Serum copper and zinc in random samples of the population of Northen Ireland. Am J Clin Nutr 56:440-445
22. Gorodetsky R, Mou X, Blankenfeld A, Marx G (1993) Platelet multielemental composition, lability and subcellular localization. Am J Hematol 42:278-283
23. Marx G, Eldor A (1985) The procoagulant effect of zinc on fibrin clot formation. Am J Hematol 19:151-159
24. Hughes S, NutrDiet M, Samman S (2006) The effect of zinc supplementation in humans on plasma lipids, antioxidant status and thrombogenesis. J Am Coll Nutr 25:285-291
25. Bernardo MM, Day DE, Olson ST, Halvorson HR, Shore JD (1993) Surface-independent acceleration of factor XII activation by zinc ions. I. Kinetic characterization of the metal ion rate enhancement. J Biol Chem 268:12468-12476
26. Bernardo MM, Day DE, Olson ST, Halvorson HR, Shore JD (1993) Surface-independent acceleration of factor XII activation by zinc ions. II. Direct binding and fluorescence studies. J Biol Chem 268:12477-12483
27. Schousboe I (1990) The inositol-phospholipid-accelerated activation of prekallikrein by activated factor XII at physiological ionic strength zinc ions and high-Mr kininogen. Eur J Bichem 193:495-499
28. Shimada T, Kato H, Iwanaga S (1987) Accelerating effect of zinc ions on the surface-mediated activation of factor XII and prekallikrein. J Biochem 102:913-921
29. Shore JD, Day DE, Bock PE, Olson ST (1987) Acceleration of surface-dependent autocatalytic activation of blood coagulation factor XII by divalent metal ions. Biochemistry 26:2250-2258
30. Reddigari SR, Shibayama Y, Brunnee T, Kaplan AP (1993) Human Hageman factor (Factor XII) and high molecular weight kininogen compete for the same binding site on human umbilical vein endothelial cells. J Biol Chem 268:11982-11987
31. Silverberg M, Diehl SV (1987) The autoactivation of factor XII (Hageman factor) induced by low-Mr heparin and dextran sulphate. The effect of the Mr of the activating polyanion. Biochem J 248:715-720
32. Samuel M, Pixley RA, Villanueva MA, Colman RW, Vullanueva GB (1992) Human factor XII (Hageman factor) autoactivation by dextran sulfate. Circular dichroism, fluorescence, and ultraviolet difference spectroscopic studies. J Biol Chem 267:19691-19697
33. Petersen LC, Olsen OH, Nielsen LS, Freskgard P, Persson E (2000) Binding of Zn2+ to a Ca2+ loop alloserically attenuates the activity of factor VIIa and reduces its affinity for tissue factor. Protein Sci 9:859-866
34. Gailani D, Broze GJ Jr (1991) Factor XI activation in a revised model of blood coagulation. Science 253:909-912
35. Baglia FA, Badellino KO, Ho DH, Dasari VR, Walsh PN (2000) A binding site for the kringle II domain of prothrombin in the apple 1 domain of factor XI. J Biol Chem 275:31954-31962
36. Baglia FA, Gailani D, Lopez JA, Walsh PN (2004) Identification of a binding site for glycoprotein Ibα in Apple 3 domain of factor XI. J Biol Chem 279:24270-45476
37. Greengard JS, Heeb MJ, Ersdal E, Walsh PN, Griffin JH (1986) Binding of coagulation factor XI to washed human platelets. Biochem 25:3884-3890
38. Baird TR, Walsh PN (2002) Activated platelets but not endothelial cell participate in the initiation of the consolidation phase of blood coagulation. J Biol Chem 277:28498-24503
39. Van Nostrand WE (1995) Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid beta-protein precursor. Thromb Res 78:43-53
40. Mahdi F, Shariat-Madar Z, Schmaier AH (2003) The relative priority of prekallikrein and factors XI/XIa assembly on cultured endothelial cells. J Biol Chem 278:43983-43990
41. Rojkjaer R, Schmaier AH (1999) Activation of the plasma kallikrein/kinin system on endothelial cell membranes. Immunopharmacology 43:109-114 (Abstract)
42. Kluszynski BA, Kim C, Faulk WP (1997) Zinc as a cofactor for heparin neutralization by histidine -rich glycoprotein. J Biol Chem 272:13541-13547
43. Marx G (1988) Divalent cations induce protofibril gelation. Am J Hekamtol 27:104-109
44. Hopmeier P, Halbmayer M, Fischer M, Marx G (1990) Zinc modulates thrombin adsorption to fibrin. Thromb Res 58:293-301
45. Dugan TA, Yang VW-C, McQuillan DJ, Höök M (2006) Decorin modulates fibrin assembly and structure. J Biol Chem 281:38208-38216
46. O'Dell BL (2000) Role of zinc in plasma membrane function. J Nutr 130:1432S-1436S
47. Kimura Y, Hart A, Hirashima M et al (2002) Zinc finger protein, Hzf, is required for megakaryocyte development and hemostasis. J Exp Med 195:941-952
48. 2+ mediates strong and specific interaction of single-chain urokinase with fibrin. J Biol Chem 268:8574-8579
49. Jones AL, Hulett MD, Altin JG, Hogg Ph, Parish ChR (2004) Plasminogen is tethered with high affinity to the cell surface by the plasma protein, histidine-rich glycoprotein. J Biol Chem 279:38267-38276
50. Lijnen HR (2001) Elements of the fibrinolytic system. Ann N Y Acad Sci 936:226-236
51. Marx PF, Bouma BN, Meijers JC (2002) Role of zinc ions in activation and inactivation of thrombin-activatable fibrinolysis inhibitor. Biochemistry 41:1211-1216
52. Mahdi F, Madar ZS, Figueroa CD, Schmaier AH (2002) Factor XII interacts with the multiprotein assembly of urokinase plasminogen activator receptor, gC1qR, and cytoceratin 1 on endothelial cell membranes. Blood 99:3585-3596
53. Schousboe I (1997) Factor XIIa activation of plasminogen is enhanced by contact activating surfaces and Zn2+. Blood Coagul Fibrinolysis 8:97-104
54. Kaji T (2004) Cell biology of heavy metal toxicity in vascular tissue. Yakugaku Zasshi 124:113-120 (Abstract)
55. Tao J, Yang Z, Wang JM, Luo CF, Tang AL, Dong GY, Ma H (2007) Shear stress increases Cu/Zn SOD activity and mRNA expression in human endothelial progenitor cells. J Hum Hypertens 21:353-358
56. Inoue N, Ramasamy S, Fukai T, Nerem RM, Harrisom DG (1996) Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells. Circ Res 79:32-37
57. Gracia CE, Kdcoyne CM, Cardillo C, Cannon RO 3rd, Quyyumi AA, Panza JA (1995) Effect of copper-zinc superoxide dismutase on endothelium-dependent vasodilation in patients with essential hypertension. Hypertension 26:863-868
58. Sato M, Yanagisawa H, Nojima Y, Tamura J, Wada O (2002) Zn deficiency aggravates hypertension in spontaneously hypertensive rats: possible role of Cu/Zn-superoxide dismutase. Clin Exp Hypertens 24:355-370
59. Cebeci SA, Kocaturk PA, Kavas GO (2002) Hypertension: does impaired endothelium-dependent relaxation affect superoxide scavenging? Biol Trace Elem Res 90:239-249
60. Sato M, Kurihara N, Moridaira K, Sakamoto H, Tamura J, Wada O, Yanagisawa H (2003) Dietary Zn deficiency does not influence systemic blood pressure and vascular nitric oxide signaling in normotensive rats. Biol Trace Elem Res 91:157-172
61. Yanagisawa H, Sato M, Nodera M, Wada O (2004) Excessive zinc intake elevates systemic blood pressure levels in normotensive rats-potential role of superoxide-induced oxidative stress. J Hypertens 22:543-550
62. Tsai HM (2003) Shear stress and von Willebrand factor in health and disease. Semin Thromb Hemost 29:479-488